Sentences with phrase «hyperexcitability in»

Hyperexcitability in combined entorhinal / hippocampal slices of adult rat after exposure to brain - derived neurotrophic factor

Catego also contains Fipronil which we already know as effective in inducing death in fleas by creating hyperexcitability in their nervous system structures.

Working with motor neurons derived from ALS patients and healthy controls, Dr. Wainger performed fundamental electrophysiological characterization and identified motor neuron hyperexcitability in ALS patient - derived motor neurons (Wainger et al., 2014).

Using whole - cell path clamp, both dSPNs and iSPNs from Q175 6 - month old mice showed elevated membrane resistance and reduced rheobase current, consistent with previous reports of SPN hyperexcitability in mouse models of HD.

The team found the same hyperexcitability in the lymphocyte - derived neurons, validating their earlier results.

Not exact matches

However, detailed understanding of the molecular basis for the role of neuronal KV7 channels in hyperexcitability syndromes has been lacking.

The team found that maintaining some people's neurons in a lithium - infused medium calmed this hyperexcitability.

It fits with previous research that shows mGluR5 is important for hyperexcitability, but in a different way than we had thought.»

In the absence of vitamin D, dietary calcium is not properly absorbed, resulting in hypocalcemia, leading to skeletal and dental deformities and neuromuscular symptoms, e.g. hyperexcitabilitIn the absence of vitamin D, dietary calcium is not properly absorbed, resulting in hypocalcemia, leading to skeletal and dental deformities and neuromuscular symptoms, e.g. hyperexcitabilitin hypocalcemia, leading to skeletal and dental deformities and neuromuscular symptoms, e.g. hyperexcitability.

If a new drug, for instance, reverses the hyperexcitability at the cellular level, it would likely treat bipolar disorder in patients.

«If hyperexcitability is the brain network basis for these symptoms, then reducing neuronal excitability with certain drugs that modulate inhibition could be of therapeutic value in these devastating neurodevelopmental disorders.»

«Essentially, they cause acetylcholine to build up in the brain, causing hyperexcitability of neurons as well as the death of some neurons, which leads to inflammation in the brain,» said Ashok K. Shetty, PhD, a professor in the Department of Molecular and Cellular Medicine at the Texas A&M College of Medicine, associate director of the Institute for Regenerative Medicine, research career scientist at the Olin E. Teague Veterans Medical Center, Central Texas Veterans Health Care System and senior author of the paper.

In epilepsy, spermine levels decrease, causing hyperexcitability.

That, Goel said, mirrors the hyperexcitability seen in some individuals with the syndrome.

Hyperexcitability as a result of this imbalance has been hypothesized to contribute to poorly functionally differentiated and inherently unstable cortex in autism (Rubenstein and Merzenich, 2003).

66/4: 15 Hyperexcitability of neurons and cardiomyocytes in a mouse model of SCN8A epileptic encephalopathy.

We see clinical signs varying from vomiting, diarrhea (with secondary pancreatitis in severe causes), to neurologic signs which include stumbling gait, weakness or hyperexcitability, seizures to coma, and occasionally cardiac arrhythmias.

AMANTADINE This drug acts to modulate the pain response by antagonizing the N - methyl - d - aspartate (NMDA) receptor and the role they play in central neuronal hyperexcitability (wind up).

Other clinical signs may include fever, weakness or paralysis of hind limbs, impaired vision, ataxia, aimless wandering, walking in circles, hyperexcitability or coma.7 If horse owners notice signs or symptoms of WNV infection in their horses, they should contact a veterinarian immediately, especially if horses are exhibiting neurological signs.

According to ASPCA Poison Control, tobacco toxicity can result in hyperexcitability then depression, vomiting, incoordination, paralysis and possibly death.

Other clinical signs may include fever, weakness or paralysis of hind limbs, impaired vision, ataxia, aimless wandering, walking in circles, hyperexcitability or coma.6 If horse owners notice signs or symptoms of West Nile infection in their horses, they should contact a veterinarian immediately.

Other clinical signs may include fever, weakness or paralysis of hind limbs, impaired vision, ataxia, aimless wandering, walking in circles, hyperexcitability or coma.4 Horse owners should contact their veterinarian immediately if they notice any of these behaviors.

Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability