Sentences with phrase «hiv vaccine development»

It remains unclear exactly what this new organization will do.2 Such lack of clarity did not stop Lee Jong - wook, the World Health Organization's director - general, from calling it «a new political and financial dimension» to HIV vaccine development.

Today the founder and leader of the world's largest HIV vaccine network, Corey will deliver a plenary talk on the state of HIV vaccine development at next month's AIDS 2016 conference, the biannual meeting of the International AIDS Society, in Durban, South Africa.

He has coordinated FP5 and 6 projects and has collaborated in several international consortia on HIV vaccine development.

Dr. Polonis has spent most of her 28 years of research experience associated with the Military HIV Research Program and focusing on HIV vaccine development.

«Durable end to AIDS will require HIV vaccine development.»

These results have important implications for HIV vaccine development and for understanding the earliest events in HIV transmission.

«Immune responses provide clues for HIV vaccine development.»

«This gp41 protein from the virus envelope is not an absolute novelty in the long history of anti HIV vaccine development,» says Alexandru Rafila, Chairman of the Romanian Society for Microbiology in Bucharest.

Dr. Michael's research interests include HIV molecular pathogenesis and host genetics, HIV clinical research, and HIV vaccine development.

Not exact matches

The company also has vaccines in clinical development for cholera (Vaxchora), anthrax, HIV and hepatitis A.

These findings could help guide development of a new vaccine for pregnant mothers with HIV - 1.

And a new analysis of the STEP trial, published last November in Proceedings of the National Academy of Sciences USA, provides a warning that the very vectors (adenoviruses, which are also employed in other vaccine development work) used to distribute the inactive HIV strains can actually make the immune system more vulnerable to infection by recruiting susceptible T cells to mucous membranes, where they are more likely to be infected during sexual activity.

Hope for a vaccine One possible implication of this line of research is the development of an HIV vaccine.

The development of a vaccine remains the best possibility for ending the HIV pandemic.

Contributing to work on smallpox, polio, and vaccine development, primates allow research on potential treatments for hepatitis C and B, Ebola and Marburg viruses, and HIV / AIDS.

Researchers from the University of Zurich and University Hospital Zurich now reveal which factors are responsible for the human body forming such broadly neutralizing HIV antibodies, thereby opening new avenues for the development of an HIV vaccine.

Using the findings from this study, the team has designed vaccine immunogens to selectively trigger the cooperating antibody - producing B cells to cooperate to make broadly neutralizing antibodies in a manner that mimics broadly neutralizing antibody development in natural HIV infection.

Wherever the answer lies, the insights could help in the development of vaccines against other diseases that, like HIV, don't easily succumb to immune attack and that kill millions of people.

Despite their popularity — several HIV vaccines are in development using human adenoviruses — the approach has a significant drawback.

The move has outraged the broader community because the U.S. Military HIV Research Program plays a unique role in AIDS vaccine development.

And a new analysis of the stopped STEP trial, published online Monday in Proceedings in the National Academy of Sciences, provides a warning that the very vectors (adenoviruses, which are also employed in other vaccine development) used to distribute the inactive HIV strains can actually prime the immune system to be infected by recruiting susceptible T cells to mucous membranes, where they are more likely to be infected during sexual activity.

But scientific and economic obstacles have stymied the development of effective vaccines against many of the developing world's most deadly diseases, such as malaria and HIV as well as pneumococcus, the leading vaccine - preventable killer of children under the age of five.

«The idea basically is that a vaccine should induce antibodies T cells immune response, that would neutralise HIV in all of its forms,» explains Ulrich Fruth, vaccine development and evaluation team leader at the World Health Organisation, in Geneva, Switzerland.

The research, published in the September issue of Immunity, is part of a broad reverse - engineering effort by scientists around the world to use antibodies isolated from HIV - infected people to guide the development of a successful vaccine.

«Scientists identify immunological profiles of people who make powerful HIV antibodies: Findings provide insight for vaccine development.»

Reported in the January 16, 2015 issue of the journal Science, the new findings provide a cautionary tale for the development of vaccines aimed at eliciting robust CD4 T cell immunity against chronic infections, including HIV.

