Sentences with phrase «immunoglobulin gene rearrangement»

Not exact matches

Two types of immature B cells, namely fetal liver hybridomas and the leukemic cell line 70Z / 3, both of which have cytoplasmic mu chains but no light chains, were examined for DNA rearrangements of their light chain and heavy chain immunoglobulin genes.

The results suggest that, although the lack of light chain synthesis can be due to a lack of gene rearrangement, there may also be transcriptional regulation, which may also be important for the expression of light chain immunoglobulins in immature B cells.

Detection of immunoglobulin heavy chain gene rearrangements in classic hodgkin lymphoma using commercially available BIOMED - 2 primers.

The antigen receptor genes that undergo rearrangements are the immunoglobulin heavy chain (IGH) and light chain loci (IGK and IGL) in B cells, and the T cell receptor gene loci (TRA, TRB, TRG and TRD) in T cells.

The laboratories also offer highly sensitive NGS - based MRD assays to track FLT3 mutations and patient - specific immunoglobulin and T - cell receptor gene rearrangements.

Invivoscribe products identify clonal rearrangements within the immunoglobulin and T - cell receptor genes, which helps identify clonal B - and T - cell populations.