Sentences with phrase «hla gene complex»
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The human leukocyte antigen (HLA) system is a gene family that encodes the human major histocompatibility complex (MHC).
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Due to extensive linkage disequilibrium and multiple polymorphic candidate genes in the HLA complex, identifying the alleles responsible for these associations has proven difficult.
In 2002, two groups identified a particular gene variant in the major histocompatibility complex (MHC), called HLA - B * 5701, as being the key factor in hypersensitivity to abacavir.
Within the essential immune loci of the major histocompatibility complex, we find HLA - B to be the most polymorphic gene on chromosome 6 and in the human genome.