«We have learned in that period of time how formidable an adversary HIV is,» says immunologist Wayne Koff, senior vice president for research and development at the International AIDS Vaccine Initiative (IAVI).

Notably, the discovery of naturally occurring broadly neutralizing antibodies against HIV and studies of their stimulation in infected individuals have opened new avenues in vaccine development.

Ultimately, we believe, the only guarantee of a sustained end of the AIDS pandemic lies in a combination of nonvaccine prevention methods and the development and deployment of a safe and sufficiently effective HIV vaccine.»

In the piece, the authors note that behavioral, cultural and legal factors have hindered HIV prevention and treatment efforts and explain why those factors necessitate the development of an HIV vaccine.

Several approaches towards the development of an HIV vaccine are currently being pursued, Dr. Fauci notes.

Despite remarkable gains in the treatment and prevention of HIV infection, development of an effective HIV vaccine likely will be necessary to achieve a durable end to the HIV / AIDS pandemic, according to a new commentary from Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

A major goal of HIV - 1 vaccine development is to identify immunogens capable of inducing protective titers of broadly neutralizing antibodies (bNAbs) against circulating, neutralization - resistant (tier 2) viruses.

This new interest led to a student rotation at the Biomedical Center, which is focused on the development of a vaccine against HIV.

Ahead of this year's World Immunization Week — celebrated in the last week of April — we're reviewing some of the most important vaccine breakthroughs in recent history, as well as a looking to the future of vaccine development for diseases like HIV / AIDS, Zika, and Herpes.

Batista was one of a number of scientists involved in the study from the Ragon Institute, established in the Boston area by experts from Massachusetts General Hospital, Harvard University and the Massachusetts Institute of Technology, with the goal of working toward development of an effective vaccine against HIV / AIDS.

The HIV Vaccine Trials Network (HVTN) is the largest worldwide clinical trials network dedicated to the development and testing of HIV / AIDS vaccines.

When Georgia Tomaras of Duke University Medical Center opened this year's HIV Vaccines Keystone symposium last night, she said this is the first ever HIV Vaccines meeting that is held jointly with a meeting on B cell development and function.

«Research focused on basic B cell biology is the foundation for the development of an HIV vaccine designed to drive the B cell arm of the immune response.»

CHAVI - ID are two consortiums established by NIAID to undertake the immunologic research required to tackle the major scientific obstacles in the development of an effective HIV vaccine.

This understanding of how HIV - 1's «invisibility cloak» works could lead to the development of effective vaccines against HIV - 1.

«Until recently, we did not have substantial knowledge of the complexity of human genetic factors that influence HIV infection immune responses in this geographic region, which has been a major obstacle for vaccine development.

Today, «humanized» mice are in wide use in scientific research, promising hope for the development of vaccines for HIV, multiple sclerosis, and other autoimmune disorders.

Similarly, it was recently reported that maternal levels of HIV - specific Abs do not prevent the development of HIV vaccine — elicited Abs in HIV - exposed infants (126).

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He and his colleagues have made significant discoveries about how immune memory cells are created and how long they survive; understanding these mechanisms is crucial to the development of vaccines for HIV and other infectious agents.

As the Global HIV Vaccine Product Manager for the US Army, Dr. Ake advances the development of HIV vaccine candidates in preclinical and early clinical sVaccine Product Manager for the US Army, Dr. Ake advances the development of HIV vaccine candidates in preclinical and early clinical svaccine candidates in preclinical and early clinical studies.

He has extensive experience with the development of experimental vaccines for both genital herpes and HIV, and his lab has pioneered novel tests for diagnosing and monitoring therapies for viral infections.

Before joining IDRI, Tracey worked as a Protocol Development Manager with the HIV Vaccine Trials Network at the Fred Hutchinson Cancer Research Center where she led multi-disciplinary teams in the design and implementation of clinical trials evaluating candidate HIV and tuberculosis vaccines.

This led to the establishment of international collaborations aimed at preclinical identification, development and selection of HIV vaccine candidates, such as NeutNet, a worldwide consortium dedicated to the standardisation of HIV neutralisation assays, and the Humoral Immunity Platform of EUROPRISE.