On Capitol Hill last week, Weinberg, an expert in the molecular biology of cancer, pointed out to the Congressional Biomedical Research Caucus that the major advances in understanding
human cancer genetics had come, not from studying breast tissue, but from studying cow warts, worm vulvas, fruitfly retinas, and a chicken virus.
In addition, the researchers examined neuroligin - 3 data from The Cancer Genome Atlas, a large public database of
human cancer genetics.
Not exact matches
The U.S. National Institutes of Health (NIH) has made major investments in network approaches in many areas, including
cancer biology, cardiovascular and metabolic diseases, neurophysiology, and
human genetics and genomics.
With an M.A. in
human genetics and molecular biology from Johns Hopkins University School of Medicine and a B.S. in biochemistry from New Mexico State University, Cordova has held research internships at those institutions as well as at the Fred Hutchinson
Cancer Research Center and at the University of Texas - Houston.
His research interests include the molecular underpinnings of cervical
cancer (including developing genetic screens), the identification of the genetic determinants of quantitative traits in
humans, and the application of massively parallel sequencing technology for understanding the
genetics of complex disease.
Her research is both translational and clinical in nature and centers on the
human genetics of healthy skin aging and diseases related to aging skin, including new treatments for advanced basal cell skin
cancers.
The study was led by Guoping Fan, professor of
human genetics and molecular biology and member of both the Jonsson Comprehensive
Cancer Center and the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research.
Physiological similarities between dogs and
humans, and conserved
genetics between some dog and
human cancers, can allow pet dogs to serve as useful models for studying new
cancer drugs, he said.
The MGH Research Institute conducts the largest hospital - based research program in the nation, with an annual research budget of more than $ 800 million and major research centers in HIV / AIDS, cardiovascular research,
cancer, computational and integrative biology, cutaneous biology,
human genetics, medical imaging, neurodegenerative disorders, regenerative medicine, reproductive biology, systems biology, photomedicine and transplantation biology.
Using mouse models that replicate the complexity of
human hepatocellular carcinoma
genetics, he is working on unravelling the mechanisms of regeneration and
cancer development in the liver.
CSHL is a private, non-profit research and education institution dedicated to exploring molecular biology and
genetics in order to advance the understanding and ability to diagnose and treat
cancers, neurological diseases, and other causes of
human suffering.
In addition to the inherited breast and ovarian
cancer, her research interests include
genetics of hearing loss, the genetic bases of schizophrenia,
genetics of systemic lupus erythematosus, and
human genetic diversity and evolution.
As Director of Cold Spring Harbor Laboratory (CSHL) from 1968 to 1994, he was a driving force behind creation of the Laboratory's
cancer genetics and neuroscience programs and played a seminal role in organizing the
Human Genome Project.
Reykjavik, ICELAND, September 14, 2008 — Scientists at deCODE
genetics (Nasdaq: DCGN) and colleagues at Radboud University Medical Center in the Netherlands today report the discovery of two common single - letter variants in the
human genome (SNPs) that confer increased risk of urinary bladder
cancer.
Multimedia Resources include educational websites, videos, and apps, which cover basic heredity, genetic disorders, eugenics, the discovery of the structure of DNA, the
human genome,
cancer, neurobiology, plant
genetics, RNA interference, epigenetics, and bioinformatics.
And we can also use what we know about the
genetics of the
human cancer to make mutations in normal cells, and see how different mutations drive invasion.»
December 17, 2013
Cancer genetics pioneer Janet Rowley, 1925 - 2013 A pioneer in connecting the development of cancer with genetic abnormalities, Janet D. Rowley, MD, the Blum - Riese Distinguished Service Professor of Medicine, Molecular Genetics & Cell Biology and Human Genetics at the University of Chicago, died from complications of ovarian cancer on December, 17, 2013, at her
Cancer genetics pioneer Janet Rowley, 1925 - 2013 A pioneer in connecting the development of
cancer with genetic abnormalities, Janet D. Rowley, MD, the Blum - Riese Distinguished Service Professor of Medicine, Molecular Genetics & Cell Biology and Human Genetics at the University of Chicago, died from complications of ovarian cancer on December, 17, 2013, at her
cancer with genetic abnormalities, Janet D. Rowley, MD, the Blum - Riese Distinguished Service Professor of Medicine, Molecular
Genetics & Cell Biology and
Human Genetics at the University of Chicago, died from complications of ovarian
cancer on December, 17, 2013, at her
cancer on December, 17, 2013, at her home.
