Sentences with phrase «gene study helps»
April 17, 2013 Gene study helps understand pulmonary fibrosis A new study looking at the genomes of more than 1,500 patients with idiopathic pulmonary fibrosis, a rare and devastating lung disease, found multiple genetic associations with the disease, including one gene variant that was linked to an increase in the risk of death.
http://www.uchospitals.edu/ Not exact matches
I'm helping a group study a cell line that has been engineered to remove a particular gene.
He added that the method used in this study, called «network biology» — where computer systems are used to identify gene networks that work together to underpin disease — may also help find treatments for other conditions.
Specifically, the study reveals a mechanism that helps explain how dividing cells pass patterns of epigenetic information called methyl tags to their daughter cells, a crucial part of regulating gene expression across cell generations.
«Filter» hones GWAS results to help researchers avoid dead ends: A new strategy gives scientists a biologically informed way to select genes to study.»
A previous study found that today's dogs have many copies of the AMY2B gene, which produces an enzyme that helps break down starch, while wolves have only two copies.
Studies involving mice also helped to answer a key question: What turns on the activity of the per and tim genes in the first place?
A strain of wild Hawaiian worms has helped unmask long - studied genes as just plain selfish.
«This structural «footprint» we found seems to help these viruses get efficiently into the brain, which informs the design of potentially safer brain - targeted gene therapies,» said study senior author Aravind Asokan, PhD, associate professor of genetics.
A recent study in Ireland, for example, has uncovered evidence that famine survivors preferentially pass on a gene that helps the body store fat.
Whether you are studying the expression of thousands of genes simultaneously using DNA microarrays, or the interaction of multiple molecules to understand intercellular signalling, the skills that will help you understand your findings are statistics, computational techniques, and modelling — so all you really need is a mathematician.
Because the segment of DNA that they studied isn't associated with a gene that conveys an obvious benefit to the deer, any mutations that arise over time neither help nor hurt the creature's survival.
For example, we're funding research into faulty genes which make some men more likely to develop prostate cancer and studying how these genes could help doctors to identify patients who are more at risk.
This study could help us understand how changing messenger molecule tails could control gene expression in the context of regeneration.
The developing brain undergoes rapid and tightly coordinated changes in a molecular process known to help regulate gene activity, a new study shows.
By studying infected cells grown in a laboratory, the team found that a large number of CMV's genes help it hide from the immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the virus.
«An even larger study would help start identifying specific genes with a higher level of confidence,» he said.
The CREBRF variant appears to be rare in other populations, but studying how the gene works may help researchers better understand obesity.
«Using yeast as a model organism, we studied the Tup1 protein, a negative regulator of gene expression,» says Biology Professor Emanuel Rosonina, adding, «This protein binds to some genes and blocks their expression, helping to ensure genes that shouldn't be turned on remain inactive.»
The Grants had shown that gene flow has occurred in the finches of Daphne Major during the past 40 years, but the new study found extensive evidence for gene flow throughout the roughly 1 million years that the birds have occupied the archipelago, which has helped the researchers update their understanding of how the lineages diverged over time.
Large scientific studies in people and animals may help us understand the role of particular genes and neurochemicals in this process — and whether this process differs in the various forms of autism.
Some of these newly - discovered genes may help us better understand how a taste cell detects a given taste quality,» said Monell Center molecular neurobiologist Peihua Jiang, PhD, the study's senior author.
«Because the C282Y gene helps to control the effects of lead in the body and the mutation was spread randomly in the children, the findings of our study are difficult to explain unless lead is, in fact, part of the cause of ADHD, not just an association,» explained Nigg.
Studies like these two will eventually help tailor diets to people based on their physiology and genes, says obesity researcher Randy Seeley of the University of Cincinnati, Ohio.
«We don't know if studying the fish will directly help us,» said Rohner, «but evolution has tried a lot of gene variants over millions of years and I think that's smarter than anything we can come up with, even with machine learning.
The experiments set off a debate about the safest way to do gene drive experiments in the lab and helped prompt the Defense Advanced Research Projects Agency and the Bill & Melinda Gates Foundation to support the academies's study.
