Sentences with phrase «human stem cells show»

Human stem cells show much promise for regenerative medicine because they can transform into various specialized cell types, including bone and cartilage cells.

Muscles from mice treated with modified human stem cells show human dystrophin - producing muscle fibers (yellow) integrated among mouse muscle fibers (red).

Laboratory tests, where the membrane was applied to human stem cells shows very encouraging results.

Not exact matches

«We've been hearing about their potential for more than a decade, but the results have always been in mice and rats, and no one has shown they're safe or effective in humans long term,» says Robert Lanza of Advanced Cell Technology in Marlborough, Massachusetts, the company that carried out the stem cell interventCell Technology in Marlborough, Massachusetts, the company that carried out the stem cell interventcell intervention.

In August 2006, Lanza and his co-authors published a paper in Nature showing that a single cell could be plucked from an 8 -10-cell human embryo and grown into stem cells.

Previous research shows human induced pluripotent stem cells (hiPSCs)-- generated directly from adult cells — can express markers for a wide variety of cells, including those that secrete NP.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

This image shows an implanted graft of cardiac cells derived from human stem cells (green) meshed and beat with primates» heart cells (red).

Varghese and her team showed that they could control the differentiation of human pluripotent stem cells into functional osteoblasts — bone - building cells — simply by adding the molecule adenosine to their growth medium.

Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.

The two reports also showed that Zika virus infected and damaged neuronal stem cells harvested from mice and humans.

The results obtained by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in Human and Molecular Biology show, for the first time, using mice, that pluripotent stem cells differentiated into cortical neurons make it possible to reestablish damaged adult cortical circuits, both neuroanatomically and functionally.

Clinical trials have shown that injection of human umbilical stem cells, or hUTC, into the retina helps preserve and restore vision in macular degeneration patients.

The results, which are published in the scientific journal Scientific Reports, show that human stem cells that are transplanted to the injured spinal cord contribute to restoration of some sensory functions.

The vlincRNAs were shown to be present in cancerous cells as well as stem cells and normal human tissues.

Ko first cloned the human GT198 gene while a postdoctoral fellow at Harvard Medical School, and subsequent studies by her and others have shown it has multiple roles that also include regulating stem cells, cell suicide and turning other genes off and on.

Investigators at the Cedars - Sinai Heart Institute — whose previous research showed that cardiac stem cell therapy reduces scarring and regenerates healthy tissue after a heart attack in humans — have identified components of those stem cells responsible for the beneficial effects.

In the new study, Lipton and his colleagues used human stem cell and mouse models to show exactly how SNO can trigger cell death in Parkinson's disease.

Prior research with cultured tissue had shown that a mix of chemicals could change bone marrow stem cells from mice to those resembling brain cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the same brew on human cells, the number altered was modest.

Most experiments with human stem cells have only shown that the cells can acquire the phenotype of various differentiated cell types, but have not shown that the cells are functional at the transplantation site.

Last month, Shinya Yamanaka at Kyoto University showed he could transform adult skin cells into cells akin to human embryonic stem cells.

In a statement put on the Web this morning, NIH reported that all 64 lines «show characteristics of stem cell morphology» and have undergone several population doublings, and most of them have demonstrated all the protein markers «known to be associated with human embryonic stem cells.»

The existence of cancer stem cells has already been reported in a number of human cancers, explains Professor Jacobsen, but previous findings have remained controversial since the lab tests used to establish the identity of cancer stem cells have been shown to be unreliable and, in any case, do not reflect the «real situation» in an intact tumour in a patient.

This image shows an expression of the stem cell gene Musashi in human pancreatic cancer.

Stem cells obtained in mice also show totipotent characteristics never generated in a laboratory, equivalent to those present in human embryos at the 72 - hour stage of development, when they are composed of just 16 cells.

Finally, the group examined human neural stem cells extracted from people with schizophrenia and found that these, too, showed higher levels of L1.