According to Ophir Klein, MD, PhD, the Charles J. Epstein Professor of
Human Genetics and chief of the Division of Medical
Genetics at UCSF, «We are looking forward to a close interaction between Dr. Rajkovic and our clinical
genetics faculty members in Pediatrics, Obstetrics, Internal Medicine and the
Cancer Center, as well as with our colleagues working on genetic diseases in other departments.
I am applying principles from physical and computational sciences to the study of biology to find patterns in these interactions, to obtain insight into population
genetics,
human evolution, and diseases including
cancer.
Dr. Chung directs NIH funded research programs in
human genetics of obesity, breast
cancer, pulmonary hypertension, and birth defects including congenital diaphragmatic hernia and congenital heart disease.
Recent advances in our knowledge of
human genetics have enabled us to consider new approaches to how we treat
cancer.
At the same time, we will integrate today's discovery into the prostate
cancer module in our personal genome analysis service deCODEme ™, enabling our subscribers to stay abreast of how the latest discoveries in
human genetics may relate to their genome,» said Kari Stefansson, CEO of deCODE.
Laboratory activities minimally include performing a lab - based patient - oriented research project applicable to
cancer genomics, with an emphasis on mastering techniques commonly used within a
human genetics laboratory, such as PCR, gene sequencing, mutation analysis, western blots, and functional protein studies.
COSMIC, the Catalogue of Somatic Mutations in
Cancer (http://cancer.sanger.ac.uk) is a high - resolution resource for exploring targets and trends in the genetics of human c
Cancer (http://
cancer.sanger.ac.uk) is a high - resolution resource for exploring targets and trends in the genetics of human c
cancer.sanger.ac.uk) is a high - resolution resource for exploring targets and trends in the
genetics of
human cancercancer.
Massively parallel sequencing (next - generation sequencing) has revolutionized research in
cancer genetics and genomics [1] and enhanced our understanding of natural
human genetic variation [2], [3].
I encourage you to read the full CRUK Science Update Blog post «High - impact science: Hedgehogs, flies and skin
cancer — the story of vismodegib», it's an excellent example of how research on flies, rodents and a range of other organisms combined with studies of
cancer genetics in
humans to enabled the development of an innovative therapy.
High - throughput sequencing has fundamentally changed the field of
human genetics, particularly in how we study genetic diseases like
cancer.
Jason H. Moore, PhD, Third Century Professor, a professor of
genetics and of community and family medicine at Geisel, director of iQBS, and associate director of Norris Cotton
Cancer Center, said that «bacterial cells outnumber
human cells many-fold.
From our earliest research that established
cancer as a genetic disease to today's work in precision medicine, our unswerving focus on
genetics and genomics continues to generate advances that improve
human health.
Reykjavik, ICELAND, January 19, 2009 — Scientists at deCODE
genetics (Nasdaq: DCGN) and colleagues from the US and ten European countries today announced a long - awaited first in
cancer research: the discovery of common single - letter variations in the
human genome (SNPs) linked to susceptibility not of one, but several different types of
cancer, including those of lung, bladder, prostate, skin and cervix.
How research on the
genetics behind
cancers common to dogs and
humans became a commercial breed - test product is itself a unique story of technology transfer at the Center.
Ostrander, now chief of the
cancer genetics branch of the National
Human Genome Research Institute at the National Institutes of Health, said Wisdom Panel is a «very powerful tool for the millions of dog owners who buy their mixed - breed pets from a pound.
My primary research interests are
human genetics and
cancer genomics, and the content of my blog reflects that.
Articles cover the genetic basis of
human disease including germline
cancer genetics, the clinical manifestations of genetic disorders, applications of molecular
genetics to medical practice.