Sentences with phrase «how tumor treatments»

Not exact matches

The method involves tagging a molecular drug delivery vehicle with synthetic DNA that can then be used to see how cancerous tumors are responding to specific treatments (the drugs themselves are placed into these tagged nanoparticles).

Appearing alongside the heads of five of NIH's 27 institutes and centers, Collins instead offered examples of how NIH research has led to new drugs for cystic fibrosis and cancer treatments that help the immune system fight tumors.

Although there have been great advances made in the treatment of leukemias and other cancers, little is known about how Glioblastomas are formed and how these tumors infiltrate the brain tissue.

If hypofractionated radiation with curative intent can reduce the treatment time for lung cancer patients by half with no greater toxicity, and with equivalent — if not better — tumor control and survival outcomes, this research could result in a change in the paradigm of how a large subset of locally advanced NSCLC patients are treated.»

Now that we know more about how cancer originates and how tumors re-grow after treatment, we can design new therapies to prevent this.

However, some human tumor cells may also be hard to infect with viral therapies, Dr. Cripe reasoned, and knowing how cells respond in those situations could also be important to improving cancer treatments.

Anil Potti had published papers in prominent journals identifying gene signatures in tumors that could predict how a patient would respond to treatment.

Detecting the presence of tumor estrogen or HER2 receptors with PET scans would enable oncologists to examine all sites of cancer for each patient, choose the appropriate drug treatment more quickly, monitor the tumor for changes that would necessitate a switch to another treatment, and even evaluate how well a drug is hitting its receptor targets.

A UNC Lineberger Comprehensive Cancer Center discovery of just how a certain tumor suppressor molecule works to prevent tumor growth could lead to a personalized treatment approach for colon cancer.

«By understanding how stress accelerates invasion in aggressive breast tumor cells, this work will inform future studies into whether beta - blockers could be a useful adjuvant therapy in the treatment of some aggressive breast cancers.»

«We had a hypothesis about how these treatments would work together, and when we did biopsies of patients» tumors we found that they were cooperating in just the way we thought they would,» says lead author Antoni Ribas, director of the Immunology Program at the UCLA Jonsson Comprehensive Cancer Center.

Writing in the Journal of Experimental Medicine last week, researchers revealed how some cancer treatments can trigger an inflammatory response that makes tumors stronger.

The study also suggests how ovarian cancer treatments can be tailored based on the metabolic profile of a particular tumor.

This finding may help researchers decipher how to inhibit the growth of tumors that have become resistant to other treatments.

In their report that has received advance online publication in Nature Nanotechnology, a research team based at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) describes how a nanomedicine that combines photodynamic therapy — the use of light to trigger a chemical reaction — with a molecular therapy drug targeted against common treatment resistance pathways reduced a thousand-fold the dosage of the molecular therapy drug required to suppress tumor progression and metastatic outgrowth in an animal model.

This was reflected in how much more efficient PMIL - delivered treatment was in the animal models compared to either treatment alone, since PDT simultaneously sensitized the tumor to the second therapy.

The new findings could help physicians prescribe the most effective treatments for each patient based on how genes are activated in the individual tumor.

Of particular interest are how tumor - specific metabolic changes promote oncogenic progression and how these changes can be exploited to develop more effective treatment options.

Answering important clinical questions — such as whether genetic diversity is a risk factor for aggressive tumor development or how it relates to treatment resistance — requires analyzing samples from many patients with different types of cancer.

The idea was immediately controversial but Hendrix and others have since pieced together a picture of how tumors build their own blood vessels and how they can affect prognosis and treatment.

Sequencing RNA, not just DNA, could help doctors predict how prostate cancer tumors will respond to treatment, according to research published in the open access journal Genome Biology.

Therefore, it is useful to identify tumor features that can serve as «predictive biomarkers» to forecast how a person's tumor might respond to a particular treatment.

«The surprise was how well this worked in clearing so much tumor so rapidly,» says immunologist Bruce Levine of the University of Pennsylvania, one of the scientists who created the new treatment.

