Sentences with phrase «huprot microarrays»

Natera uses a SNP microarray from Ilumina with a proprietary technology called Parental Support ™, which tests all 24 chromosomes and delivers results that are typically > 99 % accurate.

We also found that RNA sequencing yields superior results compared to microarray experiments.

In the microarray experiment, the range in relative abundances of the 500 most highly expressed genes is very narrow (Figure 1 inset), especially in contrast to RNA - Seq technology (Figure 1).

Given that a few abundant transcripts dominate the milk fat layer transcriptome during mature lactation, we suspected that microarray technology, in which high abundance transcripts saturate the signal, would be particularly handicapped in this biological context.

Other labs have used DNA microarray analysis to characterize gene expression changes in this model.

However, microarray analysis is only capable of measuring the status of known transcripts, and expression of low - abundance mRNAs is often not detected by the hybridization - based approach.

The panel can be used as a tool kit for screening and profiling of functional lncRNAs, or as an accurate quantification to validate functional lncRNAs in microarray or RNA - sequencing data.

Larger biomarker signatures can be detected with technology from CDI Laboratories, which offers microarrays of functional human proteins (over 20,000 on a single array) to test the antibodies present in human liquid biopsy samples, such as blood, serum, plasma, CSF, or tissue lysates.

The large microarrays are also well suited for finding new biomarkers.

Eager to sort through the pile of curriculum vitae's on his desk, Rudnicki is particularly looking for molecular geneticists working on different stem cell systems; scientists with genomics bents like proteomics, microarray analysis, and bioinformatics; and a couple of clinician scientists.

The technology for genome - wide profiling using microarrays was newly available, and with it came tremendous excitement, parallel to the mapping of the human genome.

«Microarrays are becoming practical tools,» Hackett said.

The foil - based measuring chip uses the microarray analysis platform MCR of the Munich company GWK GmbH.

My role there involved technology development for microarray - based genetic analysis.

Whether you are studying the expression of thousands of genes simultaneously using DNA microarrays, or the interaction of multiple molecules to understand intercellular signalling, the skills that will help you understand your findings are statistics, computational techniques, and modelling — so all you really need is a mathematician.

Therefore, before publication, large data sets (including microarray data, protein or DNA sequences, atomic coordinates or electron microscopy maps for molecular and macromolecular structures, and climate data) must be deposited in an approved database and an accession number or a specific access address must be included in the published paper.

There are and will continue to be jobs at companies that develop instruments and kits, such as microarrays, reagents, expression kits, and other supplies to fuel research programs.

The scientists then scanned the samples using microarray technology, which cuts genetic material into segments to provide a snapshot of which genes are active and which are asleep inside the cells.

This study, published in the journal Microarrays, shows that lack of SOST in the bone microenvironment promotes the expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.

Headquartered in San Diego, California, Illumina develops microarray technologies used in large - scale analysis of genetic variation and function.

The original microarray data are publicly available, he notes.

In contrast, when the OncoFinder algorithm is applied to the data, a clear correlation between next generation sequencing and microarray gene expression datasets was seen.

Last July, Perls and Sebastiani told Science that they were unaware of problems in the microarrays and were working hard to verify their results.

On a study funded by the National Science Foundation and Agilent Technologies, researchers employed spatial light interference microscopy (SLIM), a label - free method, to perform localized measurements of light scattering in prostatectomy tissue microarrays.

He worked there for 3 years, continuing his research on telomeres and pioneering the microarray techniques that form the basis of his international reputation.

As ICREA Prof. at ICFO Valerio Pruneri comments «the device means a major step forward for light microscopy techniques, especially for microarray platforms since it could definitely be used as a point - of - care tool in the diagnosis and treatment of major diseases such as Sepsis, a critical area where fast and accurate results can translate into life changing health outcomes for individuals.

Hughes's winning research proposed using microarray techniques to compare the genomes of a variety of vertebrate animals to test for common regulatory elements that determine gene expression.

Gene microarrays, which measure expression of dozens of genes at once, can be fickle and supply inconsistent results.

The Emory team used high density microarrays to probe more than 900,000 sites across the human genome to detect structural variation, including deletions or duplications of DNA.

They work on microarray - based gene sensors for analyzing nucleic acids quickly and cheaply.

One of these, his most influential, outlines his original use of microarray expression profiles as a phenotypic footprint for gene function.

The University Health Network (UHN) Microarray Centre (MAC) is a leader in microarray technology.

Microarrays have revolutionised functional genomics for biologists in much the same way as the microprocessor revolutionised the world of computing science.

DNA microarrays consist of thousands of spots contained on a single 1 x 3 inch glass slide, each spot representing a different gene.

Working at a microarray core facility is not where many of us thought we would be today, simply because microarrays were not as popular (or even around!)

The researchers then used microarray analysis and pre-clinical animal assays to identify two predominant glioblastoma subtypes, proneural and mesenchymal.

Large - scale methods of probing samples, such as DNA sequencing, microarrays, and automated gene - function studies, are filling new databases to the brim.

So it is also a good idea for biologists interested in pursuing a career in the microarray / biotechnology field to be computer savvy and have a working knowledge of statistics.

Microarrays are becoming a more commonly used tool in fields ranging from agriculture to zoology.

We ship over 1500 microarrays each month and provide training and support to over 280 academic labs on five continents.

In the relatively young field of microarrays, technical positions are never mundane or boring, because there are always opportunities to evaluate and refine new techniques and protocols as they become available.

ONE OF THE FIRST THINGS MIKOVITS DID was to employ a microarray — a small tray seeded with DNA from nearly every known virus — to flag viral DNA in human white blood cells.

To date, we have produced over 40,000 microarrays, with 20,000 shipped in the last year alone.

Microarrays are a perfect example of a convergence technology where multidisciplinary fields are required to make the technology a reality and to cause it to evolve.

As microarray technologies continue to develop, the chemistry underlying the biology will increasingly come to the forefront.

The University Health Network's Microarray Centre was established as part of a consortium of research institutions in Toronto.

However, the applications of microarrays also extend beyond the boundaries of basic biology into diagnostics, environmental monitoring, and pharmacology.

We currently produce DNA microarrays representing the yeast, mouse, and human genomes (the yeast microarray has over 6000 yeast genes, the mouse microarray has over 15,000 mouse genes, and the two human microarrays have 1700 genes and over 19,000 genes).

Production Group: Focuses its efforts on producing microarrays and refining manufacturing techniques.

In addition, pharmaceutical companies are now using microarrays to expedite the drug discovery process.