Sentences with phrase «gene expression profiling
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Also see Claudia Liebl et al, Gene expression profiling following maternal deprivation: involvement of the brain renin - angiotensin system, Frontiers in Molecular Neuroscience., May 2009, Volume 2, Article 1

Gene expression profiling in persons with multiple chemical sensitivity before and after a controlled n - butanol exposure session

Breast cancer; Hormone receptors, hormone responsiveness, gene expression profiling, mutant ER, metastasis, predictive markers

On the publication of the article «Gene Expression Profiling in the Hibernating Primate, Cheirogaleus Medius», with the participation of José Luis Villanueva - Cañas (Josefa Gonzalez's group):

The new Driver - Map ™ Human Genome - Wide Gene Expression Profiling kit, is a targeted RNA expression profiling assay.

The FunGenES consortium collected gene expression profiling data from mouse ES cells in a coordinated fashion by streamlining techniques and standardizing experimental protocols among partners.

Designed and supervised the global analysis of the FunGenES gene expression profiling data and wrote the manuscript draft: AKH.

In recent years, a number of genome - wide approaches have identified transcripts present in mouse and human ES cells or their differentiated derivatives using a variety of gene expression profiling methods [24], [27]--[32].

Although the database described here was based on the gene expression profiling results of the FunGenES consortium, it can be easily adapted to incorporate available or future genomics data obtained in ES cells.

We have developed a novel «integrated» approach for gene expression profiling analysis that combines both «unbiased» and «biased» profiling (22)[Fig. 5].

Mar. 12, 2015 — Louis Staudt, M.D., Ph.D., a pioneer in gene expression profiling at the National Cancer Institute (NCI), will deliver the next Flexner Discovery Lecture on Thursday, March 19.

Doing so opened up a vast bank of viable samples for gene expression profiling, from which Dr. Golub and colleagues made some interesting findings.

Using gene expression profiling, Lau and colleagues identified 4 - 5 distinct clusters.

Approximately 50 % of PTCL are unclassifiable and categorized as PTCL, not otherwise specified (PTCL - NOS).1 Using gene expression profiling, PTCL - NOS lymphocytes can be distinguished from normal T lymphocytes, with deregulation of genes involved in apoptosis, proliferation, cell adhesion, and transcription regulation.2 Two subgroups of PTCL - NOS have been identified, which are characterized by high expression of either GATA3 or TBX21 / T - bet transcription factors and downstream target genes.3 However, actionable biomarkers closely related to the pathogenic mechanism need to be further investigated and may become potential therapeutic targets of PTCL - NOS. 4, 5

«Simultaneous mutation detection, copy number measurement, and digital gene expression profiling of high - grade serous ovarian cancer FFPE samples using Hyb & SeqTM targeted sequencing technology»

Gene expression profiling of di - n - butyl phthalate in normal human mammary epithelial cells.

Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa.

A cell - surface antibody panel was created and used for protein profiling alongside gene expression profiling.

Using an array of techniques, including RNA sequencing and targeted gene expression profiling, the researchers searched for links between gene activity and protein production in these tumors and the clinical outcomes of patients.

BioSpyder Technologies, Inc. is a relatively small biotech company that features a potent assay for high - throughput gene expression profiling.

Gene expression profiling of pulmonary neuroendocrine neoplasms: A comprehensive overview.

We subjected 474 mutant alleles curated from 5,338 tumors to pooled in vivo tumor formation assays and gene expression profiling.

Farkas et al. [29] and Ivanov et al. [30] reported on gene expression profiling in purified populations of rat retinal ganglion cells.

Gene expression profiling of substantia nigra dopamine neurons: Further insights into Parkinson disease pathology.

High quality of DNA / RNA products is the foundation of successful cancer research such as analysis of genetic alterations, gene expression profiling and next generation sequencing.

We offer a wide range of services, including capillary sequencing and genotyping, Illumina microarray - based gene expression profiling and genotyping, and next - generation sequencing (NGS).

«Gene expression profiling allows us to identify drugs that are potentially useful when given in combination.

