Sentences with phrase «gladstone scientists»

Gladstone scientists are combining expertise and cutting - edge stem cell technology to tackle Alzheimer's disease.

Thanks to recent technological developments, new insights into brain health, and some creative thinking, two Gladstone scientists are embarking on research to replace lost or malfunctioning brain cells with new ones created from stem cells.

SAN FRANCISCO, CA — In a pair of new studies, Gladstone scientists discovered a specific neural circuit that controls walking, and they found that input to this circuit is disrupted in Parkinson's disease.

It is an ethos that inspires Gladstone scientists to translate their scientific discoveries from the lab to the clinic as swiftly and safely as possible.

By studying both the embryonic formation and adult function of the heart, Gladstone scientists are making new inroads in their understanding of cardiac health and disease.

Other Gladstone scientists on the studies include Yu Huang, Ian Spencer, Yu Zhang, Baoming Nie, Min Xie, Haixia Wang, Tianhua Ma, Tao Xu, Guilai Shi, Saiyong Zhu, Kai Liu, and Ke Li.

By combining resources, these partnerships enable Gladstone scientists to conduct research that exceeds the capabilities of an individual lab.

The goal of this seminar series is to feature scientists who are pushing the boundaries in their respective fields with enabling and disruptive technologies and share new and exciting research with Gladstone scientists.

In a revolutionary set of studies, Gladstone scientists pioneered a way to reprogram skin cells into heart cells and brain cells using only a combination of chemicals and without adding any external genes to the cells.

Other Gladstone scientists on the study include Priti Anand, Sean Thomas, Hazel T. Salunga, and Yu Huang.

Gladstone scientists are engineering tissues from stem cells to create better models of human disease.

About the Research Project Other Gladstone scientists on the study include Mark Jeng, Gregory Camus, Andrea Gramatica, Roland Schwarzer, Jeffrey R. Johnson, Philip A. Hull, Mauricio Montano, Naoki Sakane, Sara Pagans, and Nevan J. Krogan.

Gladstone scientists study how human skin cells can be reprogrammed into induced pluripotent stem (iPS) cells, and they are working to refine the production of these cells.

After developing and optimizing assays in - house, Gladstone scientists can transfer these assays to the SMDC or other external facilities to perform high - throughput screening with large compound libraries to identify potential drugs that may lead to therapies.

Other Gladstone scientists on the study include Nicole Stone, Emily Berry, Ethan Radzinsky, Yu Huang, Karishma Pratt, Yen - Sin Ang, Pengzhi Yu, Haixia Wang, Shibling Tang, Sheng Ding, and Kathy Ivey.

In a major breakthrough, Gladstone scientists transformed skin cells into heart cells and brain cells using a combination of chemicals and without adding external genes to the cells.

With access to the latest equipment and technical expertise for studying iPS and embryonic stem cells, the Core keeps Gladstone scientists at the forefront of the field.

Gladstone scientists Sheng Ding (right) and Tao Xu (left) discovered how to reprogram cells in our immune system.

The SMDC has allowed Gladstone scientists to design molecules to modulate the functions of proteins or specific cellular phenotypes and, most significantly, screen for drugs that could be used as therapies for disease.

In a final step, the Gladstone scientists collaborated with researchers from the European Molecular Biology Laboratory (EMBL) to create a crystal structure, or 3D representation, of the transcription factors co-binding on the genome.

In the new study, published in the Journal of Clinical Investigation, the Gladstone scientists linked telomere length to risk for or resistance to these types of diseases.

Other Gladstone scientists on the study include Grietje Krabbe, Sakura Minami, Jon Etchegaray, Praveen Taneja, Biljana Djukic, Dimitrios Davalos, David Le, Iris Lo, Lihong Zhan, Meredith Reichert, Mario Merlini, Michael Ward, and Katerina Akassoglou.

Gladstone scientists are exploring cellular reprogramming — turning one type of adult cell into another — in the heart as a way to regenerate muscle cells in the hopes of treating, and ultimately curing, heart failure.

