Sentences with phrase «gene expression analysis suggests»

The gene expression analysis suggests that activation of cell - type specific cationic channels may underlie the toxicity of the drug.

Gene expression analysis suggests that club cells express high amounts of antiviral genes in response to infection.

Not exact matches

A new meta - analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder — all previously unlinked to Parkinson's.

To begin to explore the cellular mechanisms that might be responsible for this response, histological analysis revealed less severe disruption of spermatogenesis and gene expression studies suggested that an interplay of ATP - binding cassette (ABC) efflux transporters and solute carrier (SLC) influx transporters in the testicular cells might be involved.

Using gene expression profile (GEP) tests like Oncotype DX to inform treatment decision - making for breast cancer is likely to be less cost - effective in community oncology practice than previous estimates had suggested, according to an economic simulation analysis published in the Journal of Clinical Oncology.

Deeper analyses, revealed that the RNA expression pattern of a rare variant of the NCAN gene was highly correlated with that of the previously suggested susceptibility genes for developmental dyslexia.

Expression and functional analyses of the gene strongly suggest that PDE4D plays an important role in atherosclerosis, most likely by influencing the proliferation and migration of smooth muscle cells within arteries that is central to the biology of ischemic stroke.

These results suggest that the effect of PMI on measured gene expression is relatively modest and can be further minimized by using appropriate covariate correction in analyses.

Dr Gilchrist said: «This study suggests that we may improve significantly on the widely used analysis methods for determining gene expression levels from high throughput sequence data: absolute quantitation offers a much sounder basis for determining changes in gene expression level, a measure widely used to determine the consequence of genetic, chemical or physical disturbances in living systems.»