Dr. Jamel Chelly, Institut Cochin, Université Paris - Descartes, CNRS (UMR 8104), Paris, France, (
Human muscle diseases and cell banking)
Not exact matches
Stanozolol: This synthetic anabolic steroid istypically used to treat a rare immune
disease in
humans and to increaseappetite,
muscle mass and energy in animals — often horses recovering fromillness or injury.
Svendsen is more optimistic about his team's work involving
human tests of a novel stem cell approach to treat ALS, a degenerative motor neuron
disease in which cells that transmit messages from the brain and spinal cord to the
muscles wither or die.
In order to locate all gene switches, the Freiburg research team used modern sequencing methods to examine the entire genome — DNA, epigenetic markers and RNA — during the development, maturation and
disease of
human cardiac
muscle cells.
In a series of studies this year, molecular geneticists at the University of Pittsburgh School of Medicine used a harmless virus to ferry new genes through the bloodstream, across blood vessel walls, and into almost every
muscle cell in the bodies of hamsters bred to have
human genetic
diseases.
In addition to determining that
humans use chemosignals to attract one another, the findings could one day be used to create new therapies to correct hormone imbalances — most notably alternatives to cortisol replacement, which is used in treat maladies such as Addison's
disease (in which the adrenal glands fail to pump out enough cortisol, causing
muscle weakness, weight loss and low blood pressure).
Because myostatin normally acts to limit
muscle growth, there has been considerable interest in targeting this pathway to attempt to enhance
muscle growth in
human patients with
muscle wasting and
muscle degenerative
diseases.
In order to locate all gene switches, the Freiburg research team used modern sequencing methods to examine the entire genome - DNA, epigenetic markers and RNA - during the development, maturation and
disease of
human cardiac
muscle cells.
This is the first study to show that the repeat genome can be effectively targeted using CRISPR technology, the first use of CRISPR inhibition for a
human disease, and the first use of CRISPR technology in primary
human muscle cells.
Most of the study's experiments were done in the roundworm C. elegans, which have an SMN gene and motor neurons — those that connect to
muscle — that are very similar to
humans, making them valuable models in which to study this
disease.
Epidemiological surveys in
humans indicate that
muscle aging influences the progression of several age - related
diseases in other tissues.
Epidemiological surveys in
humans indicate that
muscle aging influences the progression of several age - related
diseases in other tissues... >> MORE
The researchers then successfully prodded what they call keratinocyte - derived iPS cells or KiPS cells to distinguish them from fibroblast - derived iPS cells into becoming all the cell types in the
human body, including heart
muscle cells and dopamine - producing neurons, which are affected by Parkinson's
disease.
Plenary Lecture:
Muscle Sympathetic Reflexes in
Humans Lawrence I. Sinoway, Director of the Penn State Hershey Heart and Vascular Institute, leads the discussion on the exercise pressor reflex and how it is altered in cardiovascular
disease, such as heart failure..
High - resolution maps of enhancer - promoter interactions in rare primary
human T cell subsets and coronary artery smooth
muscle cells link variants associated with autoimmune and cardiovascular
diseases to target genes.
1) Phytonutrients: * Occur naturally in fruits and vegetables * Promote the function of the immune system * Help fight off viruses as well as reduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular
disease 2) Enzymes: * Responsible for metabolic processes that occur within a cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of
muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart
disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all
human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones and teeth
In the 1960's and 1970's in China, government sponsored research discovered a form of cardiac
muscle degeneration in
humans called Keshan
disease occurring in the Keshan province noted for low selenium levels in its soil.
«The chronic exposure to high levels of ROS is associated with the development and / or progression of pathophysiological processes, and implicated in an increasing number of
human diseases, such as cardiovascular, metabolic, inflammatory and neurogenerative
diseases, cancer as well as
muscle atrophy and the ageing process.»
In certain delta frequencies the brain releases many highly beneficial substances, including
human growth hormone, which we ordinarily make in decreasing quantities as we get older — resulting in many aging symptoms including loss of
muscle tone, increased weight gain, loss of stamina, and many
diseases associated with aging.
During routine testing, several of the zoo's lorikeets were found to have the
disease, which is a pneumonia - like illness that can cause fever, chills, headache, muscles aches, and a dry cough in humans, per the U.S. Centers for Disease Control and Prevention
disease, which is a pneumonia - like illness that can cause fever, chills, headache,
muscles aches, and a dry cough in
humans, per the U.S. Centers for
Disease Control and Prevention
Disease Control and Prevention (CDC).
L - carnitine deficiency has been associated with heart
disease in both
humans and dogs and supplementation with the vitamin - like chemical suggests a beneficial affect for dogs with cardiac arrhythmias and thickening of the heart
muscle.
«This also provides an extraordinary advancement to the study of
human heart
diseases resulting from electrical conduction defects and the resulting heart
muscle changes that occur.»
Heart
diseases in pets include congenital heart
diseases (from birth), cardiomyopathy (
disease of the heart
muscle), valvular heart
disease (
disease of the heart valves) and, just like in
humans, congestive heart failure.