Along with intestinal stem
cells, the team identified differentiated nutrient - digesting and absorbing enterocytes, mucus - producing
Goblet cells, hormone -
secreting enteroendocrine
cells, and microbiome - regulating and sensing Paneth
cells, and they performed a series of assays that confirmed their functions.
These range from those that are very similar to the acid -
secreting glands of the stomach to those that look like intestinal crypts — indeed intestinalisation (defined by the presence of mucin
secreting goblet cells), is diagnostic for Barrett's in some countries.