Similarly, Francis et al54 have shown that environmental enrichment can reverse the effects of early stress on
HPA activation and behavioral response to stress.
Because both background environmental stressors as part of the daily routine in the animal facility and social stressors afforded by the rats» social environment may have provided necessary
HPA activation for maternal behavior to exert a modulatory influence, such a correlation is at best consistent with a possible role of maternal care, but it can not be taken as conclusive evidence for sufficiency.
Although stress is generally viewed as having a negative influence on cognitive function, several recent studies demonstrate that
HPA activation can facilitate learning under conditions of arousal (19).
Not exact matches
For my masters project I studied the relationship between sociality and fitness in the rhesus macaque through non-invasive markers of immune
activation and
HPA axis function.
One mechanism is
activation of the hypothalamic — pituitary — adrenal axis (
HPA) axis, which is a complex set of interactions between three glands: the hypothalamus, pituitary gland, and adrenal glands.
The result of an imbalance in cortisol, otherwise termed Hypothalamic Pituitary Adrenal (
HPA) Axis dysregulation is weight gain, fatigue and brain fog, inflammation and immune system
activation, digestive issues, restlessness, impaired sleep, decreased cognitive function, and mental health conditions, such as anxiety and depression.
To the contrary, this seemingly contradictory set of findings that make up the current literature may be reconciled by considering the contribution of both a stress
activation of pups»
HPA axis and a maternal modulation of this stress response (39).
Maternal presence reduces
activation of the
HPA axis and ANS in young rodents exposed to a stressor (51), and in humans, the presence of a supportive caregiver is associated with reduced
HPA axis reactivity in young children (52).
Disruptive behaviour disorder has been linked to attenuated
activation of the main stress regulation systems: the Hypothalamic — pituitary — adrenal axis (
HPA - axis) and the autonomic nervous system (ANS)[4].
Animal studies have shown that maternal
HPA axis
activation not only affects the maternal immune system but also the offspring's immune system [20,25,26].
Thus, the physiological mechanisms underlying the associations found in the present study may be linked to maternal
HPA axis
activation.
Satisfaction with the partner, on the other hand, may reduce the stress - related
activation of the
HPA axis [29].
Youth with low
HPA reactivity along with increased ANS
activation characterized by both decreases in RSA and decreases in PEP had the most concurrent externalizing problems, consistent with broad theories of hypo - arousal.