The researchers, led by Professor Sten Eirik W Jacobsen at the MRC Molecular
Haematology Unit and the Weatherall Institute for Molecular Medicine at the University of Oxford, investigated malignant cells in the bone marrow of patients with myelodysplastic syndrome (MDS) and followed them over time.
Co-authors of the study were Giovanni Cazzaniga, PhD, Maria Daniotti, BSc, Giuseppe Masera, MD, and Andrea Biondi, MD, of Centro Ricerca Tettamanti, Clinica Pediatrica, Universita di Milano, Ospedale San Gerardo, Milan, Italy; Osborn B. Eden, FRCP, of the Academic
Unit of Paediatric Oncology, Christie Hospital NHS Trust, Manchester, UK; G. M. Addison, FRCPath, of the Department of Clinical Biochemistry, Royal Manchester Children's Hospital, Manchester; and V. Saha, FRCPCH, of the Department of Paediatric
Haematology and Oncology, Royal London Hospital, London.