Sentences with phrase «heart cells experiment»

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Scientists have long experimented with organs - on - chips: tiny representations of human organs, such as lungs, hearts and intestines, made from cells embedded on plastic about the size of a computer memory stick.

«Before this study, it was not known if it is possible to produce sufficient numbers of these cells and successfully use them to remuscularize damaged hearts in a large animal whose heart size and physiology is similar to that of the human heart,» said Dr. Charles Murry, UW professor of pathology and bioengineering, who led the research team that conducted the experiment.

The results of the experiment appear in the April 30 advanced online edition of the journal Nature in a paper titled, «Human embryonic - stem cell derived cardiomyocytes regenerate non-human primate hearts.»

The team's further experiments on cultured heart cells confirmed that GDF - 11 stops the thickening growth seen with age.

The second key experiment showed the effect of transferring activated T - cells from heart - attack mice to healthy mice.

Two key experiments demonstrated this necessary and sufficient role for the activated T - cells, which presumably attack heart muscle tissue in an auto - immune fashion.

The day after his disciplinary dismissal from University of Tokyo for «damaging the university's honor or credibility,» Hisashi Moriguchi maintained in an interview with ScienceInsider that he really did participate in a groundbreaking experiment to treat a heart disease patient with cardiac muscle cells derived from the patient's own induced pluripotent stem (iPS) cells.

After the pig experiment worked well, he used his Boston area facility to culture the 30 million cardiac muscle cells that he says were injected into a heart disease patient in mid-2011.

The experiments reveal that the sudden loss of energy supply to the heart cells and the subsequent rapid «reboot» during treatment causes mitochondria to falter and trigger a whirlwind of aberrant electrical signals.

In their experiments, the researchers noted that the mitochondria of heart cells that lost oxygen and nutrient supply for a half - hour recovered smoothly.

But the scientists noticed something odd when they ran control experiments in which they injected the hydrogel without added cells: Some of the animals» hearts still showed improvement compared with untreated animals.

Experiments on mice and on heart cells obtained from infants born with congenital heart disease suggest that neuregulin 1, a human growth factor, can put infant heart cells on a path that mimics normal growth rather than stalling out.

In the case of the Circulation paper, which reported a surprisingly high turnover rate for muscle cells in the adult heart, Leri and Anversa say that Kajstura apparently altered, without their knowledge, data from mass spectrometry experiments performed at Lawrence Livermore National Laboratory (LLNL) in California.

Sean Wu, who studies heart stem cells at Stanford University in Palo Alto, California, says the NIH notice prompted Stanford to urge scientists to be sure their experiments didn't violate the new rules.

In previous experiments, neural stem cells have been able to integrate into developing embryos and turn into many different types of cells, including heart and liver (ScienceNOW, 1 June) and even blood (21 January 1999).

Then an experiment in 2005 found that young blood returned the liver and skeletal stem cells of old mice to a more youthful state, and work in 2012 discovered that young blood can reverse heart decline in old mice.

Stem cells in parts of the heart that have survived a heart attack can be prodded to regenerate tissue that was killed by the attack, recent experiments suggest.

In these experiments, exactly how the stem cells improved heart function remains controversial.

In a series of experiments, Haldar discovered that JQ1 stops the harmful gene expression that enlarges the heart and damages heart cells.

His studies, ranging from molecular experiments to clinical trials, have generated comprehensive evidence for the efficacy of omega - 3 in preventing cardiac sudden death and established the mechanism by which omega - 3 fatty acids can reduce cardiac arrhythmia by interacting with membrane ion channels and stabilizing the electrical activity of heart cells.

But initial experiments on human fibroblasts from three sources — fetal heart cells, embryonic stem cells and neonatal skin cells — revealed that the GMT combination alone was not sufficient.