Sentences with phrase «gene on brain function»

Not exact matches

For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disbrain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disbrain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBrain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBrain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disease.

Potentially explaining why even healthy brains don't function well with age, Salk researchers have discovered that genes that are switched on early in brain development to sever connections between neurons as the brain fine - tunes, are again activated in aging neuronal support cells called astrocytes.

Another doubled - up region contains enhancers that turn on some genes in the cerebellum, a part of the brain that coordinates movement, speech and performs other important functions.

Named after the IBM Blue Gene supercomputer it relies on, the Blue Brain Project has started modelling — in every detail — the cellular infrastructure and electrophysiological interactions within the cerebral neocortex, which represents about 80 % of the brain and is believed to house cognitive functions such as language and conscious thoBrain Project has started modelling — in every detail — the cellular infrastructure and electrophysiological interactions within the cerebral neocortex, which represents about 80 % of the brain and is believed to house cognitive functions such as language and conscious thobrain and is believed to house cognitive functions such as language and conscious thought.

The study highlights the dynamism of gene effects on brain function throughout the various stages of life such as adolescence or adulthood.

«Everyone was focusing on genes expressed in the brain,» says Levitt, «but this gene is important for repair of the intestine and immune function.

Crucially, the team also showed that a serotonergic neuron's gene expression and function depend not only on its location in the adult brain stem, but also on its cellular ancestor in the developing brain.

Such dramatic effects on brain size and function are unlikely in human carriers of BRCA1 mutations, the authors of the study note, but they propose the findings could shed light on the gene's role in brain evolution.

The gene - by - hormone interaction's effect on circuit function was found only with one of two versions of the gene that codes for BDNF (brain - derived neurotrophic factor), a chemical messenger operating in the circuit.

Based on studies of other genes related to FOXP2, the authors suggest that the loss of functioning protein from one copy of this gene might disrupt the proper growth of key speech and language structures in the brain.

«It really highlights that just a small difference in the regulatory regions of human DNA — even ones that don't really make a gene, per se, but help to control genes — can have a big impact on how the brain is built, and ultimately how it functions,» she said.

Understanding the effects that variations of these genes have on brain - cell function could lead to explanations of how they contribute to the condition and how it might be better prevented or treated.

These types of mice have played important roles in helping us to learn about the function of the gene on the brain.

When these genes are turned on, inflammatory chemicals are created called cytokines, which are directly detrimental to brain function.

Leading expert Dr. Cate Shanahan, calls vegetable oils «liquid death» and warns that if consumed on a regular basis, they can cause cellulite, decrease endothelial functions in arteries, facilitate rapid aging, bring on gene mutation as well as brain problems.

Finally, animal research focusing on brain - structural aspects related to early care and the new, conceptually important direction of studying environmental programming of early development through epigenetic modification of gene functioning is examined in brief.

We recognize that we do not yet know whether differences in Pcdh gene expression play a role in the effects of maternal care on brain function in offspring.

Nevertheless, these observations are consistent with the notion that T cells will be informative not only on immune specific genes that are associated with the HPA axis but also on some genes that are also involved in brain function.