Human brain cells derived from iPSCs offer great potential for drug screening.
Not exact matches
«
Brain scientists have invented, established and patented a method to obtain long - living
cell lines
derived from fungiform taste papillae of the
human tongue.
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in
human embryonic kidney
cells,
brain cell samples and neurons
derived from the stem
cells of healthy people and those with spinal muscular atrophy type I and II.
By assessing the survival of the
cells that engulf the particles and measuring the levels of red or green light that they emitted, the researchers determined which formulation of particles performed best, then tested that formulation in mice with
human brain cancer
derived from their patients.
Human neural stem
cells are
derived via fluorescence - activated
cell sorting (FACS) from donated fetal
brain tissue.
Twelve months after being injected with
brain -
derived stem
cells near the injury site, one of the three
human participants has regained some feeling in the lowest portions of his spine.
Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor
cells derived from embryonic stem
cells and from
human fetal
brain tissue can successfully create myelin sheaths around nerve
cells, sometimes leading to dramatic improvements in symptoms.
Neural stem
cell lines
derived from
human fetal
brain tissue achieved the same feats, the researchers report in the October issue of Nature Neuroscience.
Scientists at the University of Luxembourg have succeeded in turning
human stem
cells derived from skin samples into tiny, 3 - D,
brain - like cultures that behave very similarly to
cells in the
human midbrain.
«Inhibition of the EZH2 pathway slows growth of tumors in mouse
brain derived from glioma stem
cells from the enhancing margin of
human tumors.
Past clinical trials of stem
cell therapies for chronic stroke patients used
cells derived from tumors in
humans and
brain tissue from fetal pigs.
Here I want to show you a time lapse movie of a
human brain pericyte -
derived cell undergoing neuronal reprogramming.
Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of
human material, such as postmortem
brains, primary
cell systems, and neural
cell populations generated from patients» - or healthy individuals» -
derived induced pluripotent stem
cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.
NeuroStemcell is focused on the identification and systematic comparison of progenitor
cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from
human embryonic stem (ES)
cells, from Neural Stem (NS)
cells derived from ES
cells or fetal
brain, from induced Pluripotent Stem (iPS)
cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate
cells in appropriate animals models.
Jason Lee / Reuters In the next few months, surgeons in the Chinese city of Zhengzhou will carefully drill through the skulls of people with Parkinson's disease and inject 4 million immature neurons
derived from
human embryonic stem
cells into their
brains.
Human embryonic stem
cell -
derived neurons establish region - specific, long - range projections in theadult
brain
The mini
brains are
derived from
human stem
cells thus, may be used instead of animal models to test new drugs, revolutionizing the way lab experiments work.