Recent evidence suggests that the health - promoting target of flavonoids is directed toward
the human gut bacterial metagenomes, and that these benefits have an evolutionary origin.
In vitro co-cultures of
human gut bacterial species as predicted from co-occurrence network analysis — Promi Das — PLOSone
Not exact matches
A 2012 study found that consuming maltodextrin increased
bacterial adhesion to
human intestinal epithelial cells and enhanced E. coli adhesion, which is associated with autoimmune disorders and dybiosis in your
gut.
Now, a team at the Wyss Institute for Biologically Inspired Engineering at Harvard University co-led by Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., and Wyss Core Faculty member James Collins, Ph.D., has leveraged the Institute's proprietary
human - organs - on - chips technology to microengineer a model of
human intestinal inflammation and
bacterial overgrowth in a
human -
gut - on - a-chip.
«Healthy
gut bacterial communities are known to benefit immune regulation, metabolism and potentially even the nervous system, so if cholera or other diarrheal diseases permanently impact the microbiota, there could be long - term effects on
human health,» explains Regina LaRocque, MD, MPH, of the Massachusetts General Hospital (MGH) Division of Infectious Diseases, co-senior author of the paper.
Regulatory issues must be addressed before moving to
human studies, Davies said, but the findings published in the August issue of the Journal of Clinical Investigation suggest that it may be possible to manipulate the
bacterial residents of the
gut — the
gut microbiota — to treat obesity and other chronic diseases.
By chemically removing the
gut microbiome in zebrafish in the lab and then repopulating the
gut with two to three
bacterial species, University of Oregon biologist Karen Guillemin has shown that certain microbes are especially skilled at suppressing the host immune system and preventing inflammation — a discovery she thinks may have implications for
human health.
Now, relationships between
gut bacterial species mirror the family tree of gorillas,
humans, bonobos and chimpanzees.
In a study, researchers found that pigs, which have
gut bacterial profiles and immune systems similar to
humans, also maintain two distinct colonic stem cell populations — ASCL - 2 and BMI - 1.
In addition, cohousing coprophagic mice harboring transplanted microbiota from discordant pairs provides an opportunity to determine which
bacterial taxa invade the
gut communities of cage mates, how invasion correlates with host phenotypes, and how invasion and microbial niche are affected by
human diets.
Since the
human body plays host to vast numbers of bacteria, particularly our
gut microbiome, this effectively means that there is a
bacterial war going on inside us.
It is present in soil and, just like E. coli, it can also be found in the
human gut, where a complex ecosystem of
bacterial inhabitants exists.
«We know from previous
human studies that changes in
gut bacterial composition correlate with the early development of type 1 diabetes, and that the interactions between
bacterial networks may be a contributing factor in why some people at risk for the disease develop type 1 diabetes and others don't,» said Jessica Dunne, Director of Discovery Research at JDRF, which funded the study.
Studies in
humans have also shown an association between T1D and the
bacterial composition of the
gut.
In many studies of
human subjects the question of interest centers on whether a biological factor (disease state, treatment, host genotype etc.) results in a measurable difference on a
gut bacterial community against the background of the naturally occurring differences among
humans.
«Collinsella provencensis» sp. nov., «Parabacteroides bouchesdurhonensis» sp. nov., and «Sutterella seckii» sp. nov., three new
bacterial species identified from
human gut microbiota — Niokhor Dione — New Microbes and New Infections
Differential
bacterial capture and transport preferences facilitate co-growth on dietary xylan in the
human gut
Two
bacterial species that inhabit the
human gut activate immune cells to boost the effectiveness of a commonly prescribed anticancer drug, researchers report Oct..
Bacterial growth, flow, and mixing shape
human gut microbiota density and composition — Markus Arnoldini — Gut Micro
gut microbiota density and composition — Markus Arnoldini —
Gut Micro
Gut Microbes
The lack of knowledge in this area stems from the fact that, as yet, the conditions required to culture most of the
bacterial species resident in the
human gut are not understood.
We investigated the distal
gut bacterial communities of three healthy
humans before and after treatment with ciprofloxacin, obtaining more than 7,000 full - length rRNA sequences and over 900,000 pyrosequencing reads from two hypervariable regions of the rRNA gene.
This intelligent
bacterial ecosystem in your
gut makes up the majority of your immune system, and your body actually contains 10 times more
bacterial cells than
human cells!
Just like we realize now that our
gut isn't just
human cells but actually contains more
bacterial cells than our own cells, we have to realize that our health depends on what's outside our own bodies — like our environment and the community of people we surround ourselves with.
The
human gut contains 10 times more bacteria than all the
human cells in the entire body, with over 400 known diverse
bacterial species.
It makes perfect sense that
gut health would have such a dramatic impact on all aspects of health, since the body has more
bacterial cells in the
gut than it does
human cells in the entire body.
Shows you how your
bacterial strains and levels compare to the National Institutes of Health's
Human Microbiome Project data on
gut bacterial strains
Human chronic heart failure patients have also been shown to have reduced
gut bacterial diversity and lower abundance of key
bacterial genera (20).
It's said that
humans are only 10 %
human; we have 10 trillion
human cells and 100 trillion
bacterial cells, many of which reside in our
gut.
Hazuda points out that a number of
human and animal studies indicate that faux sweeteners may damage beneficial intestinal
bacterial in the
gut.
If you routinely give your dog
human gas reduction products, acidic levels can be depleted, leaving your dog's
gut with inadequate protection against
bacterial infection.
Proposed causes for
human IBD include defective immunoregulation of the
gut - associated lymphoid tissue that may be precipitated by permeability defects, 14 infectious and parasitic agents, 15,16 and dietary allergies.13, 17 There is provocative evidence from clinical observations and animal models to incriminate normal luminal bacteria or
bacterial products in the initiation and perpetuation of canine IBD.18, 19 The clinical response to hypoallergenic or elimination diets suggest that dietary factors may influence the pathogenesis of canine IBD.8 - 11 The term «hypoallergenic» refers to a diet that is generally free of additives and preservatives, and contains a hydrolyzed protein source.
The normal
bacterial flora of the
human gut is different from that of cats.