Identifying gene expression patterns in relation to the compound could facilitate the selection of the most appropriate patient cohorts for clinical development.
Not exact matches
Once the
pattern of
expression of these
genes had been
identified, Prof. Khatri and his colleagues tested it out on the remaining 900 samples from patients with different tropical diseases and from healthy people.
To
identify genes involved in the
patterning of adult structures, Gal4 - UAS (upstream activating site) technology was used to visualize
patterns of
gene expression directly in living flies.
Research published this month in Nature Neuroscience
identified a surprisingly small set of molecular
patterns that dominate
gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.
By comparing
gene expression in the lungs of ducks infected with either highly or weakly pathogenic avian influenza H5N1 viruses, the team
identified genes whose
expression patterns were altered in response to avian influenza viruses.
We
identified species - specific
gene expression patterns indicating that changes in protein and
gene expression have been particularly pronounced in the human brain.
To
identify transcriptional
patterns that correlate with body mass, we used oligonucleotide microarrays to catalogue
gene expression levels in the parametrial or epididymal adipose tissue from two dozen mice whose body mass and adiposity varied due to diet, sex, and mutations in
genes affecting energy homeostasis.
Using genechip technology, a powerful tool for analyzing the
expression patterns of thousands of
genes at a time, researchers have
identified a number of
genes that are specifically regulated by the...
Analyzing
patterns of
gene expression in individual human immune system cells, the researchers refined the definitions of the types known as dendritic cells and monocytes and
identified a novel type that had been overlooked.
We
identify no overt
pattern in the
expression of either VR or OR
genes based on cluster or genomic location (Figure 4, 5).
Now researchers at the Salk Institute for Biological Studies have
identified an essential cellular pathway in zebrafish that paves the way for limb regeneration by unlocking
gene expression patterns last seen during embryonic development.
As an illustration, let us look at the
expression patterns of a number of
genes identified with different FSVs in the zebrafish embryo.
The authors
identify ten sub-regions based on differential
gene expression, combining the
expression patterns of GAL4 driver lines and RNA seq. of dissected segments of the gut.