Sentences with phrase «ihc diagnostic assays»

Diagnostic assays for on - farm use have different constraints compared with those used in traditional laboratory environment

The scientists next plan to evaluate the precise roles of the five genes and to validate the accuracy of their diagnostic assay in a prospective clinical study.

The Institute hopes to eventually obtain viral isolates for medical countermeasure development and receive data on the performance of the diagnostic assays.

So we wanted to elucidate the molecular basis of that resistance in the population and design a field applicable diagnostic assay for its monitoring.»

NIAID's Bradley Groveman, foreground, and Christina Orru using the RT - QuIC diagnostic assay, which they helped adapt to detect Parkinson's disease and dementia with Lewy bodies.

It will be extremely important to identify and characterize those viruses as quickly as possible — to get a head start on the development of diagnostic assays for surveillance and drugs, or vaccines for treatment — before they have a chance to really spread.»

The need for diagnostic devices for biodefense is not going away, Singh said, since there are always new diseases springing up that lack good diagnostic assays.

Use of genomics to design a diagnostic assay to discriminate between Streptococcus pneumoniae and Streptococcus pseudopneumoniae — Matthew A. Croxen — Microbial Genomics

Within our lab we exploit the unique DNA methylation profiles of brain cells to create molecular diagnostic assays capable of detecting peripheral neurological cell free DNA.

The study compared four PD - L1 IHC diagnostic assays developed in conjunction with four PD - 1 / PD - L1 immune checkpoint inhibitors, which are used in NSCLC clinical trials.

«Eight men and women associated with the Biotech Center have discovered drugs and diagnostic assays that are in human use today — and more innovations lie ahead.»

Esko is collaborating with Zacharon Pharmaceuticals, a San Diego - based biotechnology company, to develop a commercial diagnostic assay for differentiating forms of MPS from urine and blood samples, a screening test for newborns and a tool for measuring the biochemical response of MPS patients to existing and novel therapies.

Currently research interests revolve around transfusion - transmitted viruses, blood screening and diagnostics assays, and transfusion efficacy.

SEngine Precision Medicine, instead, is pursuing an innovative approach for the development of novel targets and drugs for cancer therapy by using primary patient organoids initially derived for our diagnostic assay.

Dr. Manak has helped set up and direct various collaborative programs with developers of infectious disease tests including Hologic, Roche, Bio-Rad, SpotOn and SeraCare as well as partnerships with government agencies for evaluation of diagnostic assays and devices.

Prior to Joining MHRP, Dr. Manak was the Chief Scientist of SeraCare Life Sciences Inc., where he led the development of seroconversion and performance panels widely used by the in vitro diagnostics community for development, evaluation and validation of in vitro diagnostic assays used in screening and monitoring of infectious diseases.

All samples were from patients whose lesions had previously tested negative using the current CDC diagnostic assay in widespread use.

A potential problem is that vaccinated cats will also test positive on the routine tests used to detect FIV - infected cats, but newer diagnostic assays are becoming available that may overcome this problem.

Identification of Borrelia burgdorferi OspC genotypes in canine tissue following tick infestation: implications for Lyme disease vaccine and diagnostic assay design.

Represented Becton, Dickinson and Company in a patent infringement suit brought by Gen - Probe involving methods of automating nucleic acid diagnostic assays and related consumable products.

Executed and documented experimental test designs for donor screening and diagnostic assays, feasibility of a new donor screening system

Accomplished and highly motivated research professional with extensive experience in infectious disease (hepatitis C virus (HCV), Respiratory syncytial virus (RSV), dengue viruses, Herpes virus (HSV) and influenza viruses) in vaccine development, assay design, development and validation / verification molecular diagnostic assay (MGB - Pleiades chemistry).

Not exact matches

Headquartered in Raritan, New Jersey, Ortho - Clinical produces in - vitro diagnostics equipment and associated assays and reagents.

NEW YORK (360Dx)-- Biotech firm Berg continued its push into cancer diagnostics with the presentation of several posters earlier this month at the annual meeting of the American Association for Cancer Research and the preparation of a forthcoming publication detailing an assay for distinguishing between prostate cancer and benign prostate hyperplasia.

Notably, the Sierra Leonean genomes differ from PCR probes for four separate assays used for EBOV and pan-filovirus diagnostics (table S3).

Qiagen creates sample and assay technologies for use in research, applied testing, and molecular diagnostics and has about 2,600 employees worldwide.

Fully implemented targeted sequencing - based assays in routine diagnostic pathology laboratories are currently lacking in lymphoid cancer care,» explained Christian Steidl, MD, Senior Scientist at the BC Cancer and Associate Professor in the Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

Molecular logic Assays using molecular computers, however, could simplify biomedical diagnostics.

In 2011, she joined the institution's molecular diagnostics laboratory where she has been developing translational next generation sequencing assays and bioinformatics workflows for the Molecular Tumor Profiling Lab of the Yale Cancer Center.

