Sentences with phrase «important gene interaction»

«Important gene interaction defined that drives aggressive brain cancer.»

Not exact matches

The issue should be understood as «which is more important, the individual replicator (the gene), or the patterns generated by interactions of a myriad of replicators with a complex environment?»

These drug - bug interactions could make microbial genes just as important as a person's genes for predicting how a drug will affect someone, says Matthew Redinbo of the University of North Carolina at Chapel Hill.

This finding, reported in today's Proceedings of the National Academy of Sciences, is an important example of a disease caused by the interaction of two genes.

Generally speaking, the genes humans got from Neanderthals or Denisovans are important for our interactions with the environment.

«This is a very important discovery that will guide future research efforts to explore the interactions of these pigmentary genes with other genetic and environmental risk factors in cancers not linked to sun exposure, such as eye melanoma.

This information is not only important because it can now help scientists try to understand how the differences between queen and worker may arise through interactions among genes, but also for the evolution of ants, and in the evolution of gene expression more generally.

Since proper functioning of the fat body is essential for the development of the female reproductive system after a blood meal, identifying which miRNAs are important to fat body functions, and what specific genes they target, can help design ways to manipulate the levels of microRNA or their targets, affect their interactions, disrupt mosquito reproduction, and thus prevent the spread of diseases the mosquitoes transmit.

Thus, interactome hubs such as NR1 may exhibit low levels of change in individual gene expression following hypoxia, but, based on analysis of interaction networks, are likely to play an important role in regulating the biologic response.

These genes have been shown to increase the risk of Crohn's disease, and are likely to play an important role in gut - bacteria interactions.

«Not only are these transcription factors vital for turning on certain genes, but their interaction is important to keep each other from going to the wrong place and turning on a set of genes that doesn't belong in a heart cell.»

This interaction is thought to be important in regulation of gene expression.

Second, we discovered that certain genes, namely Ncad expressed in the astrocytes, are important for optic nerve interaction with astrocytes, and for optic nerve regeneration.

Specifically, we have shown that the condensin subunit Cnd2 binds directly to the most important general transcription factor, the TATA box - binding protein TBP, and that TBP recruits condensin molecules onto RNA polymerase III - transcribed genes and highly active Pol II - transcribed genes (many ribosomal protein genes) through the Cnd2 - TBP interaction (Figure A).

Another important factor in reading and writing disabilities, READ1, a polymorphic compound with a short tandem repeat within intron 2 of risk gene DCDC2 may have a non-additive genetic interaction with KIAHap, a risk haplotype in risk gene KIAA0319 may be a transcriptional regulator of ETV and so also a transcriptional regulator of KIAA0319.

Boyce et al have looked at stress reactivity in children and have shown that a high degree of variability exists.21 Traditionally, genetic predispositions were thought to play a major role in determining stress reactivity, but more recent data suggest that previous experiences also play an important role.22 Stress reactivity, much like brain development itself, results from a complex, dynamic interaction between genes (nature) and the environment (nurture) over time.

Outline available evidence for why divorce may be an important environmental variable to examine in gene - environment interaction research.