Sentences with phrase «in proteomic analyses»

In proteomic analyses proteins are fragmented and identified by their mass and charge.

«By selecting only the very best preserved bone specimens and with various improvements in proteomic analysis, we were able to obtain roughly 90 per cent of the collagen sequence for both species,» said lead author Frido Welker, a PhD student at the Max Planck Institute for Evolutionary Anthropology and the University of York.

Not exact matches

The researchers employed an integrative approach that combined in vitro drug testing with proteomic and bioinformatic analysis.

The scientists hope to gain further insights from the proteomic analysis, in particular, because the DNA of syphilis decays very rapidly.

Branscomb also sees lots of opportunities in «techniques that are transforming scientific methodology, such as array technology, comparative genomic approaches, proteomics, sequence analysis.»

In contrast to the conventional approach of quantifying a few selected proteins, proteomic analysis allows the simultaneous quantification of thousands of proteins from a biological sample.

The researchers used a multitude of screening tools in this study to analyze the molecular components in the blood, including mass spectrometry - based quantitative proteomic, metabolomic and hematological analyses of blood cells.

«With advances in cancer proteomics that increase the speed of measurement, we are moving toward a future that includes genomic and proteomic analyses of patient tumors.»

Using mass spectrometry and bioinformatic analysis in close cooperation with the Core Facility Proteomics of the Helmholtz Zentrum München and the Bioinformatics and Computational Biology Department of the Technische Universität München, the researchers succeeded in precisely identifying a multitude of surface proteins.

When the researchers did a proteomic analysis of extracted fang blenny venom, they found three venom components — a neuropeptide that occurs in cone snail venom, a lipase similar to one from scorpions, and an opioid peptide.

Proteomic analysis of arginine methylation sites in human cells reveals dynamic regulation during transcriptional arrest.

Dr. Thrall also holds adjunct positions in the Graduate Research Program at Washington State University and regularly serves as a reviewer for panels for the National Institutes of Health in the area of proteomic and genomic analysis of the health effects of enviromental agents.

Two - Dimensional Gel Electrophoresis - Based Proteomic Analysis Reveals N - terminal Truncation of the Hsc70 Protein in Cotton Fibers In Vivin Cotton Fibers In VivIn Vivo.

Proteomics (Fagerberg et al, «Analysis of the human tissue - specific expression by genome - wide integration of transcriptomics and antibody - based proteomics») with a focus in the article on the tissue - specific pattern in the hProteomics (Fagerberg et al, «Analysis of the human tissue - specific expression by genome - wide integration of transcriptomics and antibody - based proteomics») with a focus in the article on the tissue - specific pattern in the hproteomics») with a focus in the article on the tissue - specific pattern in the human body.

Our technological expertise ranges from the most fundamental approaches to study membrane transport in lymphocytes and dendritic cells (subcellular compartmentalization, intravital microscopy, phagosomal functions), the systematic analysis of gene expression and it regulation (RNAseq, Chip Seq, proteomics) and physiological and pathological immune responses (mouse models for cancer immunity, immunomodulation / vaccination, human clinical studies in cancer).

We have identified another family required for RNA editing by immunoprecipitating ORRM1 and performing proteomic analysis in collaboration with the Van Wijk lab.

PathProt is the international forum for Pathway Analysis in Proteomics.

Proteomic analysis of gene expression in Golga3repro27 male infertility mice.

Proteomics analysis of other samples of bees from CCD colonies, conducted by the U.S. Army, yielded one of the earliest reports of Nosema ceranae and of Varroa destructor virus - 1 (VDV - 1)[6], as well as an RNA virus that was later identified as IAPV [7], in North American bees.

At the time that our proteomics analyses were conducted, the N. ceranae genome sequence was not available and only one N. ceranae sequence was available in the database.

BDNF induces widespread changes in synaptic protein content and up - regulates components of the translation machinery: an analysis using high - throughput proteomics.

Scientists at PNNL and the CDC previously conducted a global proteomics analysis of plasma and serum samples from the DASP and identified five candidates in a sample subset (Metz et al. 2008).

Identification of genes involved in gliding motility and proteomic analysis of spore inner membrane proteins in Clostridium perfringens.