Kinetics study on markers of the immune system by gene expression profiling of an in vivo heated tumor.

Gene expression profiling tests such as Oncotype Dx can help differentiate women who might benefit from chemotherapy versus those that might not.

Oncologists welcome gene expression profiling tests as an added tool in deciding whether women with early - stage breast cancer should have chemotherapy, a new study has found.

Gene sequencing provides an organism's genome sequence, but gene expression profiling reveals where and when in the body certain genes are active.

«Barriers to obtaining gene expression profiling test heightened perceived value.»

Gene expression profiling tests, such as Oncotype Dx, analyze the patterns of 21 different genes within cancer cells to help predict how likely it is that a women's cancer will recur within 10 years after initial treatment and how beneficial chemotherapy will be to her.

Ontario was the first province in Canada to fund gene expression profiling tests.

Rao's team used various approaches, including assays of telomerase activity, measurement of cell growth, and gene expression profiling of TSY - 1 treated cells, to determine how it acts.

The team used gene expression profiling and found that canine B - cell lymphoma expression profiles were similar in many ways to human B - cell lymphoma, thus paving the way for future studies, including therapeutic clinical trials in dogs and humans.

Lead author Johan den Boon, associate scientist with the Morgridge Institute for Research at the University of Wisconsin - Madison, says the research team used gene expression profiling on 128 specimens from the Study to Understand Cervical Cancer Early Endpoints and Determinants, or SUCCEED.

Gene expression profiling was performed on blood samples taken from 70 RA patients: 50 of whom had shown a good response to the anti-TNF biologic treatment adalimumab, 20 of whom had shown no response to this drug.

Citation: Lemay DG, Ballard OA, Hughes MA, Morrow AL, Horseman ND, Nommsen - Rivers LA (2013) RNA Sequencing of the Human Milk Fat Layer Transcriptome Reveals Distinct Gene Expression Profiles at Three Stages of Lactation.

They discovered that in the young, more immune cells called monocytes were recruited to the lungs, and that the gene expression profiles of these cells had more inflammatory features, causing greater inflammation and more severe lung injury.

In a recent attempt, oncologist Todd Golub of the Dana - Farber Cancer Institute in Boston, Massachusetts, and his colleagues collected gene expression profiles, taken from public databases, from 76 tumors.

By combining salivary gene expression profiles, postconceptional age and sex, this predictive model not only assessed the probability of feeding success, but also, and most importantly, highlighted specific developmental pathways that were likely contributing to feeding immaturity.

«Signaling pathways and gene expression profiles are very different in cells that grow in 2D and 3D cultures,» says Oksana Sirenko, a research scientist at Molecular Devices in Sunnyvale, California.

From this data, a relative gene expression profile for each sample is made.

If the gene expression profile of a neuronal type is measured, then the model predicts where in the brain that type of neuron can be found.»

To find out more about the differences between naive and primed pluripotent cells, the UW researchers first compared their gene expression profiles.

Researchers from BUSM and the University of Cyprus compared the markers on the surface of the cancer cells to gene expression profile of breast tumors deposited by researchers in international public databases and found that a molecule named IL13RA2 (IL13R alpha2) was abundant in metastatic or late - stage BLBC.

In vitro experiments and high - throughput RNA sequencing revealed that CTCF deletion profoundly altered the B lymphocyte transcriptional program, shifting cells from a gene expression profile typical of the germinal center to one more similar to that seen in plasma cells.

«These findings raise the possibility that by determining the gene expression profile of a patient's tumor, physicians may be able to identify aggressive disease at the outset of diagnosis and start treatment earlier,» said Sungyong You, PhD, an instructor in the Cedars - Sinai Department of Surgery and the first author of the study.

Whole - blood RNA gene expression profiles were analyzed in RS - III (recruitment, 2006 - 2008 [n = 762]-RRB- and SHIP - TREND (recruitment, 2008 - 2012 [n = 991]-RRB-, and fecal H pylori antigen in SHIP - TREND (n = 961).