Sentences with phrase «how condensin»

By combining the fission yeast, mouse, and human systems with the latest genomic, genetic, cell biological, and biochemical approaches, we seek to determine how condensin and cohesin organize the functional 3D genome structures and participate in various biological processes, including transcriptional regulation and chromosomal dynamics, and how they contribute to oncogenic processes.

This video shows how a condensin protein (in red) binds to DNA (in green) and gradually extrudes a DNA loop over time.

Artist's impression of how a condensin protein complex extrudes a loop of DNA for the spatial organization of chromosomes.

Not exact matches

Researchers from the Kavli Institute of Nanoscience at Delft University and EMBL Heidelberg now managed for the first time to isolate and film the process, and witnessed — in real time — how a single protein complex called condensin reels in DNA to extrude a loop.

For many years, it has been clear that a protein complex called «condensin» plays a key role, but until now, biologists were divided on exactly how.