Lee SJ, Wang H - J, Kim T - H, et al., In Situ Tissue Regeneration of Renal Tissue Induced by Collagen
Hydrogel Injection.
Review of «In Situ Tissue Regeneration of Renal Tissue Induced by Collagen
Hydrogel Injection» from STEM CELLS Translational Medicine by Stuart P. Atkinson
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Not exact matches
The
injection is made up of a mixture of VentriGelTM, a
hydrogel derived from scaffolding protein that is extracted naturally from the heart.
(Right to Left) NTU Assoc Prof Andrew Tan, NTU Asst Prof Cleo Choong and their clinical partner Dr Marcus Wong, holding the various applications containing ANGPTL4, which included a sponge, filler, gel patch, paste,
hydrogel and
injection.
Compared to other types of
hydrogels being developed (left), a new
hydrogel (right) can form crosslinks after
injection into the heart, making the material stiffer and longer - lasting.
For instance, his group developed a
hydrogel that forms additional crosslinks between the polymer chains after
injection.
In pre-clinical studies conducted by the researchers, a one - time, local
injection of the
hydrogel - drug combo prevented graft rejection for more than 100 days compared to 35.5 days for recipients receiving only tacrolimus and 11 days for recipients without treatment or only receiving
hydrogel.
Two days after the nanosponge -
hydrogel was injected underneath the skin of a mouse, nearly 80 percent of the nanosponges were still found at the
injection site.