Major Symposium C: New Regulatory Concepts from
Human Immunology Studies Ballroom D Chairs: Bana Jabri, Univ. of Chicago Michael J. Lenardo, NIAID, NIH
Major Symposium C: New Regulatory Concepts from
Human Immunology Studies Chairs: Bana Jabri, Univ. of Chicago Michael J. Lenardo, NIAID, NIH
Not exact matches
In a new
study published in Mucosal
Immunology, researchers from Brigham and Women's Hospital (BWH) report that
human breast milk serves as a reservoir for bio-molecules that help to resolve inflammation and combat infection.
A new
study published in the journal Mucosal
Immunology discovered a «reservoir» of bio-molecules in
human milk that heal infection and wounds, reduce pain and calm inflammation.
Hackett said, «
Studies of
human immunology are usually not the first choice for research in basic
immunology, but it is very important now to understand how
humans differ from animal models.»
Now, a
study published online April 27th, in the Journal of
Immunology, confirms that the cytokine GM - CSF (Granulocyte macrophage colony - stimulating factor) likely plays an important role in
human disease and offers a new explanation for why the MS treatment interferon - Beta (INF - β) is often effective at reducing MS attacks.
The probability of this virus surviving and infecting a
human is so low — it is as if Topham and lead
study author, Marta Lopez de Diego, Ph.D., research assistant professor of Microbiology and
Immunology, found a needle in a haystack.
The team led by Dr Rubén López — of the UAB's Department of Cell Biology, Physiology and
Immunology and Institute of Neuroscience, and the Centre for Networked Biomedical Research in Neurodegenerative Diseases (CIBERNED)-- used a genetically modified mouse that produces the
human form of IL - 37 to
study the function of this protein.
«Since it's impossible to predict which of these agents will cause the next epidemic, it would be ideal to develop a single therapy that could treat or prevent infection caused by any known ebolavirus,» says
study co-leader Zachary A. Bornholdt, Ph.D., director of antibody discovery at Mapp Biopharmaceutical, Inc. «Our discovery and characterization of broadly neutralizing
human antibodies is an important step toward that goal,» adds
study co-leader, Kartik Chandran, Ph.D., professor of microbiology &
immunology at Albert Einstein College of Medicine.
To facilitate understanding of the immune system by showcasing innovative advances in the expanding field of
immunology, drawing from
studies in all organisms and model systems including
humans.
«If our findings are confirmed in
human studies, the new drug regimens that we have identified should dramatically shorten the time needed to treat tuberculosis,» said Dr. Marcus Horwitz, a senior author on the research and a distinguished professor of medicine and microbiology,
immunology and molecular genetics at the UCLA David Geffen School of Medicine.
Watkins and Dennis Burton, Ph.D., chairman and professor of the Department of
Immunology & Microbiology at the Scripps Research Institute, led the collaborative international
study, «Neutralizing
Human Monoclonal Antibodies Prevents Zika Virus Infection in Macaques,» published recently in Science Translational Medicine.
The findings, published online in advance of print in the The Journal of
Immunology, show promise for
studies investigating the effects of vitamin E and infection in
humans.
The second laboratory continues to focus attention on transplantation immunobiology in mouse models and translational
studies of
human immunology in transplant recipients.
Finally, I wanted to
study disease more in depth, with a particular focus on
human Immunology.
«These are very promising findings and, as the first
study to demonstrate protection from Zika in the pregnancy setting, are an important development in our efforts to combat Zika virus,» said Michael Diamond, M.D., Ph.D., Professor, Departments of Medicine, Molecular Microbiology, Pathology &
Immunology, and Associate Director, Center for
Human Immunology and Immunotherapy Program at Washington University School of Medicine, and a lead author on the Cell paper.
During her residency in
Human Genetics at the University of Bonn she pursued her research interest both in immunology and human genetics by investigating expression quantitative trait loci (eQTLs), which underpin innate immune responses, and provide mechanistic insights to complement genome - wide association stu
Human Genetics at the University of Bonn she pursued her research interest both in
immunology and
human genetics by investigating expression quantitative trait loci (eQTLs), which underpin innate immune responses, and provide mechanistic insights to complement genome - wide association stu
human genetics by investigating expression quantitative trait loci (eQTLs), which underpin innate immune responses, and provide mechanistic insights to complement genome - wide association
studies.
«If we delay the start of the rejection response, it should be milder and more easily controlled and lead to less late rejection,» said Pober, who is a co-author of the
study and also director of Yale's
Human and Translational
Immunology program.
For custom gene expression projects the Genomics Core has a platform that uses sets of
human and mouse custom arrays whose probe content is aimed at gene expression
studies in the areas of cancer,
immunology and other complex diseases.
In their latest
study, researchers at La Jolla Institute for Allergy and
Immunology (LJI) used single - cell transcriptome analysis to identify a hitherto unknown precursor for a poorly understood subgroup of killer T cells that is primarily found in
humans with chronic viral infections.
The
study was funded in part by the La Jolla Institute for Allergy and
Immunology, the National Institute of Allergy and Infectious Diseases, the National Institutes of Health and the Department of Health and
Human Services Grant R37 AI71922 and under Contracts NO1 - AI - 25496, NO1 - AI - 25482, HHSN272200900052C, HHSN2722010000521, 1UM1AI114271 - 01, and UM2AI117870.
Sujan Shresta, Ph.D., and her team
study the
immunology and virology of dengue virus (DENV) and Zika virus (ZIKV), both globally important mosquito - borne
human pathogens.
The department of
Immunology has a long tradition in
studies of innate, mucosal, and placental, as well as classical acquired immune responses, in both
human and experimental mouse models.
That's as little as one - tenth of the intake among the world's dwindling hunter - gatherer and rural agrarian populations, whose living conditions and dietary intake presumably most closely resemble those of our common
human ancestors, said Justin Sonnenburg, PhD, associate professor of microbiology and
immunology and senior author of a
study published Jan. 13 in Nature.