Sentences with phrase «gene rearrangement analysis»

Not exact matches

Dorothy Romanus, lead author of the study, states «this analysis supports the value of multiplexed testing for EGFR and ALK gene rearrangements followed by molecularly - guided therapy in decisions surrounding coverage of related testing and targeted therapy.

This analysis discovered an average of 97 structural rearrangements of the genome per tumor, and some 9,653 mutations of various types in 5,712 genes.

The analysis also found that a significant fraction of tumors contained rearrangements and mutations of a gene called PREX2, and experiments confirmed that cancer - associated mutations of PREX2 promoted the growth of human melanoma cells in mice.

Details on the recurrently mutated genes, and structural and functional analysis of somatic rearrangements, are provided as supplementary materials.

MRD was assessed using polymerase chain reaction analysis of Ig / TCR gene rearrangements.