Sentences with phrase «hd gene results»
The expanded CAG sequence in the HD gene results in a huntingtin protein with too many glutamines at the start of it.
https://en.hdbuzz.net/ Not exact matches
HD is caused by a mutation in the human HTT gene that results in an abnormal expansion and misfolding of the corresponding huntingtin protein.
HD genes with CAG lengths between 27 - 35, which do not result in HD symptoms, but are longer than normal.
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder resulting from an extended number of CAG repeats in the Huntingtin (Htt) gene, for which no disease - modifying therapy is currently available, and comprises several cognitive and affective symptoms, as well as uncontrolled movement (chorea).
Since there are so many genes involved in polygenic traits such as HD, some few dogs with what we call a normal genotype (very few defective genes as evidenced by progeny results, for example) can be «forced» into dysplastic phenotypes if they are overfed and mineral - supplemented during their fast growth period.
That might mean he has few or no genes for HD but the results may also indicate that the bitches you used didn't have them, or the dog / bitch combination didn't have the complete set of genes necessary to produce HD.
The results from the shuffled and the transformed data sets were interpreted as undermining the major gene theory for elbow dysplasia, although the mixed inheritance models provided a clearly better fit to the data than did the polygenic models for both HD and ED.