Sentences with phrase «general transcription factor»

Specifically, we have shown that the condensin subunit Cnd2 binds directly to the most important general transcription factor, the TATA box - binding protein TBP, and that TBP recruits condensin molecules onto RNA polymerase III - transcribed genes and highly active Pol II - transcribed genes (many ribosomal protein genes) through the Cnd2 - TBP interaction (Figure A).

In the next set of experiments, they engineered DNA bubbles into the DNA that varied between 3 and 12 base pairs and tested what size bubble would allow transcription to proceed in the absence of TFIIH, the basal or general transcription factor they implicated in forcing these DNA bubbles open.

In addition, the total amount of a protein can be regulated by alternative splicing, which is illustrated in the current work by using the general transcription factor TBP (TATA - box binding protein) as an example.

Research Interests: RNA synthesis; RNA polymerase; promoter; general transcription factors; gene expression; gene regulation; chromatin structure and gene regulation

In the case of STAT6, we speculate that p300 may function as a result of its HAT activity and / or by bridging active interaction between STAT6 and general transcription factors.

Not exact matches

Additional gene duplication and divergence in eumetazoans further increased transcription factor gene family number, which in general are 2 to 34 times larger in eumetazoans than in Amphimedon.