Sentences with phrase «human ageing genomic»
Human ageing genomic resources: integrated databases and tools for the biology and genetics of ageing.
http://www.nature.com/ Not exact matches
Using advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and cell therapy technologies, HLI is building the world's most comprehensive database of human genotypes and phenotypes as a basis for a variety of commercialization opportunities to help solve aging related disease and human biological decline.
In the last four years, the U.S. - based Human Microbiome Project used genomic analysis to identify bacteria, viruses, fungi, archaea, and protozoa in the noses, gums, tonsils, genital tracts, and guts of 242 healthy Americans between the ages of 18 and 40; more than 11,000 samples were taken in all.
For Neandertal genomics to come into its own, however, Pääbo, Rubin, and others must demonstrate that their sequences are real and not a mosaic of errors due to degradation that occurs as DNA ages, sequencing mistakes, or contamination from modern humans who have handled the fossils, says genomicist Stephan Schuster of Pennsylvania State University in State College.
«So perhaps in this age of cancer genomics showing how diverse and heterogenous human cancer is, we should be focusing on the common effects that different mutations lead to,» he says.
The Cancer, Ageing and Somatic Mutation Programme encompasses three Projects that respectively cover the genomics of human cancers; functional analysis of the cancer genome using a range of in vitro and in vivo model systems; and the characterisation of somatic mutations in development and adult homeostasis in health and disease.
Using advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and cell therapy technologies, HLI is building the world's most comprehensive database of human genotypes and phenotypes as a basis for a variety of commercialization opportunities to help solve aging related disease and human biological decline.
HLI is using genomic sequencing, the human microbiome, proteomics and advanced computing to tackle aging - related human diseases.
Ageing research and more generally the study of the functional basis of human diseases profit enormously from the large - scale approaches and resources in mouse functional genomics: systematic targeted mutation of the mouse genome, systemic phenotyping in mouse clinics, and the archiving and distribution of the mouse resources in public repositories.
According to JCVI President Karen Nelson, Ph.D., «JCVI's extensive knowledge in human genomics, comparative genomics and the human microbiome, coupled with the clinical expertise of WCHN, should result in new insights into healthy aging.
The HDCA programme will create genomic reference maps of all the cells that are important for human development, which will revolutionise our understanding of health and disease, from miscarriages and children's developmental disorders, through to cancer and ageing.