This could lead to new
HIV vaccine strategies that are able to stimulate the rare precursors of these protective antibodies,» says Professor Lynn Morris, from the National Health Laboratory Service in the Wits School of Pathology who leads the research team at the NICD.
«BnAbs are thought to be akin to signposts — that they point to a path that might be followed by a future
HIV vaccine strategy through induction of bnAbs capable of preventing HIV infection,» said David Margolis, M.D., article co-author and director of the UNC HIV Cure Center.
Not exact matches
The induction of these antibodies that can neutralize a variety of
HIV strains is a key
strategy for a global
vaccine, Haynes said.
Recent research has yielded new information about immune responses associated with — and potentially responsible for — protection from
HIV infection, providing leads for new
strategies to develop an
HIV vaccine.
Mothe and her colleagues tried that
strategy with an
HIV vaccine made by Tomáš Hanke of the University of Oxford in the United Kingdom.
«Bringing the global
HIV epidemic under control requires new tools, bold
strategies and collaboration among a number of stakeholders,» said Hanneke Schuitemaker, one of the study authors and vice president, Viral
Vaccines Discovery and Translational Medicine, Janssen.
Although an autologous tier 2 NAb response is not sufficient for
vaccine protection against
HIV - 1, it may be a necessary step in various
strategies intended to induce bNAbs.
We aim to develop a globally - effective
HIV vaccine which, in combination with other proven prevention
strategies, would enable us not only to protect our Warfighters from
HIV, but would be critical in the control of the global pandemic.
Dr. Schief's work focuses on computation - guided and structure - based design of immunogens and immunization regimens, with the goal of inducing broadly neutralizing antibodies against
HIV and other pathogens that have frustrated traditional
vaccine design
strategies.
Randomized, Double - Blind Evaluation of Late Boost
Strategies for
HIV - Uninfected
Vaccine Recipients in the RV144
HIV Vaccine Efficacy Trial.
Five years ago, he enrolled in a study at the UNC School of Medicine, which was part of Dr. David Margolis» «kick and kill»
strategy for eradicating
HIV by flushing it out of hiding with a drug called Vorinostat and killing it with either a
vaccine
In the new issue of IAVI Report we wrote about how researchers at the AIDS
Vaccine 2010 conference in Atlanta discussed the limited window of opportunity for conducting clinical trials to test partially effective HIV prevention strategies, including HIV vaccine candidates and oral or topical antiretroviral pre-exposure prophylaxis (PrEP), in combi
Vaccine 2010 conference in Atlanta discussed the limited window of opportunity for conducting clinical trials to test partially effective
HIV prevention
strategies, including
HIV vaccine candidates and oral or topical antiretroviral pre-exposure prophylaxis (PrEP), in combi
vaccine candidates and oral or topical antiretroviral pre-exposure prophylaxis (PrEP), in combination.
This next stage in
HIV vaccine research requires a strengthened global
strategy that
The knowledge of the pathogenic mechanisms of infection and disease guide the development of intervention and prevention
strategies and new
HIV vaccine candidates.
BPRC applies molecular, biochemical and immunological know - how to provide new
vaccine and therapeutic
strategies for malaria, tuberculosis,
HIV, hepatitis C and other infectious diseases.