Sentences with phrase «gene regulation at»

The San Diego Epigenome Center, headed by Bing Ren, Ph.D., Professor of Cellular and Molecular Medicine at the University of California, San Diego School of Medicine and head of the Laboratory of Gene Regulation at the Ludwig Institute for Cancer Research, is an integral part of the five - year, $ 190 million push to accelerate research into modifications that alter genetic behavior across the human genome.

Professor of Quantitative Biology of Gene Regulation at the University Medical Center Utrecht and Utrecht University since 2013

He focused on gene regulation at the transcriptional level during his postdoc.

Professor of Quantitative Biology of Gene Regulations at the University Medical Center Utrecht and at Utrecht University

Not exact matches

Dean Hamer, the chief of gene structure and regulation at the National Cancer Institute's Laboratory of Biochemistry, wrote recently in Scientific American about his vision of a not - too - distant future in which an imaginary couple, Syd and Kayla, got to tweak the emotional makeup of their fetus.

Sankar Ghosh, professor of immunobiology at Yale University, explores the regulation of gene expression in developing and differentiating lymphocytes.

Today, a team of researchers from the University of Geneva (UNIGE), Switzerland, led by Emmanouil Dermitzakis, Louis - Jeantet Professor at the Faculty of Medicine, reveals that this is not always the case and that DNA methylation may play both a passive and active role in gene regulation.

The whole point of a gene drive is to disperse in the wild, but government regulations are designed to keep genetic engineering out of wild organisms, says Zach Adelman, a molecular biologist at Virginia Tech in Blacksburg.

Research coordinated by Osaka University has now shown that the nuclear protein complex cohesin must be expressed at sufficient levels in the early mouse brain to control gene regulation and allow development of healthy neuronal networks and behavioral characteristics.

The systems biologists proposed that — at least sometimes — circRNAs serve gene regulation.

Cavalli and his team at the Institute of Human Genetics (University of Montpellier / CNRS) are the first to show that regulation of gene position can lead to transgenerational inheritance.

Specifically, Toni Gabaldón's group at the Centre for Genomic Regulation in Barcelona has compared the Iberian lynx genome with those of other species, attempting to identify genes that have lost their function because they have remained isolated and the existence of a small population of specimens of this species.

«This step in the UK will stimulate debate on legal regulation of germline gene editing in clinical settings,» says Tetsuya Ishii, a bioethicist at Hokkaido University in Sapporo, Japan, who notes that some countries do not explicitly prohibit reproductive applications.

A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression.

At the nucleic acid level, understanding the precise regulation of genes through analysis of gene expression data will be of utmost importance.

«Along with previous examples of small RNA exchange between fungi and plants, our results imply that this cross-species gene regulation may be more widespread in other plant - parasite interactions,» said Michael J. Axtell, professor of biology at Penn State and an author of the paper.

Should there be regulations that compel a physician or the parents to alert siblings and others who may be at high risk of harbouring the gene?

«This study sheds light on this paradox and uncovers a way by which the stress hormone could prevent diseases, at least psychologically, through regulation of the Ppm1f gene» he adds.

«We concluded that RAC1 regulates lung branching morphogenesis, in part through the so - called canonical Wnt signaling pathway, which leads to the regulation of the transcription of many genes,» said principal investigator Denise Al Alam, PhD, of the Department of Surgery and the Developmental Biology and Regenerative Medicine Program at The Saban Research Institute.

«We set out to find out about human genes that are implicated in the regulation of the gut microbiome, and we found some that are,» says senior author Ruth Ley, an Associate Professor in the Department of Microbiology at Cornell University and the study's senior author.

Currently, there is no cure to stop or reverse any form of muscle - wasting disorders — only medication and therapy that can slow the process,» said Vittorio Sartorelli, M.D., chief of the Laboratory of Muscle Stem Cells and Gene Regulation and deputy scientific director at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

«The disruption of the circadian clock machinery seems to affect not only the rhythm of appetite regulation, but also the expression of the genes and proteins at their absolute level,» says Turek, whose team reports its findings online today in Science.

Researchers from the Institute of Neurosciences at the Universitat Autònoma de Barcelona (INc - UAB) and the Vall d'Hebron Research Institute (VHIR) are the first to demonstrate that regulation of the brain's Klotho gene using gene therapy protects against age - related learning and memory problems in mice.

He's also eager to return full time to his HHMI - supported lab at the University of California, Berkeley, which has shifted its work on gene regulation from wet biochemistry to imaging single molecules in living cells.

To determine whether shifts in the balance of anterior and posterior field occurred during fin - to - limb evolution, Onimaru, postdoctoral researcher currently at Sharpe's lab (CRG), and his colleagues carefully compared the expression, function and regulation of genes involved in anterior - posterior patterning in pectoral fins of catsharks, with those of mice.

