Sentences with phrase «identifying mechanisms of»

Identifying mechanisms of associations between child adversity and future psychiatric illnesses could inform early interventions.

To achieve this goal, the center's clinical and basic investigators are engaging in four distinct yet synergistic projects: 1) identifying mechanisms of abnormal cell proliferation, 2) examining the role of thrombosis in the development of PAH, 3) studying the role of nitric oxide deficiency in PAH, and 4) testing two existing drugs to restore lost cellular function due to a genetic mutation related to PAH.

So detecting such chemicals and identifying their mechanisms of action is of great importance for developmental scientists.

Beyond this general problem, Bellah, Habermas, and Luhmann seldom identify the mechanisms of cultural change.

Researchers at Roswell Park Cancer Institute (RPCI) have identified a mechanism of breast cancer cells that leads to chemotherapy resistance in inflammatory breast cancer.

To support the rights of indigenous communities to assert more control over their environment and resources, SIPPI published a handbook in 2003 to help local peoples understand and identify mechanisms of the current intellectual property regime that might be advantageous or detrimental to the protection of their environments, biological resources, and traditional knowledge.

«We're trying to identify the mechanisms of evolution as it's occurring in the wild» and translate it into a strategy to save the devils, Jones says.

Researchers have now identified the mechanism of chemotherapy - induced infertility in females.

The lab of Elisa Oricchio at EPFL has now carried out a study to identify mechanisms of resistance to ibrutinib.

The researchers said the work demonstrates that, in fact, multi-tissue, multi-individual data can be used to identify the mechanisms of gene regulation and help to study the genetic basis of complex diseases.

Designed to block the newly identified mechanism of PARP1 activation, these new inhibitors will specifically target PARP1, in contrast to the PARP1 inhibitors currently being tested in clinical trials.

Identify the mechanisms of autoreactive T effector and T regulatory expansion in man that can be harnessed to maintain or re-instate self - immune tolerance.

She is also involved in identifying the mechanism of action of anti-tubercular compounds.

Using flies in high throughput screening methods, we hope to identify the mechanisms of degeneration and to find ways to prevent or ameliorate the processes.

The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.

It wasn't until the 1960s that Vine and Mathews identified the mechanism of convective cells within the mantle.

Without understanding and identifying the mechanism of the teleconnection, there is no way of knowing whether the statistical results are realistic and not yet one more case of spurious correlation.

While most people thought it was obvious from everyday observation that the climate was self - regulating, scientists had not identified the mechanisms of regulation.

The paper, Noble gases identify the mechanisms of fugitive gas contamination in drinking - water wells overlying the Marcellus and Barnett Shales, was published in the Proceedings of the National Academy of Sciences (PNAS)

From this conceptual and empirical review, it is concluded that an overemphasis on clinical outcomes carries unnecessary risks (e.g., weak causal reasoning and a failure to identify mechanisms of change), while underemphasizing the several benefits of a more inclusive approach (e.g., increasing outcome research and improving supervision).

Not exact matches

Indeed, Google has long employed neural networks at many levels, from algorithms that identify pictures in Google images, aided by millions of Google users, to the underlying mechanisms of Google's ad technology.

In addition to employee education and awareness about how phishing attacks work and how to identify a suspicious email, it is an imperative that IT put filtering mechanisms in place that use technology — not people — to sort, test and eliminate such malicious emails before they even have a chance to test the eyes of the employees.»

While writing broadly about economic issues, Rosalie's research interest focuses on the implications of technology and innovation with the goal of identifying policy gaps, misaligned incentive mechanisms, and assessing potential causes and solutions.

Identifying resistance mechanisms and creating non-invasive tests to aid in the selection and monitoring of patients during clinical trials.

«With the Immunoscape platform, we are seeking to develop a molecular map of inflammatory diseases that will help us identify and characterize disease mechanisms,» Jessica Mega, chief medical officer for Verily, said in Monday's announcement.

Identify areas to be addressed as priority in terms of adverse impact, with focus on forced and migrant labour (in close collaboration with the Consumer Goods Forum), ethical recruitment and grievance mechanisms

That change was based on an in - depth study of the tackle, done to identify the mechanisms for head injury.

