Not exact matches
Giving PPAR - delta a boost with an existing
drug was protective in
HD cells and mice, but we'll likely need to
research and test it further before it can go to the
HD clinic.
This is a welcome surprise, because it suggests a well - understood brain process might be a useful
drug target for future
HD research.
CHDI is a private, not - for - profit
research organization, working with an international network of scientists to discover
drugs that slow the progression or delay the onset of
HD.
Enroll -
HD aims to understand the disease, improve clinical care and enable clinical
research (eg biomarkers and future
drug trials).
However, other types of imaging could be useful for
HD research, like one that measures PDE10, the target for Pfizer's
HD drug.
This study was supported by the National Institute on Child Health and Human Development through cooperative agreements (U10
HD 27904; U10
HD 21397; U10
HD 21385; U10
HD 27856; U10
HD 19897), NICHD contract
HD 23159, Intra-agency agreements with the National Institute on
Drug Abuse (NIDA), Administration for Youth and Families (ACYF) and the Center for Substance Abuse Treatment (CSAT), and a National
Research Service Award from the National Institute on
Drug Abuse (1 F32 DA05971 - 01).