At present, the regulation of gene drive research does not fit within the purview of any of the U.S. agencies involved in the Coordinated Framework for the Regulation of Biotechnology, which includes the Food and Drug Administration, U.S. Department of Agriculture, and the U.S. Environmental Protectiregulation of gene drive research does not fit within the purview of any of the U.S. agencies involved in the Coordinated Framework for the Regulation of Biotechnology, which includes the Food and Drug Administration, U.S. Department of Agriculture, and the U.S. Environmental ProtectiRegulation of Biotechnology, which includes the Food and Drug Administration, U.S. Department of Agriculture, and the U.S. Environmental Protection Agency.

«This is the first piece of evidence that humans may have a faster rate» of change in the regulation of gene expression, notes Caro - Beth Stewart, a molecular evolutionist at the State University of New York, Albany.

Dean Hamer, head of gene structure and regulation at the National Cancer Institute, is endeavoring to link religion to a specific gene.

Targeted gene therapies, however, had to wait for (1) the identification of the genes to target, (2) the cloning and / or sequencing of the relevant genes and in some cases, the specific disease - causing variant, (3) a full understanding of the normal gene function and regulation, and (4) the development of efficient ways to deliver genes to the relevant tissues at therapeutic levels.

Asst Prof Li, from the Neural Stem Cells Laboratory at NNI, added, «This important study suggests a link between a key neurological disease gene and regulation of microRNAs in the brain.

Scientists at the Centre for Genomic Regulation (CRG) in Barcelona, Spain, have developed a new technique to crack the underlying DNA code for the «control dials» that determine levels of gene activity in bacteria.

Scientists have discovered many points of regulation in the process of using a specific DNA template to make a protein, known as gene expression, that allow the cell to control how much of a certain protein is made at a certain time.

Indeed, to get the full picture of gene regulation we need to look at the three - dimensional organisation of the chromatin that also coordinates gene activity.»

He received his doctoral degree in 1996 at the Ludwig Maximilians University in Munich for work on activity - dependent regulation of neurotrophin gene expression.

In 1984, he moved to the Institute for Molecular and Cellular Biology, at Osaka University (Osaka, Japan), where his research group continued to study the regulation of interferon genes and discovered the interferon - regulatory - factor family of transcription factors.

With only a single gene and a toolbox of forward and reverse genetic approaches at hand, C. elegans offers an opportunity to explore the exact role of perlipin - related factors in fat regulation throughout development of many different somatic and germline cells.

Benedikt received his doctoral degree in 1996 at the Ludwig Maximilians University, Munich for work on activity - dependent regulation of neurotrophin gene expression.

The researchers were also able to see that over-consumption of saturated fats seems to be able to «turn on» certain genes in fatty tissue that increase the storage of fat in the abdomen and at the same time hamper insulin regulation.

What is known from global studies is that exposure to biologically active compounds, even at ng / L concentrations, can impact endocrine systems in nature and manifest as negative impacts like altered gene regulation, the presence of mixed reproductive tissues (intersex) and skewed sex ratios.

«We looked at regulations of genes, rather than genes themselves, and whether the gene is expressed in certain tissues or how much the gene is expressed there.

Marek is performing postdoctoral research in the lab of Nick Ingolia at UC Berkeley studying the regulation of gene expression.

Finally, Yingjie Guan, assistant professor (research) of orthopaedics at Brown and Lifespan, at the COBRE for Skeletal Health and Repair, talked about her detailed work on how mechanical regulation of gene expression, for instance by the micro RNA miR - 365, affects cartilage and bone health.

He joined the Dimitris Thanos lab «at the perfect time,» when a growing appreciation of the importance of chromatin in gene regulation presented many opportunities for the ambitious and eager young scientist.

Stephane completed his PhD at Cold Spring Harbor Laboratory studying RNA interference mediated gene regulation in Robert Martienssen's Lab.

Throughout his postdoctoral years, at Memorial Sloane - Kettering Cancer Center, and into his tenure at the University of Michigan, Dr. Al - Hashimi remained steadfast in his determination to solve the problem of how to visualize atomic motion, «to obtain a deeper understanding of gene regulation and to build new technologies for drug discovery and biotechnology.»

This metaphor is also a way of looking at gene regulation.

Fortunately, Paul Flicek and his colleagues at EMBL - EBI are rising to the challenge by helping to curate, catalogue and give access to the masses of genetic data being generated globally — not just gene sequences, but outcomes of studies into everything from gene regulation to protein function.

We study learning and memory at the genetic level to understand the structure, regulation, evolution and biological function of genes that are required for normal learning and memory.

Our colleagues at Gladstone are using this knowledge to search for small molecules that can affect gene regulation and reverse some of the problems caused by the loss of these transcription factors.»

«In addition to lending support to the idea that changes in gene regulation are a key part of our evolutionary history, these new results help to define exactly which regulatory factors may be important, at least in certain tissues.