Sentences with phrase «granulomatous disease»

NADPH oxidase, an important superoxide generating enzyme in inflammation, is implicated in seemingly every chronic disease, but those born with defective versions, or chronic granulomatous disease, suffer recurrent infections, and once all died in childhood.

IFN - γ (gamma) has been approved for use in a rare congenital disorder, chronic granulomatous disease.

Clinical research activities are focused on the implementation of experimental protocols based on gene or cell therapy for the treatment of genetic blood disorders such as ADA - SCID, Wiskott - Aldrich Syndrome, Metachromatic Leukodystrophy, Beta - thalassemia, Chronic granulomatous disease, Mucopolysaccharidosis Type I (Hurler).

Host - pathogen interface and inflammatory complications in chronic granulomatous disease, gastrointestinal complications in primary immunodeficiencies

Lentiviral - based gene therapy methods to modify human CD34 + hematopoietic stem cells have been investigated as a way of treating various hematological disorders including X-linked chronic granulomatous disease (X-CGD).

Targeted Gene Addition to a Safe Harbor locus in human CD34 + Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease.

Draft genome sequence determination for cystic fibrosis and chronic granulomatous disease Burkholderia multivorans isolates.

Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN - γ in a nitric oxide - dependent manner.

Colleen Dansereau, RN, MSN, CPN Program Manager, Gene Therapy Program As manager of the Gene Therapy Program, Colleen administratively manages the CAR T - cell therapy program as well as all administrative responsibility for all of the gene therapy clinical trials that take place at Dana - Farber / Boston Children's, for conditions including sickle cell disease, Wiskott - Aldrich Syndrome (WAS), and chronic granulomatous disease (CGD).

Patients with chronic granulomatous disease (CGD) are for example incapable of expressing the functional NOX2 enzyme.

Notably, research groups might be able to apply the approach described in this study to develop treatments for other blood diseases such as β - thalassemia, severe combined immunodeficiency (SCID), chronic granulomatous disease, rare disorders like Wiskott - Aldrich syndrome and Fanconi anemia, and even HIV infection.

Not exact matches

«Patients who develop granulomatous lymphocytic interstitial lung disease (GLILD) as a complication of common variable immunodeficiency (CVID) often have poorer outcomes.

One complication of CVID is called granulomatous lymphocytic interstitial lung disease (GLILD).

She successfully minimizes the use of drugs in a variety of rheumatological diseases: lupus, rheumatoid arthritis, the various spondyloarthropathies, giant cell arteritis, and granulomatous with polyangiitis (previously known as Wegener's vasculitis).

Granulomatous sebaceous adenitis: a disease of sebaceous (sweat) skin glands characterized by reactive tissue growth and autoimmune destruction of the sebaceous glands.

After coming to SNORT, Angie was diagnosed with a brain disease known as GME (Granulomatous meningoencephalitis), which is an inflammatory autoimmune disease of the central nervous system.

The researchers, led by Dr Steven Holloway from the University of Melbourne Faculty of Veterinary Science, have taken DNA from 100 dogs in the quest to determine what in their genetic makeup causes diseases such as diabetes, granulomatous meningitis (similar to multiple sclerosis) and immune - mediated haemolytic anemia, a condition which causes the immune system to attack red blood cells.

It can be quite confusing to owners and veterinarians alike because IBD is also called, Chronic Colitis, Colitis, Irritable Bowel Syndrome, Lymphocytic - plasmacytic Inflammatory Bowel Disease, Regional Enteritis, Granulomatous Enteritis or Spastic Bowel Syndrome depending on what symptoms predominate.

There are several disorders and diseases that can cause granulomas, or that have granulomatous dermatitis as a symptom.

B. Acute or chronic inflammatory diseases that result in increased mucosal permeability to protein • Inflammatory bowel disease (eosinophilic or lymphoplasmacytic enteritis) • Granulomatous enteritis (histoplasmosis, Pythiosis) • Intestinal neoplasia, (lymphoma, carcinoma) • Immunoproliferative enteropathy of Basenjis • Parasitic enteritis in young animals • Villous atrophy, gluten enteropathy, certain viral and bacterial enteritides • Chronic obstruction or intussusception

The Less common forms of feline inflammatory bowel disease are, depending upon the predominant inflammatory cell present, eosinophilic, neutrophilic, and granulomatous.