This is what makes the return of therapeutic cloning such a gripping plot twist (see «
Human stem cells made using Dolly cloning technique «-RRB-.
Not exact matches
Scientists looking for new methods to
make human tissue have successfully used cloning technology to create embryonic
stem cells from skin
cells.
Proponents of
human cloning assert that this is the only method of producing pluripotent
stem cells with the same genetic
make - up as adult patients.
We referred to the news that these
cells, called induced pluripotent
stem cells (iPSCs), could be
made from
human skin....
Frankenbunnies Embryos
made by Chinese researchers who fused
human skin
cells with rabbit eggs, hoping to create a source of
stem cells.
To
make the HSCs, the Harvard group used
human skin
cells to create induced pluripotent
stem cells (iPSCs), adult
cells researchers genetically reprogram to an embryonic -
stem -
cell state, where they can grow into any kind of
cell.
A new type of
human stem cell, never seen in nature, should be better at
making replacement organs than existing
stem cells
Trials of
cells made from
human embryonic
stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic
stem cells have been used in the treatment of major lethal diseases.
«Today's findings exemplify the many advances we've
made in using CRISPR - Cas9 and
human induced pluripotent
stem cell technologies and the amazing discoveries that have resulted,» said Hideyuki Okano, MD, PhD, of the Keio University School of Medicine in Tokyo, Japan.
But the factor that may
make the discovery very significant is that umbilical cord blood can be saved, stored and multiplied without any of the ethical dilemmas facing embryonic
stem cell use, which are derived from
human fetuses.
The patch is
made of eye
cells made from
human embryonic
stem cells, and it has been designed for treating the «dry» form of macular degeneration, which accounts for 90 per cent of all cases, and affects 1.7 million people in the US.
Woo Suk Hwang, the veterinarian who
made headlines when he cloned
human stem cells last year, announced in May that he and his colleagues had
made stem cells tailored for different patients.
Geron, the biotech wunderkind, last
made big news in November 1998 when scientists they funded — James A. Thomson of the University of Wisconsin and John D. Gearhart of Johns Hopkins — independently isolated two sorts of so - called
human pluripotent
stem cells.
In
humans, the goal of SCNT is «nonreproductive cloning» —
making embryos, then removing
stem cells from the embryo and cultivating them to grow into tissues that could cure diseases, replace organs and heal injuries.
Twelve people with Stargardt's macular dystrophy will be treated with retinal
cells made from
human embryonic
stem cells (hESCs) in the hope of improving, or at least halting loss of sight.
«It's taken years of trial and error,
making educated guesses and taking baby steps to finally produce functioning
human muscle from pluripotent
stem cells,» said Lingjun Rao, a postdoctoral researcher in Bursac's laboratory and first author of the study.
Scientists, with practice, have now been able to
make nuclear transfer nearly routine to produce cattle, cats, mice, sheep, goats, pigs, and — as a Korean team announced in May — even
human embryonic
stem (ES)
cells.
The results obtained by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in
Human and Molecular Biology show, for the first time, using mice, that pluripotent
stem cells differentiated into cortical neurons
make it possible to reestablish damaged adult cortical circuits, both neuroanatomically and functionally.
Faith and the embryo Biochemist Paul Berg suggests in April's Discover Dialogue [«Bio Brain Backs
Stem Cells»] that only religious faith
makes the judgment that the destruction of a
human embryo destroys a
human individual.
And now we're going to look through their bodies, and we're going to look to see what parts of the body the
human embryonic
stem cell makes.
The recipe, described in Nature, allows
human pluripotent
stem cells to spontaneously attempt to assemble into a tiny approximation of a whole brain by
making whatever brain structures the
stem cells choose.
Methods for
making bits of brainlike tissue tap the innate tendency of
human pluripotent
stem cells to form neural tissue.
«By identifying the signals that instruct mouse progenitor
cells to become
cells that
make tubes and later insulin - producing beta
cells, we can transfer this knowledge to
human stem cells to more robustly make beta cells, says Professor and Head of Department Henrik Semb from the Novo Nordisk Foundation Center for Stem Cell Biology at the Faculty of Health and Medical Scien
stem cells to more robustly
make beta
cells, says Professor and Head of Department Henrik Semb from the Novo Nordisk Foundation Center for
Stem Cell Biology at the Faculty of Health and Medical Scien
Stem Cell Biology at the Faculty of Health and Medical Sciences.
