* The notion «low - resource environments» is used to specify an environment where: (a) resources assigned for genomics research are scarce, (b) access to genomics knowledge and information is low, (c) implementation of Genomics is limited, (d) genomics education is relatively poor, and (e) collaborative opportunities in
genomic research with other institutions are rare for geographical, societal, economic or political reasons.
A big part of what we do at Revive & Restore is bring together scientists conducting cutting - edge
genomics research with the conservationists who are working in the field so that these new technologies may become an instrumental part of the twenty - first century conservation tool kit.
Not exact matches
His
research has spanned hematopoiesis, gene therapy, stem cell biology,
genomics and cancer, consistently focusing on bringing the very latest
research advances to patients
with heretofore incurable diseases.
Dr. Eric Topol, a cardiologist and professor of
genomics at the Scripps
Research Institute in California, said there was great potential value in consumer
genomics tests, particularly
with services like those developed by Geisinger, Invitae and Sema4 that are backed by strong data.
This is a fellowship program designed for genetics professionals
with an advanced degree who are early in their careers and interested in the development and implementation of national
genomics literacy efforts, informal science education, science education policy, program development, or science education
research.
Future resources from the NCI Center for Cancer Genomics (CCG), which oversees TCGA and other activities, will support more translationally focused
research, including databases
with genomic information on clinical samples linked to outcomes of their patient donors.
The inflammation cluster
research groups led by Saleh Ibrahim of the University of Lübeck, and John Baines of the MPI and CAU, correlated the
genomic variations of hundreds of mice that partially develop skin inflammatory diseases
with skin microbiota.
This study opens new avenues of
research aiming at integrating
genomic and epigenomic data together
with environmental exposures in order to elucidate the physio - pathological mechanisms underlying asthma and to promote the development of new therapies.
Physicians at Mayo Clinic's Individualized Medicine Clinic and researchers at the Translational Genomics
Research Institute (TGen) have personalized drug treatments for patients
with cholangiocarcinoma using
genomic sequencing technologies.
Using
genomic analysis to study cancer in dogs can help develop new therapies for humans
with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics
Research Institute (TGen).
Even before his 2002 Peking University Ph.D. thesis won a national award from the Ministry of Education, he helped found BGI, a nonprofit
genomics services and
research organization
with more than 3,000 employees, where he is now executive director.
«This basic study will allow more defined
research into the
genomic variations associated
with colon cancer that are in the region where BMP is regulated.»
While interested in African lineages, and how they interact
with each other, Professor Hayes is especially keen for Africa to inform
genomic research and medicine worldwide.
«Right now, the
research group is analyzing the nuclear genome the results of which could provide us
with information about its relationship
with the Neanderthals and about the existence of
genomic variations associated
with the immune system that accounts for the evolutionary success of Homo sapiens over other human species
with whom it co-existed.
For many molecular biologists, the discovery of the CRISPR - Cas9 system marked a new milestone in
research: finally,
genomic DNA can be cut
with high efficiency and precision, enabling genes to be disabled, modified or re-introduced.
Science Careers spoke
with Isabelle Vernos, chairwoman of the ERC Scientific Council's Working Group on Gender Balance and
research professor at the Centre for
Genomic Regulation in Barcelona, Spain, about the funding agency's efforts to bolster the prospects of female applicants.
«Depending on the
research questions, it may also be important to define the appropriate strategy to use, either whole - genome sequencing or just targeting some
genomic regions
with a gene baiting approach,» says Besnard.
Initial results were announced from the Trial Assigning IndividuaLized Options for Treatment (Rx), or TAILORx, a multi-center prospectively conducted trial of more than 10,000 women
with early stage breast cancer sponsored by the National Cancer Institute (NCI), part of the National Institutes of Health, and led by the ECOG - ACRIN Cancer
Research Group (ECOG - ACRIN)
with support from
Genomic Health, Inc..
«Some groups started calling their
research genomics this and
genomics that, even though it had little to do
with it.»
The
genomics era has had a profound impact on life science
research, leading to significant developments such as the use of expression quantitative trait loci (eQTLs), which link polymorphisms in single genes to quantifiable changes in gene expression associated
with specific diseases.
It's undoubtedly attractive to picture an «e-science» future, where the impacts of scientific
research such as environmental climate change and
genomic bioresearch are shared globally
with spectrally efficient 100 Gbps transmissions systems.
The regulatory function of novel targets will be validated in collaboration
with Judy H. Cho, MD, Ward - Coleman Professor of Medicine and Genetics and
Genomic Sciences, and Assistant Chief of
Research in the Gastrointestinal Division, and Jean Federic Colombel, MD, Professor of Medicine and Director of the Leona M. and Harry B. Helmsley Charitable Trust Inflammatory Bowel Disease Center, at they Icahn School of Medicine at Mount Sinai.
With over two years of
research, the purpose is to understand at a
genomic level the differences between these fungi.
Plant breeding
research elsewhere in the world has benefited from advances in
genomics and molecular markers, but plant breeding scientists in China do not work closely
with researchers in those areas, says Carl Pray, an agriculture, food, and resource economics expert at Rutgers University in New Brunswick, New Jersey, who has worked in China.
With the new research, scientists can now work with more citrus genomic information, Gmitter s
With the new
research, scientists can now work
with more citrus genomic information, Gmitter s
with more citrus
genomic information, Gmitter said.
During the last several years,
research efforts
with human cell lines revealed that the
genomic loci encoding tRNAs give rise to shorter tRNA fragments («tRFs»).
All other authors are
with The Institute for
Genomic Research (TIGR), Rockville, MD 20850, USA.