Gladstone scientists collaborate with teachers to facilitate career discussions and lab lessons for students in public high schools in San Francisco.

In the future, Gladstone scientists hope to use direct reprogramming not only to treat heart failure, but also for spinal cord injury and devastating illnesses such as Alzheimer's and Parkinson's disease.

Other Gladstone scientists on the study include Gilad Doitsh, Zhiyuan Yang, Stefanie Sowinski, and Debbie Ruelas.

Other Gladstone scientists on the study include Yu Huang, Sanjeev Ranade, and Lei Liu.

Other Gladstone scientists on the study were Nathaniel Huebsch, Ekaterina Frolov, Edward Shin, Annie Truong, Michael Olvera, Amanda Chan, Yuichiro Miyaoka, Kristin Holmes, C. Ian Spencer, Luke Judge, David Gordon, Nevan Krogan, and Po - Lin So.

Now the Gladstone scientists report that these «bystander» cells are actually the victims of a failed or abortive form of viral infection.

Other Gladstone scientists on the study were Bogac Kaynak, Sean Thomas, Md Abul Hassan Samee, Daniel Le, Alisha Holloway, and Katherine Pollard.

In their pursuit of cures for debilitating diseases, Gladstone scientists are approaching precision medicine from new angles, researching the microbiome and protein networks that are critical for human biology.

Gladstone scientists discover shared characteristic among neurodegenerative diseases that occur across the lifespan

Other Gladstone scientists on the study include Emily Jones, Yuan - Hung Lin, Seo Yeon Yoon, Leslie Tong, Philip Nova, and Jessie Carr.

Dr. Huang's findings build on the work of other Gladstone scientists, starting with Gladstone Investigator, Shinya Yamanaka, MD, PhD.

In neurons, though, such breaks can occur even under normal circumstances, for example, after increased brain activity, as shown by the team of Gladstone scientists in an earlier study.

Other Gladstone scientists will serve as scientific partners (Katherine Pollard, PhD, Todd McDevitt, PhD, Nevan Krogan, PhD) or founding employees of the company, including Kathy Ivey, PhD, former director of the Gladstone Stem Cell Core and the new director of research operations at Tenaya.

Gladstone scientists identify inflammatory pathways as a potential therapeutic target for frontotemporal dementia

Gladstone scientists Drs. Bruce Conklin and Yuichiro Miyaoka have developed a technique that can efficiently edit the human genetic code — one letter at a time.

For example, Gladstone scientists are researching how autophagy — a process by which cells eliminate abnormal proteins — can help to prevent the destruction of brain cells.

Gladstone scientists have discovered how to make the three types of heart cells — cardiomyocytes, endothelial cells, and smooth muscle cells — out of a new type of cardiac stem cell created in a lab.

Gladstone scientists discovered a way to enhance the efficiency of stem cell reprogramming with a gene mutation that causes «stone man syndrome.»

Other Gladstone scientists on the study include Ian Spencer, Luke Judge, Mohammad Mandegar, Tamer Mohammed, Alice Sheehan, Annie Truong, Mike Saxton, Jennie Yoo, Deepak Srivastava, and Po - Lin So.

Gladstone scientists use and improve on each new generation of technology, pushing the boundaries of scientific innovation to study disease.

Supported by state - of - the - art core facilities and professionally trained staff, Gladstone scientists rely on the latest technologies to advance their work.

Gladstone scientists have identified the chain of events that causes healthy heart valves to harden like bone — and a potential way to correct this process by activating just a handful of genes.

Gladstone scientists are working to enhance CRISPR and develop the next version of the technology.

Other Gladstone scientists are investigating the network of brain cells that controls movements to figure out how its dysfunction leads to the symptoms of Parkinson's disease.

This investment is helping Gladstone scientists more quickly develop therapies for those suffering from Alzheimer's, or who are at increased risk of getting the disease.

Other Gladstone scientists on the study include Nik Mendoza - Camacho, Tracy Hookway, Casey Gifford, and Praveen Taneja.

Gladstone scientists are the first to produce a type of stem cell — derived neuron that could potentially help restore movement