She was the first person to identify the physiological mechanisms responsible for social monogamy, and her research interests focus on the neurobiological basis of behavior and the developmental and epigenetic effects of early experience.

One study identified more serious injuries occurring when the child fell with a caretaker, 6,9 highlighting this as an important mechanism of injury for prevention efforts.

While identifying a clear target within the military bureaucracy and demonstrating the value of moral theorizing will likely prove difficult for Dr Leverinhaus's programme, ELAC's clearly defined partnership with a dozen humanitarian agencies and the immediate relevance of ethical principles on decision - making provide a strong mechanism for application.

It also identified performance - based governance with the setting up of appropriate mechanisms and frameworks to track performance in Millennium Development Agencies and government policies as benefit of the new initiatives.

Measures include; specialist teams at ports of entry, the launched of a Child Trafficking Telephone Advice line and a national referral mechanism to identify and support victims.

He noted that two - thirds of people identified under the national referral mechanism, which records trafficking incidents, were victims of sexual exploitation.

«We also urge the government to appoint «integrity advisors» as «early warning mechanism» for the SIP to monitor the implementation of the scheme across the states of the federation, identify and alert on any risks of fraud and corruption, and engage in analysing such risks, as well as in corruption prevention and reporting activities in general.

When looking into mechanisms that might affect the levels of SMN protein in neurons, the researchers scanned a genomic database called the UCSC Genome Browser and identified two genetic sequences that matched the opposite DNA strand of the SMN gene.

«If we identify mechanisms, then we can do more detection of disease risk.

A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy.

In this study published in Cell Reports, Alexandra Van Keymeulen and colleagues generated a new transgenic line - allowing lineage tracing of ER + luminal cells to investigate luminal cell heterogeneity and identify the origin of ER + luminal cells and the mechanisms regulating their pubertal expansion and adult maintenance.

«Now, research is needed to identify the mechanism that has evolved in these wild birds to disrupt the perpetuation of highly pathogenic influenza.»

«Nodding syndrome caused by response to parasitic protein, international study suggests: Study also identifies potential new mechanism for some forms of epilepsy.»

A new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.

In the study, the research team identified three distinctive characteristic regimes with regard to the degree of slip at the interface and revealed the underlying molecular mechanisms for each regime: (i) the z - to - x chain rotation mechanism in the vorticity plane in the weak flow regime, which effectively diminishes the wall friction against chain movement along the flow direction, (ii) the repetitive chain detachment - attachment (out - of - plane wagging) and disentanglement mechanism in the intermediate regime, and (iii) irregular (chaotic) chain rotation and tumbling mechanisms in the strong flow regime.

Researchers at the University of Zurich have now identified a mechanism how cells pass on the regulation of genetic information through epigenetic modifications.

«Dr. Rassool and her colleagues have identified an exciting new mechanism for attacking cancer that may ultimately provide a new option for treating patients with leukemia and other cancers,» says E. Albert Reece, MD, PhD, MBA, vice president for medical affairs at the University of Maryland and the John Z. and Akiko K. Bowers Distinguished Professor and dean of UMSOM.

Several of the network genes Volkan and her team identified have counterparts in humans and other vertebrates, which suggests the same basic mechanism could be at work in building the nervous system in other animals too.

Such research may help scientists understand the mechanisms that underlie aging and identify promising drug candidates that mimic the health - promoting effects of caloric restriction, says NIA's Felipe Sierra.

A better understanding of the mechanism that accelerates or restricts the development of cancer may allow, for example, the discovery of new biomarkers to better identify the population at greatest risk of colon cancer and even the current degree of risk.

«Our computer aided drug screening process has now identified two new classes of anti-cancer agents, specifically targeting two distinct and novel mechanisms underpinning cancer,» said Dr Andrea Brancale from Cardiff University's School of Pharmacy, who led on the compound's design.

It is expected that the molecular mechanisms underlying the inhibition of interferon signal transduction by C proteins would then be fully identified.

«We have identified the molecular mechanisms by which the Tat protein made by HIV interacts with the host cell to activate or repress several hundred human genes,» said Dr. Iván D'Orso, Assistant Professor of Microbiology at UT Southwestern and senior author of the study.