The study developed a new in vitro system
made from bone marrow
stem cells and studied what would happen if its ambient temperature fell below 37 °C (the natural temperature of the
human body).
«Even if we can
make other
cells to look like embryonic
stem cells, ES
cells allow you to investigate unique aspects of
human embryonic development.»
• News from the World of Adult -
Stem Cell Research • At the University of California at Los Angeles, Marc Hedrick's team used
human adult fat
cells extracted during liposuction to
make cells resembling cartilage, bone, and muscle.
The finding potentially paves the way for scores of labs to generate new
stem cell lines without cloned embryos, which had long been considered the only realistic way of
making human stem cells in the short run.
Stem cells taken from
human embryos have been used to
make paralyzed rats walk again.
A new study, however, provides insights on the cellular mechanisms that might be targeted to help certain
stem cells - called
human mesenchymal
stem cells (hMSCs)- maintain properties needed to
make them clinically useful.
In 2004 Blackburn and ethicist William F. May
made headlines when the Bush administration ousted them from the President's Council on Bioethics for their strong public support of
human embryonic
stem cell research.
The method, which involves inserting genetic material that
makes the
cells» development run backwards, opens the door to
stem cells specific to patients, which could be used to repair damaged organs or fight diseases such as Parkinson's and diabetes — crucially, all without the need to destroy
human embryos.
«Cellular system
makes the battle against a rare disease personal: Scientists develop the first
human stem -
cell based system to find drugs to fight mitochondrial disease.»
The patch consists of eye
cells made from
human embryonic
stem cells.
Naïve
stem cells are blank slates that form the basis for not only all the
cells of the
human body, but
cells that
make up the placenta to support an embryo as well.
Humans can
make new neurons, but only from specialised
stem cells.
Another team, from Stanford University, converted
human skin
cells directly into neurons without first stopping at the
stem cell stage, potentially
making the process more efficient.
Thirteen European
stem cell scientists have issued a public appeal to the European Court of Justice (ECJ) not to prohibit patents on discoveries
made with
human embryonic
stem (hES)
cells.
Now a team has used
stem cells from
human cord blood to
make cells that produce EPO.
He used adult
cells — first in mice, although the technique is now feasible in
human cells — to
make stem cells that can form a wide range of other
cells, essentially turning their cellular clocks back to infancy so they could mature into different adults.
«This is essentially a recipe for how to
make human inner ears from
stem cells,» said Dr. Koehler, lead author of the study and whose research lab works on modeling
human development.
Intrigued, the team inserted a
human version of L1 into rat neural
stem cells, along with a marker that would
make the
cells glow green whenever L1
made a jump.
In mice and
humans alike, the cerebral cortex — the outermost layer of brain tissue associated with high - level functions such as memory and decision -
making — starts out as a spherical sheet of tissue
made up of only neural
stem cells.
But no one has yet succeeded in
making human embryonic
stem cells by cloning.
That still
makes them a potential source of ES
cells, and because
human parthenote embryos can't develop to term, some people have fewer qualms about using them to produce
stem cells.
That
made working with the mini-brains expensive, given the high cost of the nutrients needed to cultivate
human stem cells in the lab, he says, as well as the expense of chemical growth factors that guide the tissue to organize itself like a real brain.
However, those
stem cells, which were
made from
human embryos that had been donated for research after in vitro fertilization procedures, can be difficult to come by.
The germ
cells made from
stem cells stopped differentiating in the mice before they produced mature sperm (likely because of the significant differences between the reproductive processes of
humans and mice) regardless of the fertility status of the men from whom they were derived.
As
stem cells continue their gradual transition from the lab to the clinic, a research group at the University of Wisconsin — Madison has discovered a new way to
make large concentrations of skeletal muscle
cells and muscle progenitors from
human stem cells.
The Zeng lab is
making great progress on developing a
stem cell - derived treatment for Parkinson's disease for testing in
humans.
The group says that their recommendations are intended to «uphold overriding societal goals» by promoting global justice and
human dignity in seeking to ensure that the medical benefits of
stem cell research are
made widely accessible.