Identification of these genes provides support for previously hypothesized mechanisms of high - altitude adaptation and illuminates the complexity of hypoxia - response pathways in humans.
Not exact matches
«Now that we have narrowed down the hunting ground, these findings
provide us with a focused direction for
identification of the
gene itself.»
Identification of a
gene needed to expand light harvesting in photosynthesis into the far - red - light spectrum
provides clues to the development
of oxygen - producing photosynthesis, an evolutionary advance that changed the history
of life on Earth.
The
identification of genes that are synthetically lethal in β - catenin - activated cancer cells would
provide new targets for therapeutic drug design.
GOMiner — To
provide additional statistical stringency to the
identification of potential targets, we then analyzed the data sets generated by the SAM - RS analysis
of the microarray data for hypoxia - associated coregulation
of multiple, functionally related
genes.
«If we can establish a link between abnormal forms
of this
gene and ADHD, it could
provide us with a powerful new tool for precise diagnosis and early
identification of children at risk, and a signpost toward designing better drug treatment,» said Ed Cook, associate professor
of psychiatry and
of pediatrics at the University
of Chicago and lead author
of the report.
First,
identification of new Alzheimer's disease
genes will
provide major clues as to its underlying cause.
«
Identification of genes that contribute to Alzheimer's risk and that influence the progression
of disease will help lead us to the cause
of the disease, identify proteins and other new targets for drug development, and
provide genetic methods for determining which people are at greatest risk for Alzheimer's disease when preventative measures become available,» said Dr. Schellenberg.
Identification of genes that contribute to Alzheimer's disease risk and that influence other characteristics
of Alzheimer's disease will reveal basic pathogenic mechanisms, identify proteins and pathways for drug development, and
provide genetic methods for determining people at greatest risk for when preventative measures become available.
Careful manual annotation
of the human reference sequence
provides a solid basis for the
identification of disease - associated
genes.
DNA barcoding aims to
provide an efficient method for species - level
identifications using an array
of species specific molecular tags derived from the 5 ′ region
of the mitochondrial cytochrome c oxidase I (COI)
gene.
Collectively these tools
provided a robust means to interrogate tumor specimens for changes to the genome, which lead to
identification of genomic regions and
genes associated with cancer.
The increased power
provided by looking for specific
gene candidate variations rather than linked markers will aid the
identification of epilepsy risk factors, perhaps leading to development
of DNA tests to enable breeders to select against such risk factors.