«A three - dimensional map of the genome:
Gene mapping technique promises to unlock the power of proximity to find genes implicated in diseases.»
Using
gene mapping techniques, the researchers zeroed in on a mutation in the gene for hypocretin receptor 2.
Not exact matches
To test that idea in the ragworm, Tomer used a
technique he had developed to examine the complex brains of small creatures with unprecedented clarity: He created a high - resolution
map of the worm's brain cells according to the
genes they express, not just their shape and location.
There he pioneered the development of a novel
gene identification
technique of
mapping by admixture linkage disequilibrium.
These high - resolution
maps and new
techniques for defining genetic markers should greatly accelerate the hunt for
genes linked to diseases.
The scientists sampled the genetic code of 400 trees from 31 locations across northern North America and combined the genetic variations with computer modeling
techniques to
map how important
genes differ within balsam poplar and to locate where trees may have the best chance of survival in a rapidly warming world.
Using a
technique called whole - genome random sequencing, a TIGR team
mapped the entire two - million -
gene sequence of Thermotoga maritima, a bacterium first plucked from hot geothermal springs in Vulcano, Italy.
Positional cloning is a genetic
mapping technique used to pinpoint the location of specific traits of interest, such as disease - causing
genes or mutations, within the genome.
A new
technique produces complex
maps of
gene interactions and how they change as cells mature.
Approach: Wu's group used Brainbow, a transgenic
technique originally devised to
map individual neurons in the brain, to label cells stochastically using
gene cassettes that code for four uniquely expressed fluorescent proteins.
Their study used a pioneering genetic
technique to analyse
maps of DNA regions linked to an inherited risk of breast cancer and identify the actual
genes involved in raising a woman's risk.
Our approaches include
gene discovery,
mapping of signaling networks in cell culture models and in vivo functional analyses done through
gene knock - out and knock - in
techniques in mice.
The GENSAT project aims to
map the expression of
genes in the central nervous system of the mouse, using in situ hybridization and transgenic mouse
techniques.
The GENSAT project
maps the expression of
genes in the central nervous system of the pre - and postnatal mouse, using both in situ hybridization (ISH) and transgenic mouse
techniques.