Sentences with phrase «hiv reactivation»

«The implications for using noise also extend far beyond HIV reactivation, since random cellular activity contributes to a wide range of processes, from antibiotic persistence to cancer metastasis», said Dr. Weinberger.

Not exact matches

(B, C) Flow cytometric analysis of HIV - 1 gene expression in (B) mock infected or (C) latently infected CD4 + T cells under non-polarizing conditions, either at the basal state or after reactivation with antibodies against CD3 and CD28.

Aza - CdR and HDAC inhibitors do not synergistically reactivate latent HIV - 1 Latent HIV - 1 reactivation in the indicated J - Lat cell lines treated with aza - CdR, VPA, aza - CdR plus VPA, SAHA, or aza - CdR plus SAHA.

Therapeutic vaccination targeting conserved regions of HIV - 1 combined with HIV latency reactivation strategies may facilitate clearance of the viral reservoir in early - treated individuals.

«While HIV - 1 latency is likely to be a multifactorial process, we have shown that inhibiting the methylation of the provirus contributes to an almost complete reactivation of latent HIV - 1,» said lead author Steven E. Kauder.

«Interfering with methylation greatly potentiates the reactivation of HIV,» Kauder said.

She is currently a Research Fellow who is studying the immunological and virological characterization of HIV -1-infected patients who are taking antiretroviral therapy and various viral reactivation agents in several ongoing clinical trials.

Established a Jurkat cell model of HIV latency (5A8 cells) that is inducible by T - cell receptor cross-linking and displays drug reactivation profiles resembling that from resting CD4 T cells from aviremic patients.

Many of us are already infected with this organism, and recent studies show that most people with HIV disease that develop Toxoplasmosis are actually developing a «reactivation» of something they already had, but that didn't make them sick until their immune system deteriorated.