Sentences with phrase «hts assay»

This particular type of cell - based HTS assay is used by many of the fast - track biotechs and pharmaceutical companies, and they take good care of their people.

HTS assays to screen for muscle - atrophy - preventing molecule are under development

Together these developments will allow pharmaceutical R&D companies to either incorporate these CETSA HT assays directly into their own HTS programs or to utilize Pelago's own HTS services.

«We could not have wished for a better collaborator to develop valuable CETSA HT assays, which have the capacity to transform targeted drug discovery»

Proteomes covers the multi-disciplinary topics of structural and functional biology, protein chemistry, cell biology, methodology used for protein analysis, including mass spectrometry, protein arrays, bioinformatics, HTS assays, etc..

Not exact matches

In this role, she focuses on the development of biologically relevant high throughput biochemical and phenotypic assays to enable high throughput screening (HTS) for a variety of drug targets for psychiatric disorders, and is currently interested in developing a high throughput calcium dynamics assay to monitor synaptic networks.

We had been looking for a senior scientist with experience in high throughput screening (HTS) assay development for a large drug discovery research program.

Phenotypic stability and unlimited self - renewal capacity of cell derived from pluripotent stem cells are essential properties for cell assay development for High Throughput Screening (HTS) strategies.

We will extend our HTS tests using different cell assays and extended chemical components libraries.

Shao L, Campbell U, Fang K, Powell AN, Campbell JE, Jones PG, Hanania T, Alexandrov V, Morganstern I, Sabath E, Zhong MH, Large HT, Spear KL In Vivo Phenotypic Drug Discovery: Applying a Behavioral Assay to the Discovery and Optimization of Novel Antipsychotic Agents.

Through the development of phenotypic assays and high throughput screening (HTS) thousands of compounds have been identified that inhibit the most serious malaria parasite, Plasmodium falciparum.

Then, the first objective of the HTS platform is to develop a robust cell based assay in microplates (96 - 384 - wells) with a specific read out.

Yulia has an extensive expertise in the assay development, assay miniaturization, high throughput screening (HTS), automation and data analysis.

An in situ activity assay with HT - 1080 gelatinases (Figure 8 B) shows that this is not a direct effect on the enzyme.

The gelatinolytic assays were carried out in two different ways to obtain complementary information: firstly, cells were treated or not with the test compound and samples from these were submitted to gelatinase zymography to detect the effects of the kahweol treatment on the expression of gelatinase activities; secondly, in some experiments, samples from control, untreated HT - 1080 fibrosarcoma cells were submitted to zymography and, after electrophoresis, different concentrations of kahweol were added to the substrate buffer to determine the potential direct effect of kahweol on gelatinase activity.

Conducted MTS and HTS functional screens (mGLUR2, mGLUR4, mGLUR5 and mGLUR7) and performed Dissociation and Association Kinetic Assay using FLIPR calcium mobility assay on cells transfected with metabotropic glutamate receAssay using FLIPR calcium mobility assay on cells transfected with metabotropic glutamate receassay on cells transfected with metabotropic glutamate receptor.

Tags for this Online Resume: High - Throughput (HTS) and High - Content Screening (HCS), Research Scientist, Laser Scanning Confocal Microscopy and Spectrophotometry Usage and Analysis, Murine manipulation, • ELISA • Western Blot, Flow Cytometry, Microbiology and Immunology, cell - based assays, molecular biology techniques