Sentences with phrase «gut microbiome composition»

We provide users with personalized nutrition and behavioral recommendations based on their personal health records and their specific gut microbiome composition.

Alterations in gut microbiome composition and barrier function are associated with reproductive and metabolic defects in women with polycystic ovarian syndrome (PCOS): A pilot study.

Second, it implies that dietary and / or host genetic differences in ancient populations may be reflected in differences in gut microbiome composition and it confirms that the two indigenous cultures were indeed distinct.

Gut Microbiome Composition Predicts Infection Risk during Chemotherapy in Children with Acute Lymphoblastic Leukemia — Hana Hakim — Clinical Infectious Diseases

An emerging body of literature in adults has begun to establish clear associations between gut microbiome composition and a wide range of health outcomes.1 - 6 In contrast, comparatively little is known about the gut microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequences.

Overall stool microbiome community composition was characterized using generalized UniFrac analysis.30 Controlling for the effects of feeding method, delivery mode was strongly associated with infant gut microbiome composition (P <.001; Q <.001)(Figure 1A).

Not exact matches

In a previous study of 24 healthy women, vaginal microbiome composition became less diverse between the second and third trimesters of pregnancy and just before delivery was enriched with Lactobacillus species, likely contributing to vertical transmission of these bacteria during vaginal birth.21 In a study of 10 newborns in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcus.

We observed significant independent associations between the composition of the infant gut microbiome and both delivery mode and feeding method.

Changes in the composition and activity of the gut microbiome in early life can influence the immune system and these changes might indirectly lead to changes in asthma later in life,» said Dr. Anke Maitland - van der Zee, senior author of the study.

«Several studies have detected differences in the composition of the gut microbiome between healthy people and those with obesity and type 2 diabetes, but the cause and effect remain unclear,» says Mark McCarthy, and continues:

If researchers can get a handle on the gut microbiome's role, Baranzini can imagine a day when probiotics can be used to shift the composition of microbes in the gut to reduce inflammation.

A new study from researchers at the University of Alabama at Birmingham shows that Parkinson's disease, and medications to treat Parkinson's, have distinct effects on the composition of the trillions of bacteria that make up the gut microbiome.

It's currently a challenge to do this kind of microbial redesign — antibiotics reduce microbial burden but fail to induce major changes in bacterial composition, and from fecal transplant studies in the gut we know that bacterial populations return to a baseline population even after a major shift — so more work is needed to attempt a durable change in the vaginal microbiome.

Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers» genetics, the composition of her breast milk and the development of her infant's gut microbiota.

Both studies demonstrate that the composition of the gut microbiome — the swarms of microorganisms naturally dwelling in the intestines — determines how effective these cancer immunotherapies are.

«If testosterone drives the microbial composition of the gut, a compelling next step would be to determine if treatment of PCOS with testosterone blockers or oral contraceptives results in the recovery of the gut microbiome,» said Thackray.

«Women with polycystic ovary syndrome have less bacterial diversity in gut: Study finds elevated testosterone levels in women linked to changes in microbiome composition.»

Researchers at Harvard Medical School and Columbia University in the United States have developed a way to study the functions of hard - to - grow bacteria that contribute to the composition of the gut microbiome.

«Our findings point to two potential impacts from additional research — analyzing the diversity and composition of the microbiome to predict response to immunotherapy and modulating the gut microbiome to enhance treatment,» said Wargo, senior researcher on the project and co-leader of the Melanoma Moon Shot ™, part of MD Anderson's Moon Shots Program ™ to reduce cancer deaths by accelerating development of therapies from scientific discoveries.

They found that, while the species of bacteria present in the gut microbiome vary greatly between individuals, the composition of the microbiome is generally stable within the individual over time.

«Our stomachs produce gastric acid to kill ingested microbes, and taking a medication to suppress gastric acid secretion can change the composition of the gut microbiome,» said senior author Bernd Schnabl, MD, associate professor of gastroenterology at UC San Diego School of Medicine.

In turn, stress and emotions can change the composition of the gut microbiome.

HEIDELBERG, 11 March 2015 — Researchers at Harvard Medical School and Columbia University in the United States have developed a way to study the functions of hard - to - grow bacteria that contribute to the composition of the gut microbiome.

This is evidence that a person's genes can influence the gut microbiome's composition and in turn can shape the individual's phenotype.

The study, published July 21, 2016, in Scientific Reports, also showed significant changes in the gut microbiome after antibiotic treatment, suggesting the composition and diversity of bacteria in the gut play an important role in regulating immune system activity that impacts progression of Alzheimer's disease.

Another study from Sweden even demonstrated that the specific microbiome composition occurring in Alzheimer's patients induces the development of disease - specific amyloid - beta plaques, thereby establishing a direct functional link between the gut microbiome and Alzheimer's disease — at least in mice.

While genetic and epigenetic factors play between the host organism and the microbiota — determining which microbes successfully colonize the gut and other organs — the ultimate dictating force of the composition of an organism's microbiome is diet and environment.

Human gut microbiome Gut microbiome composition in lean patients with NASH is associated with liver damage independent from caloric intake: a prospective pilot study — Sebastião Mauro Bezerra Duarte — Nutrition, Metabolism and Cardiovascular Diseagut microbiome Gut microbiome composition in lean patients with NASH is associated with liver damage independent from caloric intake: a prospective pilot study — Sebastião Mauro Bezerra Duarte — Nutrition, Metabolism and Cardiovascular DiseaGut microbiome composition in lean patients with NASH is associated with liver damage independent from caloric intake: a prospective pilot study — Sebastião Mauro Bezerra Duarte — Nutrition, Metabolism and Cardiovascular Diseases

The present study shows that ancient DNA is not entirely degraded in humid, tropical environments, and that dietary and / or host genetic differences in ancient populations may be reflected in the composition of their gut microbiome.

«One thing this suggests is that maybe the reason it's not more effective is that people need both cranberries and a higher urine pH, or they need cranberries and appropriate inhabitants of their intestine, or the right microbiome composition in their gut, for the cranberry part to work properly.»

So, I know you mentioned gut microbiome, but what about body composition muscle mass in response to uhm — postprandial glucose?

But after you've been on a clean Paleo eating template for several months, you may actually be able to tolerate foods that you couldn't tolerate before as your body composition improves, your gut microbiome improved.

Butyrate is an important short chain fatty acid, with role in immunity, gi health, and gut microbiome's composition.

Ultimately, we were able to affect body composition and development in young mice by changing their gut microbiome through this exposure.»

The delicate balance between the human microbiome and the development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.

Sure, artificial sweeteners like sucralose, saccharine, and aspartame save on calories, but a recent Israeli study shows they can skew the composition of gut bacteria, or our microbiome in a way that promotes obesity and diabetes.

A study that looked at the mechanism behind dietary fibers effect on the microbiome, they hypothesized that «dietary fiber resists digestion in the small intestine, and enters the colon where it is fermented to produce [short chain fatty acids] that may enhance the healthy composition of gut microbiota.»

Research on human and gut microbiome is continuing to evolve, but what we do know is that the composition of microbes in our gut may influence way more than just digestion.

The composition of the gut microbiome can even alter behavior in mice; treatment with particular probiotics can also improve anxiety behaviors (mostly in rodents, but there are limited findings in humans as well).

Our study suggests that B. fragilis is able to ameliorate leaky gut by directly targeting tight junction expression, cytokine production and / or microbiome composition.

And what we know is the composition of the gut microbiome has such a profound effect on the brain.

A number of studies have shown that variations in the human gut microbiome are associated with different diet compositions as well as a number of medical conditions.