With the new MIT sensor, doctors could track the state of the tumor and predict how it might respond to radiation treatment, according to the researchers.

That unpredictability includes how the tumor will react to treatment.

Using 80 of the successful tumor xenografts — from the Greek «xenos» meaning «foreign» — he compared how the mouse's tumor responded to a drug or drug combination with the treatment response of the corresponding human patient.

What followed is an illuminating tale of how one woman's intersection with experimental research helped open a new frontier in cancer treatment — with approval of a drug that, for the first time, capitalizes on a genetic feature in a tumor rather than on the disease's location in the body.

The technology successfully tracked in real - time how the diversity of tumor cell populations were changing in response to particular therapies for all of the patients studied, and was highly predictive of treatment effectiveness and patient outcomes.

Those early results are very positive, and strongly indicate that the nanoparticles could be useful for assessing how effective a therapy is on a much shorter time scale than current treatments, which usually rely on observing the size of the tumor.

To that end, Sharma gave an overview of MD Anderson's efforts to comprehensively characterize the activity of the immune cells in the patients they treat, and they've already analyzed over 42,000 tumor tissue samples, from both before and after treatment, looking for clues regarding how treatment outcomes relate to immune cell infiltration into tumors.

Their next steps are to characterize how these treatments affected NK cell function as well as determine the reactivity of patients» T cells against tumor mutations.

«The technology could also greatly improve our ability to study how tumor cells change in response to treatment and could help answer important biological questions about how treatment resistance arises.»

By uncovering new biological markers, the scientists hope to develop tests that individualize treatment by showing how the GPS system of a tumor operates.

These research collaborations have the power to answer questions critical to improving cancer outcomes, such as how tumors develop drug resistance, and what treatments are most effective against particular genomic traits.

For each treatment scenario, the model hosts millions of competitions to simulate how the tumor will most likely progress over time.

He's studying how tumor heterogeneity affects treatment and the role of microRNAs in pediatric cancers and leukemia.

Patients were often put through grueling — and expensive — treatment protocols without knowing how their tumors would react.

Other radiation treatments that require targeting the tumor from an external source, which exposes healthy tissues and limits how high a dose can be safely delivered.

Her goal is to define the molecular architecture and functional significance of a niche, determine how tumor growth impacts the niche, learn how benign and malignant cells compete within a niche, and use this knowledge to design precisely targeted anti-cancer treatments that spare normal bone marrow and improve the efficacy of stem cell - based therapies.

Areas of focus include: understanding how tumour - reactive T cells and B cells promote patient survival in cancer; defining the effects of standard treatments on tumor immunity; and using genomic approaches to identify novel tumour mutations that can serve as target antigens for immunotherapy.

How tumor cells gain resistance and / or avoid these therapies and which patients may benefit from these treatments is currently unknown.

how detoxing is gentle and simple and pushes out the treatment chemicals and tumor waste (the dead cancer cells that remain after treatment)

; How Tumors Use Meat to Grow; 98 % of American Diets Potassium Deficient; Best Treatment for Constipation; Breast Cancer & Alcohol: How Much Is Safe?

Your veterinarian will be able to explain how the specific tumor in your animal is likely to respond to treatment and behave in the future.

When ultrasound is used to measure the tumor size and to determine how well the treatment is working over time, it is critical to use a standardized ultrasound protocol.

Find out the symptoms of dog tumors, how to determine if they're cancer and your options for treatment.

Like the treatment for skin cancer, the prognosis varies significantly depending on the type of tumor and how advanced the disease is.

Conventional treatment for skin cancer depends on the type of tumor and how advanced the disease is at the time of diagnosis.

When we find a tumor on your pet we will be sure and go over how we need to determine an accurate diagnosis and all of the options for treatment so you can make the best choice in your pet's care.

Recent evidence provides essential clues into how these tumors grow and progress, generating new ideas for treatment approaches.