New studies of genes and isotopes are helping reveal how major migrations shaped who we are today.
Future studies, she says, may be able to shed light on specific genes that affect academic achievement, which could help diagnose or treat learning disabilities.
Using advanced computer analysis techniques designed to study and process biological data, the researchers identified SND1 among a handful of other genes that miR - 184 helps regulate.
This essentially gives us «barcodes» of specific gene loci, which we can use to help untangle the complex genetics of complex diseases,» said Andrey Rzhetsky, PhD, professor of genetic medicine and human genetics at the University of Chicago, who led the study.
Further studies showed that very similar genes controlled the process in animal and human cells, and also helped piece together how the genes work together to keep the cell's recycling centers running.
A new study describes research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.
They have made possible wholesale scans that turn up new gene modifications and variations, and the same should prove true for the new human gene arrays, says Joseph Ecker, a plant scientist at the Salk Institute for Biological Studies in La Jolla, California, who has helped pioneer whole - genome chips for Arabidopsis.
A study done by researchers at Fox Chase Cancer Center shows that many relatives of patients who undergo testing for a gene linked to breast and ovarian cancers misinterpret the results, and less than half of those who could benefit from genetic testing say they plan to get tested themselves — despite the fact that knowing your genetic status may help catch the disease in its earliest stages.
Various bat species that emit high - frequency squeaks to detect prey and avoid obstacles share a high degree of variation in the FOXP2 gene, according to a new study, suggesting that genetic changes in the gene helped promote the evolution of this ability.
«Information from this study could help lay the groundwork for therapies that address developmental missteps tied to Hox genes and their regulators.»
The study suggests that methods based on variance may help get the most from existing and future global gene expression studies.
In the new study, Burrows and colleagues focused on the protein HIC1, or «Hypermethylated in cancer 1, «so named because it was first identified in cancer cells; however, it also helps regulate gene expression in normal cells.
The genes studied, called Microcephalin and ASPM, help determine brain size.
A 2008 study at Sweden's Lund University demonstrated that drinking coffee lowers the risk of breast cancer, at least for women who have a relatively common variant of the gene CYP1A2, which helps to metabolize both estrogen and coffee.
«While longitudinal studies are needed to confirm our results, this study suggests that boosting proline levels in patients with the Val / Val gene may help address negative symptoms, whereas increasing proline in patients with the Met / Met gene may have the opposite effect,» said Dr. Clelland.
The researchers said the work demonstrates that, in fact, multi-tissue, multi-individual data can be used to identify the mechanisms of gene regulation and help to study the genetic basis of complex diseases.
So geneticists have been focusing on the dog as a possible model for gene searches because this lack of sequence variation may help them circumvent a frequent problem with studies in humans.
The new study, published online Jan. 13 in Oncotarget, helps to explain why some women with healthy BRCA1 and BRCA2 genes develop cancer.
According to a new study, a primitive protozoan called Giardia lamblia has at least one intron, a piece of «junk DNA» that exists in the middle of genes but doesn't help code for a protein.
«This may be the primordial gene that regulates nutrient sensing and helps an animal overcome stressful conditions — and helps an animal live a long time through dietary - restriction conditions,» says the study's senior author, Andrew Dillin, an associate professor of molecular and cell biology at the Salk Institute in La Jolla, Calif..
«Surprisingly, when we looked for shared gene variants that might help explain part of the link between migraine and heart disease, we found no shared gene variations between migraine with aura and heart disease,» said study author Aarno Palotie, MD, of the Broad Institute of MIT and Harvard.
Another clue came from the work of Frederick Kaplan at the University of Pennsylvania, an orthopedic surgeon and FOP pioneer who has been studying the disease for years, and who helped lead the team that found the FOP gene.
«Study of gene mutations in aplastic anemia may help optimize treament.»
In a collaboration with colleagues from Aalborg University, Technical University of Denmark (DTU) researchers have studied genes from wastewater treatment plants that may help bacteria to develop antimicrobial resistance.