Sentences with phrase «haplotype mapping of»

Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies.

The Hap Map paper, appearing simultaneously online ahead of print in Science, is entitled, «A First - Generation Haplotype Map of Maize;» the corresponding author is Edward S. Buckler.

Not exact matches

All three teams found sections of DNA — haplotypes — that differed and ultimately pinpointed a single - letter difference that changed the amino - acid content of complement factor H. HapMap researchers say that refining the map further will speed up such discoveries, and they plan to release a new version this month that will include 4 million single - nucleotide variants.

After months of passing the hat among countries and private companies, the U.S. National Institutes of Health (NIH) announced today that it has garnered the $ 100 million the 3 - year effort to construct a so - called haplotype map is likely to cost.

Efforts include the National Institutes of Health Diabetes Genome Anatomy Project and another NIH - sponsored venture, the International HapMap Project, which is creating a map of regions in the human genome called haplotypes, where the underlying DNA influences common diseases like diabetes.

In response, Page and colleagues devised what is known as SHIMS (single - haplotype iterative mapping and sequencing) to establish a definitive reference DNA sequence of the Y chromosome.

To study natural selection, the team combed the International Haplotype Map for long stretches of DNA flanked by a single nucleotide polymorphism (SNP, or «snip»)-- that is, an altered base, or «letter,» in the genetic alphabet.

Their content is optimized for genetic mapping in the Collaborative Cross and Diveristy Outbred populations; for discriminating haplotypes from common laboratory strains and substrains; and for evaluating the ancestry of wild - caught mice.

The maize reference genome and the haplotype map are published online today ahead of print in the journal Science, in addition to a supplementary poster on the maize genome placing the plant and the sequencing project in historical and cultural perspective.

The HapMap, a shorthand for haplotype map, gauges diversity in the maize genome by comparing 27 distinct genetic lines of the plant with the reference version.

As a demonstration, we use the gPBWT to quickly count the number of haplotypes consistent with random walks in a genome graph, and with the paths taken by mapped reads; results suggest that haplotype consistency information can be practically incorporated into graph - based read mappers.

For efficient mapping of these mutants and mutation identification, we devised a new mapping strategy based on identification of mutant - specific haplotypes.