Sentences with phrase «glial cells in»

Information from the journal Neurochemistry International shows that the nutrient is able to protect delicate glial cells in the brain against free radical damage that occurs as a result of low grade bacterial infection common in overweight and obese individuals.

In fact, cholesterol is so important that it is manufactured by the glial cells in the supportive tissues of the brain.

✓ Increasing the glial cells in your brain, which are responsible for creative thinking and long - term planning.

They found that the exposed rats were more likely to develop cancers, specifically malignant gliomas — a tumor of glial cells in the brain — and tumors in the heart.

Understanding the role of glial cells in glaucoma as well as what happens to the optic nerve where the retinal nerve axons leave the eye may present new therapeutic targets and even potential biomarkers of glaucoma.

There was also a Special Interest Group on «The Role of Astrocytes and Other Glial Cells in Retinal Function and Glaucoma.»

The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting.

By determining how changes in gene expression affect the fate of glial cells in mice, we hope to understand the key factors that govern neural cell regeneration in the human brain.

There are many more glial cells in the brain than neurons, and astrocytes are the most abundant of the glia, so if you take a sample of brain tissue, you're fairly sure to get some astrocytes as part of the bargain.

Cao (PI for Sub-project 1): Interaction between calcitonin gene - related peptide and CD40 on CNS glial cells in neuropathic pain.

But while substantial data (including AFFiRiS» [15] and Prothena's [20,22] preclinical work) give good reason to think that early clearance of AS neuropathology will decelerate the rate of SN DA neuronal loss, astrocytosis, and possibly accumulation of senescent glial cells in PD, there is no reason to think that doing so will prevent these phenomena entirely, if for no other reason than because many other factors also contribute to their occurrence.

Pathway analyses implicate glial cells in schizophrenia.

The cover image was created using images of neural rosettes derived from human iPSCs with and without a 15q11.2 microdeletion (round circles) and images of radial glial cells in the developing mouse cortex (thin filaments), and it is inspired by July 4th fireworks.

In a second test, Chen and his team used a transgenic - mouse model for Alzheimer's disease, and demonstrated that reactive glial cells in the mouse's diseased brain also can be converted into functional neurons.

«There are more reactive glial cells and fewer functional neurons in the injury site,» Chen said, «so we hypothesized that we might be able to convert glial cells in the scar into functional neurons at the site of injury in the brain.

Monje first became interested in neurons» role supporting tumors while working on childhood glioma, a cancer that strikes in the precursors to glial cells in the developing brain.

«Our finding runs counter to the belief that increasing the reactivity of astrocytes and other glial cells in the brain helps maintain tissue integrity following TBI.

This demonstrates a potentially crucial role for brain glial cells in mediating a fundamental physiological reflex.

Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma multiforme, a tumor of the glial cells in the brain.

There is more and more evidence to point to the importance of glial cells in modulating neuronal function and in mediating brain disorders,» says Guoping Feng, the James W. and Patricia Poitras Professor of Neuroscience.

Until recently it has been difficult to study the role of glial cells in controlling appetite or any other brain function, because scientists haven't developed many techniques for silencing or stimulating these cells, as they have for neurons.

The study is also the latest in recent years to implicate glial cells in important brain functions.

Small amounts of glycogen are found in the kidneys, and even smaller amounts in certain glial cells in the brain and white blood cells.

Glial cells in the spine may activate when pain - related neurons are firing, dosing both limbs with inflammatory substances that may trigger an excitatory response but that may also be toxic to nerves.

The stem cell closely resembles the radial glial cell in structure and behavior and, like the radial glia, has radial fibers which newborn neurons migrate along up to the neocortex.

Not exact matches

His lab differentiates iPSCs from autistic patients into neurons and glial cells, which they suspect may be releasing cytokines at levels higher than normal in autistic patients.

Supporting this idea, she found that mirror pain in rats vanished when glial cells were inactivated.

«I was very curious at that point what glial cells would be doing in the hypothalamus, since glial cells have been shown in other brain areas to have an influence on regulation of neuronal function,» she says.

MIT neuroscientists have discovered that brain cells called glial cells play a critical role in controlling appetite and feeding behavior.

In this study, the research team used a new technique developed at the University of North Carolina to study a type of glial cell known as an astrocyte.

In 2001, researchers at the Chinese Academy of Sciences in Shanghai reported that chronic morphine administration in rats activated glial cells called astrocytes in the spinal corIn 2001, researchers at the Chinese Academy of Sciences in Shanghai reported that chronic morphine administration in rats activated glial cells called astrocytes in the spinal corin Shanghai reported that chronic morphine administration in rats activated glial cells called astrocytes in the spinal corin rats activated glial cells called astrocytes in the spinal corin the spinal cord.

Scientists have found evidence that glial cells, which support and protect neural cells, may play a key role in the regenerative process.

Of these, connective tissue growth factor a (ctgfa) was expressed in glial cells during a key period of healing, as the cells were actively building bridges across damaged tissue.

Together, studies in zebrafish and mammalian models could inform new ways to manipulate glial cells after human spinal cord injury.»

Co-author Ken Poss of Duke University said that, in mammals, glial cells have traditionally been thought of as the scar - causing cells that present a roadblock for spinal cord repair.

Zebrafish in which ctgfa was disabled had glial cells that often failed to extend into the lesions, and the fish were unable to recover from spinal injury.

A key factor in the process may be enteric glial cells (EGCs), a class of cells that exist in the gut.

The virus appears to invade the brain by infecting a type of glial cell called olfactory ensheathing cells (OECs), which nourish smell - sensing neurons and guide them from the olfactory bulb to their targets in the nervous system.

«This particular circle can be found in excitatory neurons but not in glial cells,» says Monika Piwecka, one of the first authors of the paper and coordinator of most of the experiments.

Astrocytes — named for their starlike rays, which reach out in all directions — are the most abundant of all glial cells and therefore the most abundant of all the cells in the brain.

It may be that what we call our self, or the «I» in our perception of self, is made not of patterns of electrochemical synaptic logic (neurons chattering) but rather the aggregate experience of the mass of glial cells, each one contributing its particle of consciousness to the whole.

Future studies will look at the role p75 plays in two other types of cells — glial cells and skin cells.

They also applied it to human brain tissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtypes.

According to tradition in neuroscience, brain cells fall into two broad groups — neurons and glial cells.

This close - up of the cells involved reveals supporting glial cells (shown in red) are first to cross the gap between the severed ends.

Targeting HO - 1 is therefore another potential approach to improving photodynamic detection in human glial cell cancers.

Researchers were able to quantify the protective effect of dexamethasone treatment in protecting both satellite glial cell and neuronal apoptosis; in contrast, meloxicam treatment was only effective in protecting against satellite glial cell apoptosis and only after prolonged administration.

«We were surprised that it was expressed in only a fraction of glial cells after the injury.

We thought that these glial cells and this gene must be important,» said lead author Mayssa Mokalled, a postdoctoral fellow in Poss's group.

Some glial cells congregate near lesions, for instance, and in areas of the brain where learning is going on.