Investigators
with The Cancer Genome Atlas (TCGA)
Research Network have identified novel
genomic and molecular characteristics of cervical cancer that will aid in the subclassification of the disease and may help target therapies that are most appropriate for each patient.
And while becoming leaders in bioinformatics allows universities to push academic
research forward, federal funding can also help forge relationships
with industry: «It is critical to have universities collaborate
with industry,» stresses Cyrus Harmon, president and CEO of Neomorphic, a West Coast - based company that designs tools to scrutinize
genomic information.
The hostilities involve institutions (M.I.T. and Harvard versus University of California), gender (Doudna, Charpentier, Zhang), geography (east versus west coast) and what you might call über - institutions (the Broad Institute, which has become an empire of
genomic research under Lander's direction, especially after his leading role in the Human Genome Project, versus the Howard Hughes Medical Institute, whose president, Robert Tjian, is based at Berkeley and has co-authored at least one CRISPR paper
with Doudna, also an HHMI investigator).
Other educational events include a 3 - day workshop on
genomics given by faculty members from the University of Michigan's Center for Statistical Consultation and
Research and weekly colloquia
with special events.
«This [work] opens the way for comparative
genomics and identification of [unique features] in this group of ecological and economically important species,» says Etienne Danchin, an evolutionary biologist at the National Institute of Agricultural
Research in Sophia - Antipolis, France, who was not involved with the r
Research in Sophia - Antipolis, France, who was not involved
with the
researchresearch.
Researchers from Guillermo Montoya's team at the Spanish National Cancer
Research Centre (CNIO), in collaboration
with Isabelle Vernos» Group from the Centre for
Genomic Regulation (CRG), have uncovered the molecular interaction between TACC3 and chTOG, key proteins in forming the internal cellular framework that enables and sustains cell division.
«Massive
research consortia, like the ENCODE Project, have provided the scientific community
with a trove of information about
genomic function over the last few years,» says Siepel.
Olaparib was licensed in December for women
with ovarian cancer and inherited BRCA mutations, but the new
research suggests it could also benefit men
with genomic faults within their tumours.
Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through
genomic profiling shows that tumors
with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body.
For each species (or group), the authors describe possible applications in lab
research; summarize husbandry, genetics, and
genomics; list other resources; and provide basic protocols for work
with the organism.
CAMBRIDGE, MASSACHUSETTS — An unusual new consortium of companies has inked a 5 - year, $ 40 million deal
with Eric Lander, a gene mapper at the Whitehead Institute for Biomedical
Research and the Massachusetts Institute of Technology (MIT), to develop new techniques in «functional
genomics.»
In addition to the national awards in France, the Fulbright program has grants to conduct scientific
research in three French regions: the Alsace Regional Award (one award), which seeks candidates
with backgrounds in medical imaging, computer - assisted surgery, and medical robotics; the Aquitaine Regional Awards, which award three grants in 2007 - 08 and emphasize functional
genomics, viticulture and wine - related disciplines, biochemistry, optics, lasers, and physics; and the Nord Pas - de-Calais Regional Council Awards (four grants in 2007 - 08), which seek researchers for multidisciplinary projects covering a wide range of life, physical, and social sciences.
MacConaill noted that the results of Profile
genomic testing are being used to further
research within the institutions and are being shared more widely with initiatives like Project GENIE of the American Association for Cancer Research (AACR), which will help advance the field of precision m
research within the institutions and are being shared more widely
with initiatives like Project GENIE of the American Association for Cancer
Research (AACR), which will help advance the field of precision m
Research (AACR), which will help advance the field of precision medicine.
Wang says the experimental structure of the new college, in contrast
with China's traditional universities, will foster innovation across the life sciences, and will feature cutting - edge
research in medicine, biology,
genomics, and bioinformatics.
The Genome Sequencing Centers will play a pivotal role in our systematic effort to assess the range of
genomic changes associated
with malignancy,» said Mark S. Guyer, Ph.D., director of NHGRI's Division of Extramural
Research.
«This
genomic information will provide the
research community
with a powerful tool for uncovering new therapeutic targets and developing better strategies for diagnosing, treating and preventing cancer.»
Working together
with colleagues in Spain, Japan and Australia, researchers led by Luis Serrano, ICREA
research professor and leader of the Design of Biological Systems laboratory at the Centre for
Genomic Regulation, focused their attention on the organisation of DNA within an organism
with an extremely small genome — the pneumonia pathogen Mycoplasma pneumoniae.
Filed Under: Cancer
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Platforms in
genomics, comparative genetics, proteomics, functional biology, bioimaging and functional
genomics are complemented
with research communities (programmes) in biology, medicine and environmental sciences.
Robert Wildin, M.D., a clinical geneticist
with nearly three decades of experience in private and hospital - based medical practice, joined the National Human Genome
Research Institute (NHGRI) on Nov. 10, 2014 as chief of the
Genomic Healthcare Branch (GHB).
- Commitment to bring together
genomics research institutions form developing countries
with those from developed countries.
Joseph Walder, M.D., Ph.D., President and Chief Executive Officer of IDT, said, «IDT is excited to be the first
genomics company to have reached this agreement
with Caribou, a recognized leader in the field of CRISPR - Cas9
research.
He recently moved back to academia as an associate professor in the departments of Neuroscience and Human Genetics &
Genomic Sciences at the Icahn School of Medicine at Mount Sinai in New York, where he continues his basic
research and translational efforts in AD using a state - of - the - art experimental and computational toolkit, in collaboration
with Drs. Alison Goate and Anne Schaefer within the Ronald M. Loeb Center for Alzheimer's Disease.