Human drugs like NSAIDs (non-steroidal anti-inflammatory drugs), antihistamines, antidepressants and diabetic medications can all cause seizures in pets.
Not exact matches
More common and larger - scale cyber-attacks (from Sony pictures to Spanish renewable energy companies) are yet another example of this unprecedented «communication» flow; just as growth of the dark web has allowed for more effective connections in illegal activities —
drug trade,
human trafficking, and the
like.
She points to a few issues on which there's a «clear path,»
like stamping out tuberculosis in Inuit communities, which she says is a matter of putting in place «the X-ray machines and the
human resources and the
drugs and the housing.»
Some,
like St. Augustine, have argued that many apparently antireligious activities — including drunkenness, carousing, promiscuous sex, harsh athletic training, committed political activism, incessant material consumption, and
drug addiction — actually represent deeply driven
human religious longings and searching, which happen to be misdirected quests for the true religious good.
Sure lets talk about «binder's of women» anything but the real issues
like the
human rights violations when we drop bombs on cities with unchecked drone power, spying on our own citizens, still waging war on our own population calling it a war on
drugs and turning us into a gulag state.
To Ken Margo: I am totally agree with you about this evil thing going around the earth... this evil minded people is there everywhere regardless of faith... that was not what i was trying to say... my point was to be able to recognize the One True God who is Unseen and who has no partners as He is not in need of any partners but we the creation is in need of Him... thats all... I wish I could do something to stop all these taking place around the earth... I think we
human fear the fed laws more than we fear the laws of our Creator, for example not to associate any partner with Him, taking the life of others,
drug dealing,
human trafficking, believing in hereafter and so on... I remember a story that I was talking with one of my friends... I was telling him look we all obey the law of the land so much
like for example when we drive and no one moves even an inch when there is a school bus stop to pick / drop kids as it is a fed laws but when it comes to the laws of our Creator, we don't care...
like having physical relationship outside of marriage and many more... then he said something nice... he said that its because we see the consequence of breaking the law of the land but we do not see the punishment of hereafter even though it is mentioned very details in Quran, it even gives pictures of hereafter....
Postwar Nazi Germany is full of
drug - taking young Nazis, implicitly just
like us that way, it makes them more
human.
I remember feeling
like a total bad ass for just giving birth to you sans
drugs, and feeling overwhelmed by the prospect of caring for your tiny
human self.
We know these
human bond substitutes as addictions... to substances
like alcohol or
drugs, social media, gambling, shopping, and any number of other compulsions.
Since sudden withdrawal of power,
like the abrupt withdrawal from
drugs, produces uncontrollable cravings, those who possess power, especially absolute power, are highly unlikely to give it up willingly, smoothly and without
human and material loss.
Nichols believes that when the initial dose of Flatliners failed to produce the ecstasy -
like euphoria the
human drug users were expecting, they upped their dosage — and kept upping it until it killed them.
The new
drug -
like compounds discovered by Vogel and her co-authors offer hope that using a computer - generated P - gp model, explained here http://bit.ly/1LVmR7a, developed to accurately mimic the physical, chemical and biological functions of the protein in the
human body, will speed up the
drug discovery process and work in real life as well.
«We've been targeting
human cells with therapeutics that modulate the way the cell makes lipids, and we
like to target the
human cell because it isn't likely to mutate and become resistant to the
drug.
The
drug -
like compounds can be modified and developed into medicines that target a protein in the
human body that is responsible for chemotherapy resistance in cancers, said biochemist Pia D. Vogel, lead author on the scientific paper reporting the discovery.
Like drug - addicted
humans, they also had fewer receptors for the reward chemical dopamine (Nature Neuroscience, DOI: 10.1038 / nn.2519).
«Computational models
like this one might one day be able to predict the clinical course of a disease or injury, as well as make it possible to do less expensive testing of experimental
drugs and interventions to see whether they are worth pursuing with
human trials,» he said.
Next, researchers would
like to study how the two -
drug approach works in
humans, although no clinical trials have yet been designed or scheduled.
Moreover, epalrestat, a
drug that inhibits AKR1B1 and is approved in Japan to treat peripheral neuropathies associated with diabetes, was similarly able to block the growth and metastasis of
human basal -
like breast cancer cells.
Ideally, this helps researchers design
drug compounds that perform similar functions but retain attributes needed for successful medicines,
like nontoxicity and the ability to travel through the
human body.
What I especially
like about working for UKHTB is that it offers a new challenge and is pioneering in an area that has the potential to benefit
human health through the enhanced development of new
drugs and diagnostic tools.
«We found that the more complex, dynamic culturing conditions (
like those used in this project) are necessary to accurately predict renal
drug toxicity in
human systems,» said Sakolish.
The team's screen yielded 53
drugs that block Ebola virus -
like particles from entering
human cells.
Because
human T cells don't have as many of these brakes, our cells are a hundred times more aggressive than those of chimps when faced with
drugs like TGN1412, which work by triggering the immune system.
«
Human -
like nose can sniff out contamination in drinking water: New technology could be used to detect
drugs at airports, test food quality and develop perfumes.»
In recent research published in the Journal of Biological Chemistry, Saint Louis University investigators report catching integrase, the part of retroviruses
like HIV that is responsible for insertion of the viral DNA into
human cell DNA, in the presence of a
drug designed to thwart it.
