Sentences with phrase «if telomeres»

If telomeres become excessively diminished, the cell will become inflamed and eventually die.

If the Telomeres get too short, the cell's health is severely compromised, thereby, increasing your symptoms of aging.

If telomeres get too short, the cell can no longer divide and becomes inactive or dies.

If telomeres are too eroded, particularly in stem cells that replenish tissues later in life, this contributes to age - related diseases; but in cells where telomerase prevails, cancer can result.

If the telomeres get shorter, cells get more and more friendly to telomerase.

If our telomeres have grown dangerously short, can we do anything to keep them from shortening further?

There also is evidence the offspring of older parents have shorter telomeres, but it is not clear whether this is due to the offspring inheriting shorter telomeres or if their telomere loss during pre - or post-natal growth is higher.

If telomere restoration is all over the whole body, we'd need to verify, this too could get rid of senescent cells.

Not exact matches

Because of a quirk in the way the DNA is replicated, the ends are not completely copied, and that information would gradually be lost if not for the telomeres.

And maybe people who use the test can help clarify the connection between telomeres and health: If Telome Health lets users contribute (or actively entices them to contribute) their results and detailed medical histories to science, we could all help bring the picture into better focus.

The most important question for people taking the telomere test, though — whether you can do anything about your shrinking telomeres, if indeed they cause disease — is the one that still needs the most research.

How much a certain change — say, running or cutting back on fat — is going to affect your telomeres, if at all, is a level of specificity that the research can't yet provide.

Every time linear chromosomes are replicated during late S phase, the DNA polymerase complex is incapable of replicating all the way to the end of the chromosome; if it were not for telomeres, this would quickly result in the loss of vital genetic information, which is needed to sustain a cell's activities.

It is unclear whether shrinking telomeres will be problematic in culturing human tissue transplants, but if it turns out they are, Geron has an answer for that too.

The reason, he said, is that if a TERT promoter mutation arises to push a precancerous lesion — the mole or nevus — toward a melanoma, the chances are greater in someone with short telomeres that the cell will die before it up - regulates telomerase and immortalizes the cells.

So if growing up in an urban setting shortens birds» telomeres, it could lead to a host of other problems down the line, the team argues.

If cells fail to turn up telomerase, they also fail to immortalize, and eventually die from short telomeres because chromosomes stick together and then shatter when the cell divides.

If we introduced stem cells with nice, long telomeres in the first place, we could let them wind down and eventually be lost to apoptosis, senescence, or other sources of damage — and just top our tissues up with more stem cells before enough of those cells were lost to begin to impair tissue function.

So we might just be able to deal with cell loss if we had a sufficiently sophisticated program of stem cell replenishment — using cells engineered to lack the one linchpin function for cancer, namely telomere elongation.

If it weren't for telomerase, this gradual shortening would eventually lead to the complete loss of the telomeres in cells that replicate frequently during a life span, and thus the gradual erosion of the genes themselves.

They might do just fine, but if there's something else going on combined with the shorter telomeres, that might be enough to kill them.

If you're in the bottom third of telomere length, your cardiovascular disease risk goes up 40 percent, which is not a trivial number.

Dr. Anna Z. Pollack, lead author of the study, pointed out, «with cross-sectional data, we can't tell if having children is related to shortening of telomeres or merely whether women who have children start out with shorter telomeres.»

People carrying the variant might further accelerate the biological aging process if they smoke, are obese or don't exercise — all of which are bad news for telomeres.

If further studies confirm the role of the mutation, Rodriguez says, researchers might be able to develop anticancer agents to target cells with ATRX mutations or ALT to limit telomere length.

Parrish and researchers at her company decided it was time to see if stretching telomeres in people could also lengthen life.

Christopher Friesen, an author of the study from the University of Sydney, said: «We really don't know if shortened telomeres cause disease states or if they are a by - product of disease and ageing.

If this precious enzyme can stave off telomere shortening, then can't it also allow us to prevent death — or even reverse the effects of ageing?

If a nascent cancer can't find a way to seize hold of the telomerase - lengthening machinery, their telomeres will run down, their chromosomes will fray, and the cell will be destroyed before it can kill us.

The isoforms of this histone play complex regulatory roles in several cellular processes — epigenetic regulation of gene expression, selective regulation of developmental genes, and telomere maintenance — that could contributed to tumor growth and progression if dysregulated.

«In fact, if sheep like Dolly and other mammals made by this [cloning] technique are continually shown to be perfectly healthy and not age prematurely, that would just prove that the whole link between the telomeres and ageing is an unreliable one and not worth worrying about.»

Here are some of the compelling findings on cognitive ability, gut health and immunity, telomere lengthening, cellular homeostasis and longevity — all processes that, if optimized, can result in graceful aging.

But if you do a meditative yoga practice for 12 minutes every day, you make the telomeres longer again.

So, if looking youthful and full of energy is your main priority and you want to prevent the telomeres of shortening too fast and too soon, you know what to do.

If that's not enough to get your attention, another silent and insidious problem is that you may lose bone strength and bone density when cortisol is high, [i] although this is not conclusively proven in women of all ages, [ii] nor is it absolutely clear that run - of - the - mill chronic stress is causal when it comes to bone loss (though it certainly shortens telomeres).

I also was wondering if plant - based saturated fats such as those in peanut butter or perhaps palm oil shorten telomere length?

The strongest idea thT D. Oz cited on the human growth hormone debate was that it promotes telomere damage and that it will cause you to age quicker if you take HGH injections.

If we were to look at their DNA methylation age and the health of their telomeres, their biological age would be closer to 50.

And what would happen to telomere length if you combined sport with a diet containing a high level of protective substances?

If you listened to the podcast episode «Telomere Testing: Everything You Need To Know About A Cutting - Edge New Longevity Test That Tells You Your Cellular Age.

If you heat fish it will form oxidized cholesterol and this will shorten telomeres: Front Biosci (Elite Ed).

According to this article http://www.ncbi.nlm.nih.gov/pubmed/18996878 telomerase activity increases in the presence of cancer cells... if Dr Ornish's research was done on subjects with cancer... might not the increase in telomerase activity indicate that the cancer was progressing and not an indication that the telomere's were lengthening?

The new study was designed to determine if the lifestyle changes would affect telomere length and telomerase activity in these men over a longer time period.

«We found that women who sat longer did not have shorter telomere length if they exercised for at least 30 minutes a day, the national recommended guideline,» says Shadyab.