Recent research by neuroscientist Fred Gage and colleagues at the University of California (UC), San Diego, has shown that one of the most common types of jumping gene in people, called L1, is particularly abundant in human stem cells in the brain that ultimately differentiate into neurons and plays an important role in regulating neuronal development and proliferation.

Using stem cells harvested from human bone marrow, researchers transplanted cells into mice modeling ALS and already showing disease symptoms.

A study published today in Science shows that the Zika virus hijacks a human protein called Musashi - 1 (MSI1) to allow it to replicate in, and kill, neural stem cells.

Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.

The mice show many of the symptoms that human patients do, and so they were an especially good candidate to test iPS cells» abilities, says stem cell researcher Rudolf Jaenisch of the Whitehead Institute for Biomedical Research and the Massachusetts Institute of Technology, both in Cambridge, who collaborated with Townes on the project.

Skin cells reprogrammed to act like embryonic stem cells — a breakthrough first reported in human cells 2 weeks ago — are already showing promise as a therapeutic agent.

One team in Japan, and another in the US, have independently shown it is possible to produce embryonic - like stem cells directly from a patient's own skin cells without having to create and destroy a cloned human embryo first.

Human embryonic stem cell - derived neurons (green) showing nuclei in blue.

Experiments conducted by lead author Fatima Syed - Picard, Ph.D., also of Pitt's Department of Ophthalmology, and the team showed that stem cells of the dental pulp, obtained from routine human third molar, or wisdom tooth, extractions performed at Pitt's School of Dental Medicine, could be turned into corneal stromal cells called keratocytes, which have the same embryonic origin.

In 2009, Reijo Pera showed that it is possible to generate functional, sperm - producing germ cells from human embryonic stem cells grown under certain conditions in the laboratory.

Though Hwang Woo - suk, a South Korean scientist claimed to have created the first human embryonic clone and derived a stem - cell line from it in 2004 his work was later shown to be fraudulent.

In this image, a novel type of human stem cell is shown in green integrating and developing into the surrounding cells of a nonviable mouse embryo.

They have already shown that they can transform human fibroblast cells into pluripotent stem cells, and now plan to start working on delivering the proteins needed to differentiate stem cells into specialized tissues.

At present, there are no embryonic stem - cell treatments approved by the US Food and Drug Administration, and most human studies of such therapies have shown unremarkable results.

If we can show an improvement in those adult stem cells it may not be that big a jump to humans, where COPD increases with age.»

Here we show that it is feasible to differentiate and mature human embryonic stem cells (hESCs) into functional -LSB-...]

Scientists at the University of Cambridge have for the first time shown that it is possible to derive from a human embryo so - called «naïve» pluripotent stem cells — one of the most flexible types of stem cell, which can develop into all human tissue other than the placenta.

One caveat is that the authors also observed that one of the eight human embryonic stem cell lines established following spindle transfer showed a drift in mitochondrial heteroplasmy in a subset of stem cells, despite low levels of carryover detected in the embryo.

A recently published paper showed that mice with colon cancer can be «vaccinated» with human embryonic stem cells and have a significant immune response against the cancer (Li et al., 2009).

The work, as detailed in the journal Stem Cells, shows that only a bit of creative manipulation is needed to turn skin cells into human white blood cCells, shows that only a bit of creative manipulation is needed to turn skin cells into human white blood ccells into human white blood cellscells.

Here, we show that a non-adherent, stem - like, and metastatic CSC - enriched subpopulation could be isolated by exposing human metastatic breast cancer cell lines to cycles of chronic hypoxia followed by reoxygenation.

Human heart cells grown from stem cells show less - robust muscle fibers (green) in the presence of high levels of glucose (left) than when glucose levels were lower (right).

The group recently produced data showing that stem cells from human hair follicles also differentiate into contractile smooth muscle cells.

He and colleagues have also succeeded in differentiating human pluripotent stem cells into retinal (RPE) cells, and has shown that they provide long - term benefit in animal models of vision loss.