Unfortunately, in the absence of clear signs of
glucose dysregulation (hypo - or hyperglycemia, obesity, etc.), people have no reason to suspect something metabolically insidious is occurring.
Not exact matches
It refers to «sub-optimal
glucose metabolism», «low milk supply due to insulin
dysregulation», «mammary gland becomes highly sensitive to insulin during lactation», but never refers to low insulin levels.
The international research team behind the study now suggests that targeting inflammation and fibrosis in the small blood vessels of the pancreatic islets may offer a new way of treatment for age - dependent
dysregulation of blood
glucose levels.
Additionally, circadian misalignment is associated with alterations in cortisol and leptin secretion in relation to wake - sleep and feeding - fasting cycles causing further aggravating
dysregulation of
glucose and energy homeostasis (258, 259).
Blood sugar
dysregulation drives accelerated aging This kit helps support
glucose control and restore insulin sensitivity.
These include insoluble extracellular plaques made of beta - amyloid peptide (Aβ); intracellular neurofibrillary tangles (NFTs) resulting from the hyperphosphorylation of tau (a microtubule - associated protein); loss of hippocampal neurons; a decrease in production of brain acetylcholine; and a marked decline in
glucose usage in regions of the brain associated with memory and learning.5,11,20 - 22 All of these changes can be logically explained as the sequelae resulting from long - term
dysregulation of insulin signaling and
glucose metabolism.
So the two might go hand - in - hand, but in my opinion, it seems to be
glucose & insulin
dysregulation that's causing AD, rather than the other way around.
As mentioned, the regular consumption of a high - fat diet causes alterations in the characteristics of the intestinal microbiota, yet when antimicrobials are administered along with the Western - style diet, the detrimental diet - induced effects on systemic inflammation, systemic LPS burden and
glucose - insulin
dysregulation are minimized [21].
And in an ad lib setting, «Laboratory studies in healthy young volunteers have shown that experimental sleep restriction is associated with a
dysregulation of the neuroendocrine control of appetite consistent with increased hunger and with alterations in parameters of
glucose tolerance suggestive of an increased risk of diabetes» (Van Cauter et al., 2007).
The index represents the sum of physiological
dysregulations in the body of an individual in response to chronic stressful situation prior to onset of medical illnesses, and is measured by a combination of biomarkers of health such as adiposity, blood pressure and plasma
glucose level.