The investigators believe the assay they developed to discover the mutation may hold promise as a diagnostic for predicting male progression to cirrhosis and liver cancer.

The prospective cohort study met both its primary endpoints: to determine the association between troponin T levels measured by a high - sensitivity troponin T assay and the risk of death within a month of non-cardiac surgery, and to identify diagnostic criteria for myocardial injury after non-cardiac surgery that defines whether or not serious injury to the heart has occurred.

The Showe Laboratory will be performing the optimization and validation of the prototype glioblastoma diagnostic test, transferring the assay to a more versatile technology platform that is better suited for clinical applications.

• Customized mutation screening assays Biotage, the manufacturing company of the genetic analyzer PyroMark ID, offers in its database more than 1,000 customized assays for routine clinical screening diagnostics.

This gene is identified by an investigational FLT3 Mutation Assay companion diagnostic a specific lab test of their blood or bone marrow, which is used to see if they have a mutation of the FLT3 gene.

Whole swathes of diagnostic tests may eventually be replaced with a single assay - sequencing - as we reach the «sequencing singularity».

Functional understanding of candidate proteins is vital to assay development, compound design, and diagnostic / prognostic utilizations.

SEATTLE, Feb. 05, 2018 (GLOBE NEWSWIRE)-- NanoString Technologies, Inc. (NASDAQ: NSTG), a provider of life science tools for translational research and molecular diagnostic products, today announced the publication of a landmark study in which Danish researchers used the Prosigna ® Breast Cancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and 2003.

DENVER — A pre-competitive consortia of pharmaceutical, diagnostic companies and academic associations, including the International Association for the Study of Lung Cancer (IASLC), announced phase I results of the «BLUEPRINT PD - L1 IHC ASSAY COMPARISON PROJECT» at the Annual Meeting of the American Association for Cancer Research (AACR) on April 19.

This effort, which will enhance deCODE's proprietary gene and drug target discovery work and may provide genetic markers for additional diagnostic development, will leverage Illumina's Sentrix ® HumanHap BeadChips; Infinium ™ assay and LIMS (laboratory information management system); as well as analysis and visualization tools from Illumina's BeadStudio software.

This assay will be a useful tool for differential Zika fever diagnostics in a situation where number of other disease like malaria, dengue, chikungunya co-circulate and are clinically indistinguishable.

Diagnostic Utility of a Clonality Test for Lymphoproliferative Diseases in Koreans Using the BIOMED - 2 PCR Assay.

Four of the mAbs, 2T5C9, 2G9C, T1F11, and TB2H7, demonstrated diagnostic potential in enzyme - linked immunosorbent assays (ELISA) by their low to sub-nanomolar cross-reactivity with recombinant wild - type (WT) and mutant TTR aggregates and lack of binding to native TTR or amyloid fibrils formed by other peptides or proteins.

We provide a full - range of standardized CE - marked in vitro diagnostic products for hematology - oncology, as well as RUO assays, analyte specific reagents (ASRs), and DNA & RNA controls.

As a reagent manufacturer, we offer a comprehensive selection of gel, capillary, and next - generation sequencing PCR assays for gene rearrangement, chromosome translocation, and gene mutation detection as analyte specific reagents (United States), research use only, or CE - marked in vitro diagnostics to laboratories (outside of North America).

The LymphoTrack ® Dx TRB Assay for the Illumina MiSeq ® is an in vitro diagnostic product intended for next - generation sequencing (NGS) based determination of the frequency distribution of TRB gene rearrangements in patients suspected with having lymphoproliferative disease.

Dr. Shendure's research group in Seattle pioneered exome sequencing and its earliest applications to gene discovery for Mendelian disorders (e.g. Miller and Kabuki syndrome) and autism; cell - free DNA diagnostics for cancer and reproductive medicine; massively parallel reporter assays and saturation genome editing; whole organism lineage tracing; and massively parallel molecular profiling of single cells.

Currently, Vaijayanti leads Strand's translational clinical research team that designs and validates next - generation sequencing and molecular assays for Strand's clinical diagnostics offering in personalized medicine.

Blood Systems Research Institute (BSRI) today announced a collaboration to more precisely and efficiently measure the human immunodeficiency virus (HIV) latent reservoir in clinical samples using the Panther system from Hologic, Inc. — a fully automated molecular diagnostics platform that provides test consolidation, random - access sample loading, and proven assay chemistry.

The SCIEX clinical diagnostic portfolio includes an FDA - cleared assay for in vitro diagnostic use, mass spectrometers and fully integrated LC - MS / MS systems with easy to learn, intuitive software.

CLINIQA, ISO 13485:2003 / 9001:2008 certified, is a clinical diagnostics manufacturer of diagnostic test kits / assays, quality controls, calibrators, linearity calibration verifiers, reagents, proficiency testing materials as well as biological raw materials used worldwide.