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Gene circuit design strategy to advance synthetic biology.»
Researchers have turned to quantitative modeling to address
this gene circuit design challenge.
Not exact matches
According to Lu, this work advances the quantitative understanding of
gene circuit behaviors, and facilitates the transformation of
gene network
design from trial - and - error construction to rational forward engineering.
To do this, Lu and a team including MIT postdocs Lior Nissim and Ming - Ru Wu, have built a
gene circuit encoded in DNA
designed to distinguish cancer cells from noncancer cells.
Although showing great promise in the laboratory, these technologies require control and safety measures that make sure the engineered microorganisms keep their functional
gene circuits intact over many cell divisions, and that they are contained to the specific environments they are
designed for.