Thorsten Baust (Hoflack, TUD)-- «Proteomic analysis of the sorting machineries involved in vesicular traffic between the biosynthetic» (2006)

Proteomics and phosphoproteomics analyses in melanoma cells identified CDK2 as a driver of resistance to both BRAF and Hsp90 inhibitors.

A systems level analysis reveals transcriptomic and proteomic complexity in Ixodes ricinus midgut and salivary glands during early attachment and feeding.

A proteomic analysis by mass spectrometry will be performed in serum.

Title: Proteomic analysis of the maternal protein restriction rat model for schizophrenia: Identification of translational changes in hormonal signaling pathways and glutamate neurotransmission Author: P. C. Guest et al..

Proteomic analysis to profile protein abundance resulted in the identification and relative quantification for 912 proteins with two or more unique peptides and 86 proteins with significant abundance changes after treatment with the neurotoxins, while microarray analyses to profile gene expression revealed 181 genes with significant changes in mRNA after treatment.

«Mitochondrial dysfunction, oxidative stress and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease.

According to a release from Dr. Hassan Dihazi, editor in chief, the journal covers all areas of proteomics including basic proteomic research; structural, functional, property, and interaction analysis of cellular systems, organelles, and protein complexes; and protein expression profiling for the discovery and validation of diagnostic and prognostic disease biomarkers.

He is currently collaborating with researchers in the lab on various projects related to HIV and ZIKA, including analyses regarding genomics, transcriptomics, and proteomics.

In this way, in - depth immunological monitoring, genetic and proteomic analyses, and biomarker discovery from patient samples guides further laboratory investigation, where mechanistic studies can be designed and animal modeling performeIn this way, in - depth immunological monitoring, genetic and proteomic analyses, and biomarker discovery from patient samples guides further laboratory investigation, where mechanistic studies can be designed and animal modeling performein - depth immunological monitoring, genetic and proteomic analyses, and biomarker discovery from patient samples guides further laboratory investigation, where mechanistic studies can be designed and animal modeling performed.

«The proteomics field is now entering a third generation phase where large - scale protein analysis will provide unique quantifiable data on a subcellular level «says one of the participants in the EU funded PROSPECTS project Dr. Emma Lundberg from the Science for Life Laboratory Stockholm.

His recent research has focused on the design and implementation of innovative algorithms to enable proteogenomic data analysis, pattern - based discovery of proteomic biomarker candidates, evaluation of data quality, assessment of variability and reproducibility in mass spectrometry based assays, and data visualization.

A proteomics analysis of cells that are prone to becoming cancer cells, described in Molecular & Cellular Proteomics, reveals clear signatures of mitochondrial and metabolproteomics analysis of cells that are prone to becoming cancer cells, described in Molecular & Cellular Proteomics, reveals clear signatures of mitochondrial and metabolProteomics, reveals clear signatures of mitochondrial and metabolic stress.

A combination of genomic (available here, here, here and here) and proteomic analyses indicated a glycoside hydrolase family 12 protein was critical in the high activity of one consortium.

Further study applying proteomic analysis confirmed that CAFs secrete more proteases, extracellular matrix proteins, and proteins that modify the basement membrane compared with NAFs, pointing to a remodeling role for CAFs in invasion.

Pooling samples provided sufficient protein mass for effective downstream proteomics analysis following immunoaffinity depletion of the 14 most abundant proteins present (representing approximately 95 % of the total protein mass in CSF), reducing the dynamic range of protein concentrations present in CSF, where proteins with highest concentrations mask proteins at lower concentrations from detection.

Finally, the genomic and proteomic analysis conducted from the blood samples collected within WP4 will be matched with the corresponding well - defined phenotypic data integrated in NeuroQUAST.

In this study, a shotgun proteomics analysis was conducted to profile the proteomic signature of the brain tissue of mice with experimental cerebral malaria (ECM) in order to further understand the underlying pathologIn this study, a shotgun proteomics analysis was conducted to profile the proteomic signature of the brain tissue of mice with experimental cerebral malaria (ECM) in order to further understand the underlying pathologin order to further understand the underlying pathology.

However, although many thousands of alternatively spliced transcripts are routinely detected in RNA - seq studies, reliable large - scale mass spectrometry - based proteomics analyses identify only a small fraction of annotated alternative isoforms.

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