Sentences with phrase «group on clinical trials»

Not exact matches

In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.

Based on Han's presentation to the Depression Club, the group decided to move forward with a clinical trial in patients.

All groups of both species showed improvement over the course of 10 to 12 trials, but the healthy participants consistently reached the target with a more economic route, the team reports on today in the Journal of Clinical Investigation.

In the debate among clinics and researchers on SSRIs, it has been argued that SSRIs may lack specific therapeutic properties and that their beneficial effects observed in clinical trials, could be explained by different expectancies in the drug and placebo groups.

In focus groups, he found that many patients still weren't entirely clear on the implications of certain financial arrangements after hours of discussion, and he worries that even simple statements might not be understood or taken into account properly when patients are deciding whether or not to participate in a clinical trial.

Today's catch phrase is «evidence - based medicine,» and that «evidence» typically takes the form of results from clinical trials, in which potential treatments are tested on large groups of people.

Among the new voluntary efforts by pharmaceutical companies to post clinical trial data, the Association of the British Pharmaceutical Industry, one of the trade groups behind last week's proposal, will recommend that its members post trial results on a World Health Organization (WHO) global trials database that WHO hopes to establish in July.

The authors, who are now planning to begin clinical trials based on this study, state that the three enzymes can be promising therapeutic targets for a diverse and broad group of DLBCL patients.

The researchers then tested their scoring method using data on 688 AML patients in three different clinical trials, In each of these groups, patients with low scores (methylation patterns similar to normal HSCs) had approximately twice the median survival time of patients with high scores.

Further clinical trials are on - going internationally, and we hope to include data from them in a future analysis to determine whether the promise of today's results is confirmed in an even larger and more diverse group of patients.»

The patients were enrolled in clinical trials sponsored by St. Jude or the Children's Oncology Group, an international clinical trials group focused exclusively on pediatric caGroup, an international clinical trials group focused exclusively on pediatric cagroup focused exclusively on pediatric cancer.

However, the authors stress that «further clinical investigations will be essential to establish the optimal dose, duration and safety, and whether vitamin D2 or D3 have different effects on mortality risk, since the available trials are based on elderly populations in general (an age group with high competing risk of death often due to multiple co-existing disease conditions) and they do not typically include cause - specific deaths as the primary outcomes.»

UNDER PRESSURE Hitting a systolic blood pressure target of 120 millimeters of mercury took, on average, three drugs for a group of participants undergoing intensive treatment (orange line) in an NIH - sponsored clinical trial.

For the study, Baron performed an analysis of data from a 2010 clinical trial (by the same group of Northwestern researchers on the current paper) that demonstrated the ability of aerobic exercise to improve sleep, mood and vitality over a 16 - week period in middle - age - to - older adults with insomnia.

I'm beginning to think there's need for some kind of citizen's watch group that channels public outrage when patients are lured into clinical trials for treating serious diseases based on models / methods that haven't been properly vetted.

«The Translational Medicine group focuses on how to bring promising scientific discoveries into clinical trials.»

The Patient Advisory Group of the International Coordinating Committee (ICC) for SMA Clinical Trials has published a family - friendly set of guidelines for care in spinal muscular atrophy (SMA)-- click here to download the guide — to complement the physician guidelines published in August (for more on the physicians» consensus statement, see The Journal of -LSB-...]

«With so few patients aged 75 or older enrolled in clinical trials, critical information on the safety and effectiveness of new therapies in this age group is greatly lacking,» she said.

Based on our findings, the occurrence of cancer is much higher in adults over 75 years of age compared with the proportion of patients in this age group who enroll in clinical trials,» said lead study author Bindu Kanapuru, MD, medical officer in the Division of Hematology Products, Office of Hematology and Oncology Products in the US Food and Drug Administration's (FDA) Center for Drug Evaluation and Research, who presented the results at the 59th American Society of Hematology (ASH) Annual Meeting and Exposition, held December 9 — 12 in Atlanta.

Maren Monsen, Director of the Stanford Program in Bioethics in Film, will present a screening of her documentary film «Rare», which focuses on a rare genetic disorder, and discussion of the importance of patient advocacy groups and clinical trials process in the United States.

The NCTN — which will focus on early and late stage clinical trials for adults with cancer — will consist of fewer but larger groups of investigators and will distribute resources in a more effective way.

Towards the clinical translation of intra-articular injection of MSCs, the group of Kang Sup Yoon at the Seoul National University College of Medicine, Seoul, Korea report on their a proof - of concept phase I / II clinical trial intra-articular injection of autologous adipose tissue derived mesenchymal stem cells (AD MSCs)[6].

The Patient Advisory Group of the International Coordinating Committee (ICC) for SMA Clinical Trials has published a family - friendly set of guidelines for care in spinal muscular atrophy (SMA)-- click here to download the guide — to complement the physician guidelines published in August (for more on the physicians» consensus statement, see The Journal of Child Neurology.)

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

The approval came on the heels of the first phase III clinical trial ever shown to improve overall survival in patients with the disease, with median overall survival of 10.1 months, versus 6.4 months in the control group.

«We have a larger number of patients in our group than on any single clinical trial, so we hope this will be an opportunity for researchers to learn about us and a way for us to learn more about our condition.

The Focus on Cancer blog discusses a variety of cancer - related topics, including treatment advances, research efforts and clinical trials, nutrition, support groups, survivorship and patient stories.

A randomized trial is a type of clinical trial in which patients are assigned to groups on a random basis where they receive either the new experimental treatment or the established standard of care (or a placebo).

Capitalizing on our experiences with high - profile clinical trials such as the MedSeq Project and BabySeq Project and our strong relationship with the Laboratory for Molecular Medicine, our group is using a combination of modeling and clinical studies to examine the costs and consequences of integrating genome and exome sequencing into a variety of clinical settings.

This analysis of the NIH - funded Trial to Assess Chelation Therapy (TACT) focuses on the comparison of 2 treatment groups chelation + MV versus placebo infusions + placebo MV, evaluating a treatment strategy reflecting clinical practice, and not previously presented in detail.

Recently, our study group performed two clinical trials to obtain more information on TRD.

Dr. Mike Richards, DVM, who answers questions on the website VetInfo.com, has this to say about glucosamine and chondroitin: «In the clinical trials for Rimadyl (Rx) the placebo group was estimated to have improved by 15 % of the veterinarians and 25 % of the clients.

Researchers are now looking into the drugs effects on a clinical trial group of 30 middle - aged dogs.

A lack of differences between the COPE and control group mothers with respect to state anxiety and negative mood state during hospitalization may be attributable to the fact that the length of hospital stay for this full - scale clinical trial was approximately one - half of that in our pilot study.6 There might not have been enough time to demonstrate the positive effects of the COPE program on maternal anxiety and mood state during the short course of hospitalization in this trial.

Summary: (To include comparison groups, outcomes, measures, notable limitations) This study focused on adolescents and their families who completed a course of Multidimensional Family Therapy (MDFT) as part of a controlled clinical trial.

Summary: (To include comparison groups, outcomes, measures, notable limitations) A one - year follow - up was conducted on patients who received amitriptyline hydrochloride and / or Interpersonal Psychotherapy (IPT), each alone and in combination, as part of a four - month clinical trial.