«The findings of adverse effects of BPA in
human tissue are highly relevant and should encourage agencies
like the Food &
Drug Administration to re-evaluate their policies in the near future.»
Developing
drugs that modulate genes
like Rev - Erbα could therefore help protect
human hearts during surgery.
A technique that involves genetically engineering brain cells so that they fire in the presence of certain
drugs has been used to treat an epilepsy -
like condition in rats, and it could soon be trialled in
humans.
Others speculated that,
like the malaria
drug chloroquine, artemisinin frustrates the removal of haem, a toxic byproduct formed during the parasite's consumption of
human hemoglobin.
Substance use disorders of highly addictive opioids
like heroin, fentanyl and oxycodone continue to skyrocket in the U.S. Intravenous opioid use disorders are a major contributor to the
drug overdoses that are the leading cause of injury death in the United States, according to the Department of Health and
Human Services.
Anderson and Valerie Grum - Tokars, a junior structural biologist on the team, developed a three - dimensional structure of
human p38 MAPK, enabling the chemists to design and synthesize novel
drug -
like small molecules that would disable it.
Because the Ebola virus -
like particles used for screening different
drugs in this study were not fully infectious, Level 4 was not required.The viral mini-genome generated modifies the Ebola virus to produce virus -
like particles that are no longer harmful to
humans.
«Based on our findings, we are highly motivated to bring a
drug -
like derivative of JQ1 forward as a new type of heart failure
drug for
humans,» Haldar says.
Further research on how serotonin works in the
human brain is needed, according to study author Dr. Toru Takumi, a senior team leader at the RIKEN Brain Science Institute in Japan, to determine whether
drugs like fluoxetine could offer similar potential to treat
humans with ASD.
Ross says that because the hyperactivity and decreased anxiety might be interpreted as «mania -
like» symptoms, the researchers fed the mice either lithium or valproic acid (an anti-seizure
drug, also used to treat mania) over a two week period, as is often done in
human therapeutic trials.
Like other parts of the GI tract grown by the researchers, the
human colon organoids also create a potential new platform for testing new
drugs before the start of clinical trials.
Tiny machines
like nanorockets are ideal candidates for
drug delivery in the
human body.
He says HGS was getting «diminishing returns» from its investment in TIGR since Venter had steered his outfit into sequencing organisms of little medical importance, and into
human genome sequencing, also of limited value for a company
like HGS that is interested in genes as
drug targets (not untranslated DNA that makes up most of the genome).
It is exciting that there is now evidence that brown fat can be useful in treating obesity in adult
humans, and that it can be activated by cold exposure or a
drug like mirabegron (18 April, p 32).
In response to similar concerns about
human studies, the U.S Food and
Drug Administration (FDA) in 2007 mandated that researchers conducting
human clinical trials preregister the details in an online database
like ClinicalTrials.gov.
Promote
human clinical trials of repurposed
drugs, in collaboration with medical centers (
like UC San Francisco) and pharmaceutical companies in the US and abroad.
Genetically engineered mice now act as robust engines for the generation of diverse repertoires of affinity - matured, fully -
human variable regions with intrinsic
drug -
like properties necessary for successful development including high potency, specificity, manufacturability, solubility and low risk of immunogenicity.
With such knowledge, it may be possible to stimulate these nerve cells by artificial means, for example by selective nicotine -
like drugs, to improve memory and learning in
humans.
How would this development (and whatever
drug or therapy they devise for
humans) move from the lab and into trials, without it taking decades,
like the author here proposes?
In recent years, researchers have developed so - called «senolytic»
drugs that wipe out senescent cells in aging mice and mouse models of age - related disease, exploiting the high dependence of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic
drugs have restored exercise capacity9 and formation of new blood and immune precursor cells11 in aging mice to near youthful norms, and prevented or treated mouse models of diseases of aging
like osteoarthritis, 12 fibrotic lung disease, 13 hair loss, 14 atherosclerosis, 15,16 and age - related diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with
human clinical trials expected to begin in 2019.
A striking example of this is MPP +, a well - established neurotoxin that specifically attacks the SNc dopaminergic neurons in lab mice, monkeys — and in
humans: MPP +'s parent compound, MPTP, has caused numerous cases of Parkinson's -
like syndrome in young people exposed to it in underground
drug labs, or via contaminated street
drugs.1
Of note today: An evaluation of multi-site
human microbiome temporal stability over six months; The impacts of 1,000 non-antibiotic
drugs on the in vitro gut microbiome; Caspase - 1 might modulate the relationship between stress, the gut microbiome, inflammation and depressive -
like behaviour in mice; And the impact of warming on the Antarctic soil microbiome
When researchers
like Gan find potential new
drugs, it's useful to test them on
human cells to increase the chances that they will benefit patients.
«Artificial sweeteners have positive reinforcing effects — meaning
humans will work for it,
like for other foods, alcohol, and even
drugs of abuse,» he says.
«
Human milk is a body fluid
like saliva, blood, or semen, so it can transmit infectious diseases,» says Keim — including HIV and hepatitis C and B. «
Human milk can also carry with it any
drugs or pharmaceuticals that donor might be taking,» she adds.